Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Identification of the key aroma-active compounds in wolfberry (Lycium barbarum L.) pulp
Identifying the key aroma-active compounds in wolfberry pulp is essential for ensuring product quality. In this study, the key odorants in fresh wolfberry pulp (FWP), dried wolfberry pulp (DWP) and mixed wolfberry pulp (MWP) were systematically ...
Zhifeng Zhang +6 more
doaj +1 more source
Does aroma composition allow to discriminate groups of dark chocolates categorized on the basis of their organoleptic properties? Inputs of direct injection Mass spectrometry (PTR-TOF-MS) and GC-OLFAC [PDF]
Organoleptic properties and particularly aroma of dark chocolate depend on cocoa origin, cocoa variety and fabrication process. A sensory analysis performed on 206 dark chocolates produced from cocoa beans of different varieties and origins but with the ...
Andriot, Isabelle +3 more
core
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
The aim of this study is the aromatic characterization of new table grape varieties, namely Guzun (V. vinifera), Melona (V. vinifera), Cotton Candy (V. vinifera), IVC SA3 (V. labrusca), and IVC SB1 (V. labrusca). The qualitative and quantitative analysis
Federica Bonello +8 more
doaj +1 more source
The objectives of the review are the collection, concise description and evaluation of the various chromatographic techniques used for the separation and quantitative determination of macro- and microcomponents present in ...
Cserháti, Tibor, Szőgyi, Mária
core
Fused silica capillary interferometer with a layer-by-layer functional coating for the analysis of chemicals content in aqueous solutions [PDF]
A simple fused silica capillary interferometric (FSCI) sensor has been proposed and investigated for the detection and analysis of multiple chemical compounds content in aqueous solutions.
Brambilla, Gilberto +6 more
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Komponen Flavor Volatil Tempe yang Dibungkus dengan Daun Pisang dan Plastik
The objective of the research was to identify volatile flavor compounds and odor description of tempeh wrapped with banana leaf and plastic fermented at different times. The research object was tempeh wrapped with banana leaf (TD) at 48 (TD1H), 72 (TD2H),
Rasyid Hanafi Harahap +2 more
doaj +1 more source
Asymptotically conical Ricci-flat Kahler metrics with cone singularities [PDF]
The main result proved in this thesis is an existence theorem for asymptotically conical Ricci-flat Kahler metrics on C2 with cone singularities along a smooth complex curve.
de Borbon, Gonzalo Martin
core +1 more source

