Skeletal muscle perilipin 3 and coatomer proteins are increased following exercise and are associated with fat oxidation. [PDF]
PLoS ONE, 2014 Lipid droplet-associated proteins such as perilipin 3 (PLIN3) and coatomer GTPase proteins (GBF1, ARF1, Sec23a, and ARFRP1) are expressed in skeletal muscle but little is known so far as to their regulation of lipolysis.
Jeffrey D Covington +7 more
doaj +1 more source
Hijacking of multiple phospholipid biosynthetic pathways and induction of membrane biogenesis by a picornaviral 3CD protein. [PDF]
PLoS Pathogens, 2018 RNA viruses induce specialized membranous structures for use in genome replication. These structures are often referred to as replication organelles (ROs). ROs exhibit distinct lipid composition relative to other cellular membranes.
Sravani Banerjee +10 more
doaj +1 more source
The AtCathB3 gene, encoding a cathepsin B-like protease, is expressed during germination of Arabidopsis thaliana and transcriptionally repressed by the basic leucine zipper protein GBF1. [PDF]
, 2013 Protein hydrolysis plays an important role during seed germination and post-germination seedling establishment. In Arabidopsis thaliana, cathepsin B-like proteases are encoded by a gene family of three members, but only the AtCathB3 gene is highly ...
Barrero-Sicilia, C. +16 more
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GBF1 recruitment to membranes: domains and interacting proteins
, 2020 The Golgi complex resides at the center of the cellular trafficking pathway, where it functions in the modification, sorting, and trafficking of over one third of human proteins to their correct cellular destination.
Chan, Calvin J
core +1 more source
Analysis of 12 GWAS-Linked Loci With Parkinson’s Disease in the Chinese Han Population
Frontiers in Neurology, 2021 A recent large-scale European-originated genome-wide association study identified 38 novel independent risk signals in 37 loci for Parkinson's disease (PD). However, whether these new loci are associated with PD in Asian populations remains elusive.
Liyuan Fan +33 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2022 Golgi-associated retrograde protein (GARP) is an evolutionary conserved heterotetrameric protein complex that tethers endosome-derived vesicles and is vital for Golgi glycosylation. Microscopy and proteomic approaches were employed to investigate defects
Amrita Khakurel +4 more
doaj +1 more source
Molecular determinants of the interaction between coxsackievirus protein 3A and guanine nucleotide exchange factor GBF1. [PDF]
, 2007 Contains fulltext : 52098.pdf (Publisher’s version ) (Open Access)The 3A protein of coxsackievirus B3 (CVB3), a small membrane protein that forms homodimers, inhibits endoplasmic reticulum-to-Golgi complex transport.
Melchers, W.J.G. +11 more
core +2 more sources
F1000Research, 2020 Invertebrate glia performs most of the key functions controlled by mammalian glia in the nervous system and provides an ideal model for genetic studies of glial functions.
Catarina Gonçalves-Pimentel +5 more
doaj +1 more source
ARF1 and GBF1 generate a PI4P-enriched environment supportive of hepatitis C virus replication. [PDF]
PLoS ONE, 2012 Cellular levels of phosphatidylinositol 4-phosphate (PI4P) have been shown to be upregulated during RNA replication of several viruses, including the HCV replicon model.
Leiliang Zhang +6 more
doaj +1 more source
GBF1 is required for EV71 replication.
, 2014 (A) Targeted siRNAs could effectively knockdown the expression of each GEF ...
Qi Jin (12159) +2 more
core +1 more source