Results 61 to 70 of about 283,536 (308)
Alley-gating revisited: the sustainability of resident's satisfaction [PDF]
, 2007 Alleys (snickets, ginnels, backways) are particularly common in British industrial cities and were originally designed to allow access to the rear of properties by coalmen and refuse collectors.
Smithson, Hannah, Armitage, Rachel
core +2 more sources
Structural biology of the TRPM4 channel: architecture, modulation, and therapeutic opportunities
Frontiers in PharmacologyTRPM4 is a Ca2+-activated, monovalent-selective cation channel that conducts Na+ and K+ while remaining essentially impermeable to Ca2+. By translating cytosolic Ca2+ elevations into membrane depolarization rather than additional Ca2+ influx, TRPM4 ...
Ingrid Araya-Durán +6 more
doaj +1 more source
Effects of repetitive practice of motor tasks on somatosensory gating
Frontiers in Human Neuroscience, 2023 IntroductionDuring voluntary muscle contraction, the amplitude of the somatosensory evoked potential (SEP) is reduced by inhibiting sensory information from a peripheral nerve supplying the contracted muscle.
Mayu Akaiwa +5 more
doaj +1 more source
Glutathione accelerates sodium channel inactivation in excised rat axonal membrane patches [PDF]
, 1992 The effects of glutathione were studied on the gating behaviour of sodium channels in membrane patches of rat axons. Depolarizing pulses from –120 to –40 mV elicited sodium currents of up to 500 pA, indicating the simultaneous activation of up to 250 ...
Quasthoff, Stefan +3 more
core +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Frontiers in OncologyBackgroundStereotactic Arrhythmia Radiotherapy (STAR) offers a non-invasive alternative for ventricular tachycardia ablation, yet motion management remains a critical challenge. While respiratory gating is established, cardiac gating requires a dedicated
Nicolas Depauw +21 more
doaj +1 more source
Sensors, 2018 Over two-thirds of a century ago, Hodgkin and Huxley proposed the existence of voltage gated ion channels (VGICs) to carry Na+ and K+ ions across the cell membrane to create the nerve impulse, in response to depolarization of the membrane.
Alisher M. Kariev, Michael E. Green
doaj +1 more source
A pathogenic human Orai1 mutation unmasks STIM1-independent rapid inactivation of Orai1 channels
eLife, 2023 Ca2+ release-activated Ca2+ (CRAC) channels are activated by direct physical interactions between Orai1, the channel protein, and STIM1, the endoplasmic reticulum Ca2+ sensor.
Priscilla S-W Yeung +2 more
doaj +1 more source
High quality testing of grid style power gating [PDF]
, 2014 This paper shows that existing delay-based testing techniques for power gating exhibit fault coverage loss due to unconsidered delays introduced by the structure of the virtual voltage power-distribution-network (VPDN).
Yang, Sheng +9 more
core +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source