Results 1 to 10 of about 46,994 (248)
Divergent lncRNA GATA3-AS1 Regulates GATA3 Transcription in T-Helper 2 Cells [PDF]
Frontiers in Immunology, 2018 Long non-coding RNAs (lncRNAs) possess a diverse array of regulatory functions including activation and silencing of gene transcription, regulation of splicing, and coordinating epigenetic modifications.
Hunter R. Gibbons +6 more
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Frontiers in Immunology, 2022 T helper-2 (Th2) cells and type 2 innate lymphoid cells (ILC2s) play crucial roles during type 2 immune responses; the transcription factor GATA3 is essential for the differentiation and functions of these cell types.
Rama K. Gurram +11 more
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The multi-faceted role of Gata3 in developmental haematopoiesis [PDF]
Open Biology, 2018 The transcription factor Gata3 is crucial for the development of several tissues and cell lineages both during development as well as postnatally. This importance is apparent from the early embryonic lethality following germline Gata3 deletion, with ...
Nada Zaidan, Katrin Ottersbach
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Endosalpingiosis Is Negative for GATA3 [PDF]
Archives of Pathology & Laboratory Medicine, 2021 Context.— Endosalpingiosis is a benign Müllerian inclusion that can mimic metastatic low-grade mammary carcinoma, particularly when encountered in axillary lymph nodes excised for breast cancer staging. Immunohistochemistry can be useful in histologically ambiguous cases, and a targeted immunopanel should include a ...
Marissa J, White +3 more
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Predictive value of GATA3 and Ki-67 expression in biopsy and transurethral resection specimens in patients with urothelial carcinoma of the urinary bladder [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2022 Introduction/Objective. Urothelial carcinoma is the most commonly diagnosed malignancy of urinary bladder in clinical and pathohistological practice where various prognostic factors play a significant role.
Šunjević Milena +2 more
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Whole-Exome Sequencing Reveals Pediatric Rare Syndromic Hearing Loss
罕见病研究, 2022 Objective To discuss the significance of genetic diagnosis of children with syndromic hearing loss by using whole-exome sequencing. Methods The clinical data of 34 children with sensorineural hearing loss were collected and the whole exons of genome of ...
QU Chunyan +5 more
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International Journal of Health Services Research and Policy, 2021 The purpose of our study is to examine immunohistochemically the correlation of GATA binding protein 3 (GATA3), E-cadherin, p53 and Ki-67 expression with histological type/molecular subtype and clinicopathological parameters in breast cancer. Methods and
Yeliz ARMAN KARAKAYA
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Journal of Clinical Pathology, 2023 GATA binding protein 3 (GATA3) is a zinc-finger pioneer transcription factor involved in diverse processes. GATA3 regulates gene expression through binding nucleosomal DNA and facilitating chromatin remodelling. Post-translational modifications modulate its activity.
Qiang, Z. +4 more
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LncRNA GATA3-AS1 promotes the proliferation and migration of breast cancer cells and the mechanisms underlying its action [PDF]
Yixue xinzhi zazhi, 2022 Objective Long non-coding RNA (LncRNA) is closely related to the occurrence and development of various tumors. This study aimed to investigate the biological role and mechanism of LncRNA GATA3-AS1 in breast cancer progression.Methods The expression level
Qi JIANG, Yi-Qing XI, Lei WEI
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Transcriptomic analysis and novel insights into lens fibre cell differentiation regulated by Gata3 [PDF]
Open Biology, 2019 Gata3 is a DNA-binding transcription factor involved in cellular differentiation in a variety of tissues including inner ear, hair follicle, kidney, mammary gland and T-cells. In a previous study in 2009, Maeda et al. (Dev. Dyn.
Elena Martynova +4 more
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