Results 111 to 120 of about 69,462 (264)

Non-redundant roles for Profilin2 and Profilin1 during vertebrate gastrulation [PDF]

open access: yes, 2009
Gastrulation is a critical morphogenetic event during vertebrate embryogenesis, and it is comprised of directional cell movement resulting from the polarization and reorganization of the actin cytoskeleton.
Habas, Raymond   +2 more
core   +1 more source

High-throughput micropatterning platform reveals Nodal-dependent bisection of peri-gastrulation–associated versus preneurulation-associated fate patterning

open access: yesPLoS Biology, 2019
In vitro models of postimplantation human development are valuable to the fields of regenerative medicine and developmental biology. Here, we report characterization of a robust in vitro platform that enabled high-content screening of multiple human ...
Mukul Tewary   +16 more
semanticscholar   +1 more source

Establishment of Human Formative Pluripotent Stem Cell‐Like Cells Exhibiting Amniotic Differentiation Potentials

open access: yesCell Proliferation, EarlyView.
The hfPSC‐LCs could be established from naïve hESCs, conventional hESCs, hiPSCs, and human blastocysts. The hfPSC‐LCs hold robust capacity for three germ layers, hPGCLCs, and hALPCs. ABSTRACT Human embryos undergo pivotal morphogenetic remodelling shortly after implantation. The understanding of this crucial stage is severely impeded by the scarcity of
Xiaoxiao Wang   +11 more
wiley   +1 more source

Motor neuron development in zebrafish is altered by brief (5-hr) exposures to THC (∆9-tetrahydrocannabinol) or CBD (cannabidiol) during gastrulation

open access: yesScientific Reports, 2018
Marijuana is one of the most commonly used illicit recreational drugs and is widely used for medicinal purposes. The psychoactive ingredient in marijuana is ∆9-tetrahydrocannabinol (∆9-THC), whereas the major non-psychoactive ingredient is cannabidiol ...
K. T. Ahmed   +3 more
semanticscholar   +1 more source

Impacts of Ocean Acidification on Reproduction and Early Life Development in Marine Teleost Fish—A Synthesis

open access: yesFish and Fisheries, EarlyView.
ABSTRACT Ocean acidification (OA) remains a major and underexplored threat to marine fishes, particularly regarding reproductive physiology and early life stages (ELS). Although research over the past 15 years has documented diverse OA effects, substantial knowledge gaps persist.
Rebecca J. Bridge   +3 more
wiley   +1 more source

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

open access: yesExperimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

CTCF looping is established during gastrulation in medaka embryos

open access: yesbioRxiv, 2018
Genome architecture plays a critical role in gene regulation, but how the structures seen in mature cells emerge during embryonic development remains poorly understood.
Ryohei Nakamura   +14 more
semanticscholar   +1 more source

Essential embryology for the Canadian pathologists’ assistant

open access: yesAnatomical Sciences Education, Volume 19, Issue 7, Page 1134-1156, July 2026.
Abstract Pathologists' assistants (PAs) are pivotal in healthcare, conducting autopsies and examining tissues under a pathologist's guidance. Embryology knowledge is crucial for PAs to accurately assess anomalies and identify pathologies. Yet, it is often overlooked in academic PA training programs.
Samantha H. Nacci   +4 more
wiley   +1 more source

Zebrafish embryonic explants undergo genetically encoded self-assembly

open access: yeseLife, 2020
Embryonic stem cell cultures are thought to self-organize into embryoid bodies, able to undergo symmetry-breaking, germ layer specification and even morphogenesis.
Alexandra Schauer   +3 more
doaj   +1 more source

Cell Division Drives Epithelial Cell Rearrangements during Gastrulation in Chick

open access: yesDevelopmental Cell, 2016
Summary During early embryonic development, cells are organized as cohesive epithelial sheets that are continuously growing and remodeled without losing their integrity, giving rise to a wide array of tissue shapes.
João Firmino   +4 more
semanticscholar   +1 more source

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