Results 61 to 70 of about 1,805 (175)

SWEET1‐mediated glucose transport is crucial for energy availability in Arabidopsis

New Phytologist, Volume 249, Issue 4, Page 1816-1830, February 2026.
Summary The stress‐responsive hormone abscisic acid (ABA) is known for its inhibitory effects on various physiological processes, including seed germination, often resulting in energy deprivation. Interestingly, ABA‐induced germination inhibition can be alleviated by exogenous glucose (Glc), mimicking a functional interplay between ABA and sugar ...
Xueyi Xue, Jiankun Li, Ya‐Chi Yu, Li‐Qing Chen   +3 more
wiley   +1 more source

ARF1 recruits RAC1 to leading edge in neutrophil chemotaxis

Cell Communication and Signaling, 2017
Background The small GTPase ARF1 mediates membrane trafficking mostly from the Golgi, and is essential for the G protein-coupled receptor (GPCR)-mediated chemotaxis of neutrophils.
Yuichi Mazaki, Yasuhito Onodera, Tsunehito Higashi, Takahiro Horinouchi, Tsukasa Oikawa, Hisataka Sabe   +5 more
doaj   +1 more source

De Novo and Inherited Variants in GBF1 are Associated with Axonal Neuropathy Caused by Golgi Fragmentation [PDF]

The American Journal of Human Genetics, 2020
Distal hereditary motor neuropathies (HMNs) and axonal Charcot-Marie-Tooth neuropathy (CMT2) are clinically and genetically heterogeneous diseases characterized primarily by motor neuron degeneration and distal weakness. The genetic cause for about half of the individuals affected by HMN/CMT2 remains unknown.
Mendoza-Ferreira, Natalia, Karakaya, Mert, Cengiz, Nur, Beijer, Danique, Brigatti, Karlla W., Gonzaga-Jauregui, Claudia, Fuhrmann, Nico, Hölker, Irmgard, Thelen, Maximilian P., Zetzsche, Sebastian, Rombo, Roman, Puffenberger, Erik G., De Jonghe, Peter, Deconinck, Tine, Zuchner, Stephan, Strauss, Kevin A., Carson, Vincent, Schrank, Bertold, Wunderlich, Gilbert, Baets, Jonathan, Wirth, Brunhilde   +20 more
openaire   +3 more sources

BML-265 and Tyrphostin AG1478 Disperse the Golgi Apparatus and Abolish Protein Transport in Human Cells

Frontiers in Cell and Developmental Biology, 2019
The steady-state localization of Golgi-resident glycosylation enzymes in the Golgi apparatus depends on a balance between anterograde and retrograde transport.
Gaelle Boncompain, Nelly Gareil, Sarah Tessier, Aurianne Lescure, Thouis R. Jones, Oliver Kepp, Oliver Kepp, Guido Kroemer, Guido Kroemer, Guido Kroemer, Guido Kroemer, Guido Kroemer, Elaine Del Nery, Franck Perez   +13 more
doaj   +1 more source

The ArfGEF GBF-1 Is Required for ER Structure, Secretion and Endocytic Transport in C. elegans. [PDF]

PLoS ONE, 2013
Small GTPases of the Sar/Arf family are essential to generate transport containers that mediate communication between organelles of the secretory pathway.
Karin B Ackema, Ursula Sauder, Jachen A Solinger, Anne Spang   +3 more
doaj   +1 more source

Class I ADP-ribosylation factors are involved in enterovirus 71 replication.

PLoS ONE, 2014
Enterovirus 71 is one of the major causative agents of hand, foot, and mouth disease in infants and children. Replication of enterovirus 71 depends on host cellular factors.
Jianmin Wang, Jiang Du, Qi Jin
doaj   +1 more source

Correlation Between the Evolution of Somatic Alterations During Lymphatic Metastasis and Clinical Outcome in Penile Squamous Cell Carcinoma

Frontiers in Oncology, 2021
Penile squamous cell carcinoma (PSCC) is a rare malignancy with poor survival after standard treatment. Although genomic alterations of PSCC have been characterized in several latest studies, the association between the formation of somatic landscape and
Jian Cao, Chun-He Yang, Wei-Qing Han, Yu Xie, Zhi-Zhong Liu, Shu-Suan Jiang   +5 more
doaj   +1 more source

Guanine Nucleotide Exchange Factors and Small GTPases: Their Regulation and Functions, Diseases, and Therapeutic Targets

MedComm, Volume 6, Issue 10, October 2025.
This review comprehensively examines the regulatory mechanisms and physiological roles of guanine nucleotide exchange factors (GEFs) and their small GTPase substrates, highlighting their significance in cellular processes and disease pathogenesis.
Zexing Lin, Chujun Ni, Haiyang Jiang, Huan Yang, Liting Deng, Peizhao Liu, Xuanheng Li, Yilong Yu, Weijie Li, Runnan Wang, Bo Liao, Jiaqi Kang, Juanhan Liu, Xiuwen Wu, Jianan Ren, Yun Zhao   +15 more
wiley   +1 more source

Recruitment of PI4KIIIβ to Coxsackievirus B3 Replication Organelles Is Independent of ACBD3, GBF1, and Arf1 [PDF]

Journal of Virology, 2014
ABSTRACT Members of the Enterovirus (poliovirus [PV], coxsackieviruses, and human rhinoviruses) and Kobuvirus (Aichi virus) genera in the Picornaviridae family rely on PI4KIIIβ (phosphatidylinositol-4-kinase IIIβ) for efficient replication. The small membrane-
Dorobantu, Cristina M, van der Schaar, Hilde M, Ford, Lauren A, Strating, Jeroen R P M, Ulferts, Rachel, Fang, Ying, Belov, George, van Kuppeveld, Frank J M   +7 more
openaire   +4 more sources

A membrane fusion protein αSNAP is a novel regulator of epithelial apical junctions. [PDF]

PLoS ONE, 2012
Tight junctions (TJs) and adherens junctions (AJs) are key determinants of the structure and permeability of epithelial barriers. Although exocytic delivery to the cell surface is crucial for junctional assembly, little is known about the mechanisms ...
Nayden G Naydenov, Bryan Brown, Gianni Harris, Michael R Dohn, Victor M Morales, Somesh Baranwal, Albert B Reynolds, Andrei I Ivanov   +7 more
doaj   +1 more source