Results 61 to 70 of about 1,851 (152)

Identification de GBF1, un facteur cellulaire nécessaire à la réplication du virus de l'hépatite E

, 2018
International audienceThe hepatitis E virus (HEV) genome is a single‐stranded, positive‐sense RNA that encodes three proteins including the ORF1 replicase.
Jackson, Catherine, L, Moradpour, D., Jackson, Catherine,, Jackson, C.L., Rouillé, Y., Ankavay, M., Dubuisson, J., Dubuisson, Jean, Lebsir, N., Moradpour, Darius, Cocquerel, L., Lebsir, Nadjet, Ankavay, Maliki, Rouillé, Yves, Farhat, Rayan, Wychowski, Czeslaw, Farhat, R., Gouttenoire, Jérôme, Wychowski, C., Gouttenoire, J., Cocquerel, Laurence   +20 more
core   +1 more source

Unequal Genetic Redundancies Among MYC bHLH Transcription Factors Underlie Seedling Photomorphogenesis in Arabidopsis

Plant Direct, Volume 9, Issue 2, February 2025.
ABSTRACT Light is one of the most critical ecological cues controlling plant growth and development. Plants have evolved complex mechanisms to cope with fluctuating light signals. In Arabidopsis, bHLH transcription factors MYC2, MYC3, and MYC4 have been shown to play a vital role in protecting plants against herbivory and necrotrophic pathogens.
Vikas Garhwal, Sreya Das, Sreeramaiah N. Gangappa   +2 more
wiley   +1 more source

Streptococcus pneumoniae disrupts the structure of the golgi apparatus and subsequent epithelial cytokine response in an H2O2-dependent manner

Cell Communication and Signaling, 2023
Background Lung infections caused by Streptococcus pneumonia are a global leading cause of death. The reactive oxygen species H2O2 is one of the virulence factors of Streptococcus pneumoniae. The Golgi apparatus is essential for the inflammatory response
Björn Klabunde, André Wesener, Wilhelm Bertrams, Stephan Ringshandl, Luke D. Halder, Evelyn Vollmeister, Bernd Schmeck, Birke J. Benedikter   +7 more
doaj   +1 more source

Functional relationship of GBF1 with HY5 and HYH in genome-wide gene expression in Arabidopsis

, 2016
Transcriptional networks play important roles in the regulation of biological processes through coordinated activation or repression of downstream target genes.
Singh, Aparna, Ram, Hathi, Jain, Mukesh, Chattopadhyay, Sudip   +3 more
core   +1 more source

GBF1 and Arf1 interact with Miro and regulate mitochondrial positioning within cells. [PDF]

, 2018
The spatial organization of cells depends on coordination between cytoskeletal systems and intracellular organelles. The Arf1 small G protein and its activator GBF1 are important regulators of Golgi organization, maintaining its morphology and function ...
Walch, Laurence, Gautreau, A., Contremoulins, V., Contremoulins, Vincent, Verbavatz, J., Pellier, Emilie, Jackson, Catherine, Walch, L., Pellier, E., Jackson, C., Gautreau, Alexis, Lakisic, Goran, Lakisic, G., Verbavatz, Jean-Marc, Leng, W., Leng, Weihua   +15 more
core   +1 more source

Structural Insights into Arl1-Mediated Targeting of the Arf-GEF BIG1 to the trans-Golgi

Cell Reports, 2016
The GTPase Arf1 is the major regulator of vesicle traffic at both the cis- and trans-Golgi. Arf1 is activated at the cis-Golgi by the guanine nucleotide exchange factor (GEF) GBF1 and at the trans-Golgi by the related GEF BIG1 or its paralog, BIG2.
Antonio Galindo, Nicolas Soler, Stephen H. McLaughlin, Minmin Yu, Roger L. Williams, Sean Munro   +5 more
doaj   +1 more source

Phosphorylation and membrane dissociation of the ARF exchange factor GBF1 in mitosis [PDF]

, 2010
Secretory protein trafficking is arrested and the Golgi apparatus fragmented when mammalian cells enter mitosis. These changes are thought to facilitate cell-cycle progression and Golgi inheritance, and are brought about through the actions of ...
Balklava, Zita, Balklava, Z, Ball, Matthew, Morohashi, Yuichi, Hughes, Helen, Lowe, Martin, Lowe, M, Lowe, Martin; id_orcid, Hughes, H, Morohashi, Y, Ball, M   +10 more
core   +1 more source

Chlamydia trachomatis co-opts GBF1 and CERT to acquire host sphingomyelin for distinct roles during intracellular development.

PLoS Pathogens, 2011
The strain designated Chlamydia trachomatis serovar that was used for experiments in this paper is Chlamydia muridarum, a species closely related to C. trachomatis (and formerly termed the Mouse Pneumonitis strain of C. trachomatis. [corrected].
Cherilyn A Elwell, Shaobo Jiang, Jung Hwa Kim, Albert Lee, Torsten Wittmann, Kentaro Hanada, Paul Melancon, Joanne N Engel   +7 more
doaj   +1 more source

Synoptic Variation Drives Genetic Diversity and Transmission Mode of Airborne DNA Viruses in Urban Space

Advanced Science, Volume 11, Issue 46, December 11, 2024.
Airborne viral communities are influenced by weather conditions with highly prevalent Caudoviricetes in cloudy/smoggy air and Repensiviricetes in sunny/rainy air, revealing different transmission modes under various air quality conditions. They carry diverse auxiliary metabolic genes mainly for the synthesis of nucleotide sugars, dNDP/dNTP, and ...
Aihua Deng, Junyue Wang, Lai Li, Ruilin Shi, Xuemin Li, Tingyi Wen   +5 more
wiley   +1 more source

Generation of Unique Poliovirus RNA Replication Organelles

mBio, 2014
Poliovirus (PV), a model for interactions of picornaviruses with host cells, replicates its genomic RNA in association with cellular membranes. The origin of PV replication membranes has not been determined.
Alexsia L. Richards, Jamária A. P. Soares-Martins, Geoffrey T. Riddell, William T. Jackson   +3 more
doaj   +1 more source