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Human gastrulation: The embryo and its models.

Developmental Biology, 2021
Technical and ethical limitations create a challenge to study early human development, especially following the first 3 weeks of development after fertilization, when the fundamental aspects of the body plan are established through the process called ...
S. Ghimire   +3 more
semanticscholar   +1 more source

The primitive streak and cellular principles of building an amniote body through gastrulation

Science, 2021
Description The nonconserved primitive streak In human development, a linear structure called the primitive streak appears 14 days after fertilization. This structure marks the transition of the embryo from having radial to bilateral symmetry.
Guojun Sheng   +2 more
semanticscholar   +1 more source

Gastrulation

Current Opinion in Genetics & Development, 1991
At gastrulation, a single layer of cells is converted into an outer ectodermal covering, an inner ectodermal tube, and in triploblastic phyla, a middle mesodermal layer. This morphogenesis is driven by motility and directed by cell interactions, some of which involve adhesion and others that involve information transfer.
openaire   +3 more sources

Comparative analysis of human and mouse development: From zygote to pre-gastrulation.

Current Topics in Developmental Biology, 2020
Development of the mammalian embryo begins with formation of the totipotent zygote during fertilization. This initial cell is able to give rise to every embryonic tissue of the developing organism as well as all extra-embryonic lineages, such as the ...
Matteo A. Molè   +2 more
semanticscholar   +1 more source

Signaling regulation during gastrulation: Insights from mouse embryos and in vitro systems.

Current Topics in Developmental Biology, 2020
Gastrulation is the process whereby cells exit pluripotency and concomitantly acquire and pattern distinct cell fates. This is driven by the convergence of WNT, BMP, Nodal and FGF signals, which are tightly spatially and temporally controlled, resulting ...
Sophie M. Morgani, A. Hadjantonakis
semanticscholar   +1 more source

Vertebrate gastrulation

Current Opinion in Genetics & Development, 1992
Our understanding of the mechanisms that control gastrulation is still in its infancy. One problem is that gastrulation is a complex set of coordinated behaviours involving directional cell movements, several types of cell interactions, changes in cell fate and gene expression.
openaire   +2 more sources

Zebrafish gastrulation: Putting fate in motion.

Current Topics in Developmental Biology, 2020
Gastrulation entails specification and formation of three embryonic germ layers-ectoderm, mesoderm and endoderm-thereby establishing the basis for the future body plan.
D. Pinheiro, C. Heisenberg
semanticscholar   +1 more source

The evolution of vertebrate gastrulation

Development, 1994
ABSTRACT The availability of molecular markers now permits the analysis of the common elements of vertebrate gastrulation. While gastrulation appears to be very diverse in the verte brates, by analyzing a head-organizer marker, goosecoid, and a marker common to all forming mesoderm, Brachyury, we attempt to identify homologous structures
E M, De Robertis   +3 more
openaire   +2 more sources

Gastrulation and the Evolution of Development

Development, 1992
ABSTRACT The original eukaryotic cell may have possessed the key processes necessary for metazoan development -cell differentiation, patterning and motility - and these are present in the cell cycle. Protozoa also possess key patterning processes.
openaire   +2 more sources

Gastrulation in Drosophila

Seminars in Developmental Biology, 1994
Abstract The three germ layers in Drosophila are established by both the invagination of the ventral furrow, which internalizes the anterior midgut and mesoderm primordia, and the invagination of the posterior midgut primordium. The invaginations of these primordia occur by similar cell shape changes.
Rolf Reuter, José Casal
openaire   +3 more sources

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