Diagnostic and Prognostic Roles of GATA3 Immunohistochemistry in Urothelial Carcinoma
Medicina, 2023 This study aimed to evaluate the diagnostic and prognostic roles of GATA-binding protein 3 (GATA3) immunohistochemistry in urothelial carcinoma (UC) using a meta-analysis.
Daeseon Yoo +3 more
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The molecular basis of T cell acute lymphoblastic leukemia [PDF]
, 2012 T cell acute lymphoblastic leukemias (T-ALLs) arise from the malignant transformation of hematopoietic progenitors primed toward T cell development, as result of a multistep oncogenic process involving constitutive activation of NOTCH signaling and ...
Adolfo Ferrando +23 more
core +1 more source
Urothelial bladder carcinoma metastasizing to the eye: a systematic review and case report [PDF]
, 2019 The eye is a rare site for disseminated malignancies; nevertheless, several tumors may metastasize to ocular structures. Few cases of urothelial and bladder cancer with eye involvement have been described in the literature thus far.
Brunelli, Matteo +12 more
core +1 more source
Epigenetic deregulation of GATA3 in neuroblastoma is associated with increased GATA3 protein expression and with poor outcomes [PDF]
Scientific Reports, 2019 AbstractTo discover epigenetic changes that may underly neuroblastoma pathogenesis, we identified differentially methylated genes in neuroblastoma cells compared to neural crest cells, the presumptive precursors cells for neuroblastoma, by using genome-wide DNA methylation analysis.
Bader Almutairi +6 more
openaire +5 more sources
Variation in phenotypes from a Bmp-Gata3 genetic pathway is modulated by Shh signaling.
PLoS Genetics, 2021 We sought to understand how perturbation of signaling pathways and their targets generates variable phenotypes. In humans, GATA3 associates with highly variable defects, such as HDR syndrome, microsomia and choanal atresia.
Mary E Swartz +2 more
doaj +1 more source
Robust Identification of Target Genes and Outliers in Triple-negative Breast Cancer Data [PDF]
, 2018 Correct classification of breast cancer sub-types is of high importance as it directly affects the therapeutic options. We focus on triple-negative breast cancer (TNBC) which has the worst prognosis among breast cancer types.
Casimiro, Sandra +4 more
core +2 more sources
Immune gene expression profiling of Proliferative Kidney Disease in rainbow trout Oncorhynchus mykiss reveals a dominance of anti-inflammatory, antibody and T helper cell-like activities [PDF]
, 2013 Peer reviewedPublisher ...
Gorgoglione, Bartolomeo +3 more
core +2 more sources
GATA3 Positively Correlates with BCL2 Expression in Indolent and Aggressive Histological Types of Cutaneous Basal Cell Carcinoma [PDF]
Türk Patoloji DergisiObjective: Some histological basal cell carcinoma (BCC) types demonstrate more aggressive behavior than others. They are known as high-risk BCC and are more challenging in therapy, contrary to indolent (low-risk) BCC types.
Fatma Alzahraa Abdelsalam ELKHAMISY +4 more
doaj +1 more source
Type 2 Innate Lymphoid Cells in Allergic Disease. [PDF]
, 2013 Type II innate lymphoid cells (ILC2) are a novel population of lineage-negative cells that produce high levels of Th2 cytokines IL-5 and IL-13. ILC2 are found in human respiratory and gastrointestinal tissue as well as in skin.
Doherty, Taylor A +2 more
core +2 more sources
GATA3 inhibits GCM1 activity and trophoblast cell invasion [PDF]
Scientific Reports, 2016 AbstractDevelopment of human placenta involves the invasion of trophoblast cells from anchoring villi into the maternal decidua. Placental transcription factor GCM1 regulates trophoblast cell invasion via transcriptional activation of HtrA4 gene, which encodes a serine protease enzyme.
Yueh Ho Chiu, Hungwen Chen
openaire +2 more sources