Results 1 to 10 of about 495,118 (275)
Cannabidiol sensitizes TRPV2 channels to activation by 2-APB
eLife, 2023 The cation-permeable TRPV2 channel is important for cardiac and immune cell function. Cannabidiol (CBD), a non-psychoactive cannabinoid of clinical relevance, is one of the few molecules known to activate TRPV2.
Aaron Gochman +5 more
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Frontiers in Computational Neuroscience, 2023 The processing of incoming sensory information can be differentially affected by varying levels of α-power in the electroencephalogram (EEG). A prominent hypothesis is that relatively low prestimulus α-power is associated with improved perceptual ...
Lars T. Boenke +9 more
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eLife, 2022 A long-standing goal in protein science and clinical genetics is to develop quantitative models of sequence, structure, and function relationships to understand how mutations cause disease.
Willow Coyote-Maestas +3 more
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Ion-ing out the genetic variants of Kir2.1
eLife, 2022 Deep mutational scanning provides new insights into how mutations alter the expression and activity of the potassium ion channel Kir2.1, which is associated with many diseases.
Braden S Fallon, Justin G English
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Topography and motion of acid-sensing ion channel intracellular domains
eLife, 2021 Acid-sensing ion channels (ASICs) are trimeric cation-selective channels activated by decreases in extracellular pH. The intracellular N and C terminal tails of ASIC1 influence channel gating, trafficking, and signaling in ischemic cell death.
Tyler Couch +5 more
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Frontiers in Cellular Neuroscience, 2021 Structures of the trimeric acid-sensing ion channel have been solved in the resting, toxin-bound open and desensitized states. Within the extracellular domain, there is little difference between the toxin-bound open state and the desensitized state.
Matthew L. Rook +3 more
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Geography Compass, 2008 Abstract This article examines the notion of gated communities and, more generally, privately governed urban neighbourhoods. We do this by reviewing the idea that they are an innovative built‐environment genre that has spread globally from a diverse set of roots and influences. These include the mass growth of private urban government
Le Goix, Renaud, Webster, Chris
openaire +4 more sources
Клиническая онкогематология, 2021 Detection and monitoring of minimal residual disease (MRD) are essential components of programmed therapy.They are crucial for the choice of treatment strategy and for prognostic purposes practically in all hematologic diseases.
I. V. Galtseva +4 more
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Frontiers in Oncology, 2023 IntroductionPatients treatment compliance increases during free-breathing (FB) treatment, taking generally less time and fatigue with respect to deep inspiration breath-hold (DIBH).
Matteo Galetto +13 more
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Bat use of abandoned mines throughout Nevada
Wildlife Society Bulletin, 2023 Abandoned mines offer important roosting habitat for several species of bats throughout the western United States. Currently, abandoned mine reclamation programs are tasked with closing abandoned mines to ameliorate safety, health, and environmental ...
Megan L. Moran +3 more
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