Inheritance of the Golgi Apparatus and Cytokinesis Are Controlled by Degradation of GBF1 [PDF]
Cell Reports, 2018 Summary: Although much is known about how chromosome segregation is coupled to cell division, how intracellular organelles partition during mitotic division is poorly understood. We report that the phosphorylation-dependent degradation of the ARFGEF GBF1
Christian Valdes-Quezada +2 more
exaly +6 more sources
Phosphorylation Affects DNA-Binding of the Senescence-Regulating bZIP Transcription Factor GBF1
Plants, 2015 Massive changes in the transcriptome of Arabidopsis thaliana during onset and progression of leaf senescence imply a central role for transcription factors. While many transcription factors are themselves up- or down-regulated during senescence, the bZIP
Ulrike Zentgraf
exaly +4 more sources
Interaction between the triglyceride lipase ATGL and the Arf1 activator GBF1. [PDF]
PLoS ONE, 2011 The Arf1 exchange factor GBF1 (Golgi Brefeldin A resistance factor 1) and its effector COPI are required for delivery of ATGL (adipose triglyceride lipase) to lipid droplets (LDs).
Emy Njoh Ellong +5 more
doaj +4 more sources
Combined Transcriptomic and Metabolomic Analysis Reveals an Ethylene‐Activated Regulatory Model on Monoterpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus [PDF]
Plant Biotechnology Journal, Volume 24, Issue 2, Page 363-380, February 2026.ABSTRACT Catharanthus roseus contains nearly 200 bioactive monoterpenoid indole alkaloids (MIAs) that are effective in treating cancer and other diseases. Ethylene plays a significant role in enhancing MIA biosynthesis, and we have found that it greatly induces the accumulation of anhydrovinblastine.
Bofu Deng +9 more
wiley +2 more sources
Disease‐Associated Factors at the Endoplasmic Reticulum–Golgi Interface [PDF]
Traffic, Volume 26, Issue 1-3, January/March 2025.The ER–Golgi interface has garnered significant attention due to recent discoveries suggesting potential non‐vesicular transport mechanisms and regulation through liquid‐liquid phase separation. Numerous diseases linked to mutations in proteins located at this interface have been identified, highlighting the importance of comprehensive reviews in this ...
Miharu Maeda +2 more
wiley +2 more sources
Acute GARP Depletion Disrupts Vesicle Transport, Leading to Severe Defects in Sorting, Secretion and O‐Glycosylation [PDF]
Traffic, Volume 26, Issue 1-3, January/March 2025.Cartoon illustrating defects caused by GARP dysfunction. (Left) Control cells exhibit normal Golgi morphology with a stratified distribution of enzymes and trafficking machinery. (Right) Following acute VPS54 depletion, vesicle numbers increase, the trans‐Golgi enlarges, endosome‐Golgi trafficking proteins mislocalize to vesicles, and Golgi association
Amrita Khakurel +3 more
wiley +2 more sources
Toxoplasma and Plasmodium associate with host Arfs during infection [PDF]
mSphereThe apicomplexans Toxoplasma gondii and Plasmodium are intracellular parasites that reside within a host-derived compartment termed the parasitophorous vacuole (PV).
Erin A. Schroeder +5 more
doaj +2 more sources
Kinetics of Arf1 inactivation regulates Golgi organisation and function in non-adherent fibroblasts [PDF]
Biology Open, 2023 Rajeshwari B.R. +4 more
doaj +2 more sources
Src activates retrograde membrane traffic through phosphorylation of GBF1
eLife, 2021 The Src tyrosine kinase controls cancer-critical protein glycosylation through Golgi to ER relocation of GALNTs enzymes. How Src induces this trafficking event is unknown.
Joanne Chia +8 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Bone-resorbing activities of osteoclasts (OCs) are highly dependent on actin cytoskeleton remodeling, plasma membrane reorganization, and vesicle trafficking pathways, which are partially regulated by ARF-GTPases.
Cailing Wen +12 more
doaj +1 more source