Results 31 to 40 of about 493,799 (275)

Activity and Ca2+ regulate the mobility of TRPV1 channels in the plasma membrane of sensory neurons

eLife, 2015
TRPV1 channels are gated by a variety of thermal, chemical, and mechanical stimuli. We used optical recording of Ca2+ influx through TRPV1 to measure activity and mobility of single TRPV1 molecules in isolated dorsal root ganglion neurons and cell lines.
Eric N Senning, Sharona E Gordon
doaj   +1 more source

Multi-Talker Speech Promotes Greater Knowledge-Based Spoken Mandarin Word Recognition in First and Second Language Listeners

Frontiers in Psychology, 2020
Spoken word recognition involves a perceptual tradeoff between the reliance on the incoming acoustic signal and knowledge about likely sound categories and their co-occurrences as words.
Seth Wiener, Chao-Yang Lee
doaj   +1 more source

Consonant Recognition Using Coarticulatory Cues in Individuals with Normal Hearing and Sensorineural Hearing Loss

Journal of Indian Speech Language & Hearing Association, 2021
Background and Objectives The study investigated the role of coarticulatory cues in the perception of consonants in Malayalam and its temporal window. It also compared normal hearing individuals and individuals with sensorineural hearing loss (SNHL) for ...
Dhanya Mohan, Sandeep Maruthy
doaj   +1 more source

VAMP721 conformations unmask an extended motif for K+ channel binding and gating control [PDF]

, 2016
Soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins play a major role in membrane fusion and contribute to cell expansion, signaling, and polar growth in plants.
Blatt, Mike R., Donald, Naomi Alice, Karnik, Rucha, Waghmare, Sakharam, Zhang, Ben   +4 more
core   +2 more sources

Membrane mechanics as a probe of ion-channel gating mechanisms [PDF]

, 2008
The details of conformational changes undergone by transmembrane ion channels in response to stimuli, such as electric fields and membrane tension, remain controversial.
Kondev, Jane, Phillips, Rob, Reeves, Daniel, Sens, Pierre, Ursell, Tristan   +4 more
core   +1 more source

Molecular Dynamics Simulations of a Cytochrome P450 from Tepidiphilus thermophilus (P450-TT) Reveal How Its Substrate-Binding Channel Opens

Molecules, 2021
Cytochrome P450s (P450) are important enzymes in biology with useful biochemical reactions in, for instance, drug and xenobiotics metabolisms, biotechnology, and health.
Abayomi S. Faponle, Anupom Roy, Ayodeji A. Adelegan, James W. Gauld   +3 more
doaj   +1 more source

The response of the tandem pore potassium channel TASK-3 (K2P9.1) to voltage : gating at the cytoplasmic mouth [PDF]

, 2009
Although the tandem pore potassium channel TASK-3 is thought to open and shut at its selectivity filter in response to changes of extracellular pH, it is currently unknown whether the channel also shows gating at its inner, cytoplasmic mouth through ...
I. Ashmole, D. V. Vavoulis, P. J. Stansfeld, Puja R. Mehta, J. F. Feng, M. J. Sutcliffe, P. R. Stanfield, Andres-Enguix, Ashmole, Ashmole, Ben-Abu, Bichet, Boeckmann, Brickley, Carter, Chemin, Colquhoun, Colquhoun, Colquhoun, Cordero-Morales, Czirják, Czirják, De La Cruz, Doyle, Duprat, Fanjul, Fersht, Gao, Goldstein, Han, Han, Hidalgo, Horovitz, Jiang, Jiang, Kim, Kim, Kim, Kuo, Leonoudakis, Lopes, Lopes, Lopes, Millar, Morton, Patel, Rajan, Sigworth, Stanfield, Stansfeld, Talley, Talley, Veale, Washburn, Yellen, Yuill, Yuill, Zilberberg   +57 more
core   +1 more source

Phosphorylation-Dependent Regulation of Mammalian Aquaporins

Cells, 2019
Water homeostasis is fundamental for cell survival. Transport of water across cellular membranes is governed by aquaporins—tetrameric integral membrane channels that are highly conserved throughout the prokaryotic and eukaryotic kingdoms.
Veronika Nesverova, Susanna Törnroth-Horsefield   +1 more
doaj   +1 more source

Development and validation of a matlab software program for decoding the treatment errors in real-time position management™ Gating-generated breathing trace

Journal of Medical Physics, 2020
Introduction: The Real-time Position Management™ (RPM) is used as a motion management tool to reduce normal tissue complication. However, no commercial software is available to quantify the “beam-on” errors in RPM-generated breathing traces.
Naveen Kumawat, Anil Kumar Shrotriya, Malhotra Singh Heigrujam, Kartikeswar Patro, Satendra Kumar, Anil Kumar Bansal, Ram Kishan Munjal, Anil Kumar Anand   +7 more
doaj   +1 more source

Voltage Sensing in Bacterial Protein Translocation

Biomolecules, 2020
The bacterial channel SecYEG efficiently translocates both hydrophobic and hydrophilic proteins across the plasma membrane. Translocating polypeptide chains may dislodge the plug, a half helix that blocks the permeation of small molecules, from its ...
Denis G. Knyazev, Roland Kuttner, Ana-Nicoleta Bondar, Mirjam Zimmerman, Christine Siligan, Peter Pohl   +5 more
doaj   +1 more source