Results 51 to 60 of about 1,805 (175)

Analysis of 12 GWAS-Linked Loci With Parkinson’s Disease in the Chinese Han Population

open access: yesFrontiers in Neurology, 2021
A recent large-scale European-originated genome-wide association study identified 38 novel independent risk signals in 37 loci for Parkinson's disease (PD). However, whether these new loci are associated with PD in Asian populations remains elusive.
Liyuan Fan   +33 more
doaj   +1 more source

Chlamydia trachomatis co-opts GBF1 and CERT to acquire host sphingomyelin for distinct roles during intracellular development. [PDF]

open access: yesPLoS Pathogens, 2011
The strain designated Chlamydia trachomatis serovar that was used for experiments in this paper is Chlamydia muridarum, a species closely related to C. trachomatis (and formerly termed the Mouse Pneumonitis strain of C. trachomatis. [corrected].
Cherilyn A Elwell   +7 more
doaj   +1 more source

A miRNA screen procedure identifies garz as an essential factor in adult glia functions and validates Drosophila as a beneficial 3Rs model to study glial functions and GBF1 biology [version 1; peer review: 2 approved]

open access: yesF1000Research, 2020
Invertebrate glia performs most of the key functions controlled by mammalian glia in the nervous system and provides an ideal model for genetic studies of glial functions.
Catarina Gonçalves-Pimentel   +5 more
doaj   +1 more source

ARF1 and GBF1 generate a PI4P-enriched environment supportive of hepatitis C virus replication. [PDF]

open access: yesPLoS ONE, 2012
Cellular levels of phosphatidylinositol 4-phosphate (PI4P) have been shown to be upregulated during RNA replication of several viruses, including the HCV replicon model.
Leiliang Zhang   +6 more
doaj   +1 more source

A miRNA screen procedure identifies garz as an essential factor in adult glia functions and validates Drosophila as a beneficial 3Rs model to study glial functions and GBF1 biology [version 2; peer review: 2 approved]

open access: yesF1000Research, 2020
Invertebrate glia performs most of the key functions controlled by mammalian glia in the nervous system and provides an ideal model for genetic studies of glial functions.
Catarina Gonçalves-Pimentel   +5 more
doaj   +1 more source

GBF1 is required for EV71 replication.

open access: yes, 2014
(A) Targeted siRNAs could effectively knockdown the expression of each GEF ...
Qi Jin (12159)   +2 more
core   +1 more source

Molecular determinants of the interaction between coxsackievirus protein 3A and guanine nucleotide exchange factor GBF1. [PDF]

open access: yes, 2007
Contains fulltext : 52098.pdf (Publisher’s version ) (Open Access)The 3A protein of coxsackievirus B3 (CVB3), a small membrane protein that forms homodimers, inhibits endoplasmic reticulum-to-Golgi complex transport.
Melchers, W.J.G.   +11 more
core   +1 more source

GBF1 sequence determines BFA resistance of cells and virus.

open access: yes, 2013
A. Sequencing chromatograms of GBF1 Sec7 domain from Vero and BER-40 cells. Results from analyses with three different primers are shown. B. GBF1 A795E mutant confers BFA resistance to HeLa cells.
George A. Belov (375765)   +4 more
core   +1 more source

Poliovirus replication requires the N-terminus but not the catalytic Sec7 domain of ArfGEF GBF1 [PDF]

open access: yesCellular Microbiology, 2010
Viruses are intracellular parasites whose reproduction relies on factors provided by the host. The cellular protein GBF1 is critical for poliovirus replication. Here we show that the contribution of GBF1 to virus replication is different from its known activities in uninfected cells.
Belov, George A.   +3 more
openaire   +2 more sources

Infectious Bursal Disease Virus Assembly Causes Endoplasmic Reticulum Stress and Lipid Droplet Accumulation

open access: yesViruses, 2023
Gumboro illness is caused by the highly contagious immunosuppressive infectious bursal disease virus (IBDV), which affects the poultry industry globally.
Yesica R. Frontini-López   +6 more
doaj   +1 more source

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