Conservation of cis-Regulatory Syntax Underlying Deuterostome Gastrulation
CellsThroughout embryonic development, the shaping of the functional and morphological characteristics of embryos is orchestrated by an intricate interaction between transcription factors and cis-regulatory elements.
Lorena Buono +8 more
doaj +1 more source
Fog signaling has diverse roles in epithelial morphogenesis in insects
eLife, 2019 The Drosophila Fog pathway represents one of the best-understood signaling cascades controlling epithelial morphogenesis. During gastrulation, Fog induces apical cell constrictions that drive the invagination of mesoderm and posterior gut primordia.
Matthew Alan Benton +10 more
doaj +1 more source
Characterizing the zebrafish organizer: microsurgical analysis at the early-shield stage [PDF]
, 1996 The appearance of the embryonic shield, a slight thickening at the leading edge of the blastoderm during the formation of the germ ring, is one of the first signs of dorsoventral polarity in the zebrafish embryo.
Fraser, Scott E., Shih, John
core
The Histone‐Lysine N‐Methyltransferase (KMT2) Family in Health and Disease
MedComm, Volume 7, Issue 4, April 2026.This graphical abstract clarifies KMT2 family dysregulation and disease associations: its member mutations cause epigenetic imbalance and abnormal cell development; Menin/WDR5 inhibitors and other targeted therapies block aberrant epigenetic transcriptional programs, and combined synergistic therapies boost therapeutic efficacy.
Qiu Wang +8 more
wiley +1 more source
The FEBS Journal, Volume 293, Issue 8, Page 2248-2269, April 2026.Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola +11 more
wiley +1 more source
Identification of Binding Proteins in Xenopus laevis by MALDI-TOF/TOF Mass Spectrometry
Journal of Analytical Science and Technology, 2010 MALDI-TOF/TOF MS has been widely used for the identification of proteins in the proteomics field. Here we tried to identify novel proteins during vertebrate development by this MS and targeted the protein binding to Xenopus β-arrestin 2 (xβarr2).
Edmond Changkyun Park +5 more
doaj
Nuclear encoded mitochondrial ribosomal proteins are required to initiate gastrulation
, 2020 Agnes Cheong +5 more
openalex +2 more sources
Cell Division Drives Epithelial Cell Rearrangements during Gastrulation in Chick [PDF]
, 2016 João Firmino +4 more
openalex +1 more source
Mechanical bistability of the mesoderm epithelium facilitates mesoderm invagination during Drosophila gastrulation [PDF]
, 2021 Hanqing Guo, Michael Swan, Bing He
openalex +1 more source
A single-cell atlas of pig gastrulation as a resource for comparative embryology
Nature CommunicationsCell-fate decisions during mammalian gastrulation are poorly understood outside of rodent embryos. The embryonic disc of pig embryos mirrors humans, making them a useful proxy for studying gastrulation.
Luke Simpson +13 more
doaj +1 more source