Results 121 to 130 of about 12,946 (215)

Retrospective examination of pediatric patients followed with the diagnosis of monogenic diabetes type 2 (mody type 2-GCK)

, 2022
Gençlikte ortaya çıkan erişkin tip diyabet (MODY), tek gende meydana gelen otozomal dominant mutasyonlar nedeniyle pankreas β hücrelerinde fonksiyon bozukluğuna yol açan diyabet formudur. Günümüzde MODY’ye yol açan 14 farklı gen mutasyonu tanımlanmıştır.
Tula, Burak
core  

GCK gene-body hypomethylation is associated with the risk of coronary heart disease. Biomed Res Int

, 2020
Objectives. Glucokinase encoded by GCK is a key enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate. Variants of GCK gene were shown to be associated with type 2 diabetes (T2D) and coronary heart disease (CHD).
Lina Zhang, Xinbao Shi, Yi Huang, Zhaoyang Wang, Dawei Zheng, Lebo Sun, Shiwei Duan, Limin Xu, Meng Ye, Qingyun Zhou, Guofeng Shao, Haibo Liu, Panpan Liu, Ni Li, Leiting Xu, Yanping Le, Danjie Jiang, Lingyan Wang, Qi Liao   +18 more
core  

Co-occurrence of Loss-of-Function GCK and ABCC8 Variants in a Pedigree With a Spectrum of Dysglycemia. [PDF]

Diabetes
Saint-Martin C, ElSheikh A, Jacqueminet S, Arnoux JB, Ciangura C, Bellanné-Chantelot C, Shyng SL.   +6 more
europepmc   +1 more source

Influence of Light Quality During Spreading on the Chemical and Aromatic Profile of Summer Green Tea. [PDF]

Int J Mol Sci
Xia X, Lin L, Xu F, Liu Y, Zhao Y, Xu W.
europepmc   +1 more source

Personalized management of glucokinase-related monogenic diabetes (GCK-MODY) during pregnancy: a case report. [PDF]

Front Endocrinol (Lausanne)
Bolas AF, Torres JO, Bogalho P, Silva-Nunes J.   +3 more
europepmc   +1 more source

Morning Elevation in Insulin Enhances Afternoon Hepatic Glucose Disposal in Dogs by Increasing Both Insulin Signaling and Glucose Action. [PDF]

Diabetes
Waterman HL, Smith MS, Farmer B, Yankey K, Howard T, Kraft G, Cherrington AD, Edgerton DS.   +7 more
europepmc   +1 more source

Classification of <i>GCK</i>-MODY in a child with mild hyperglycemia and islet autoantibody positivity: a diagnostic challenge. [PDF]

JCEM Case Rep
Yarlagadda AN, Redondo MJ, Pollin TI, Tosur M, Jodarski CO, Bell JJ.   +5 more
europepmc   +1 more source

Case Report: A novel likely pathogenic <i>GCK</i> variant in a young Chinese girl with severe insulin resistance. [PDF]

Front Endocrinol (Lausanne)
Bai H, Yu J, Wang T, Ren J, Shao C, Zhang Q, Xiao X.   +6 more
europepmc   +1 more source

Cost Effectiveness of GCK-MODY Genetic Screening for Selected Individuals Referred to the Diabetes Prevention Programme

MODY accounts for 1 5% of diabetes cases, of these GCK-MODY comprises approximately 30%.GCKMODY is associated with minimal risk of complications. Efficiently diagnosing GCK-MODY leads to more appropriate management and resource allocation.
Noble, Jane, Ng, N., Lockhart, M., Divilly, P.   +3 more
core  

Treatment Options for Patients with Maturity-Onset Diabetes of the Young (MODY): A Systematic Review of Literature: 2026 Update. [PDF]

Diabetes Ther
Zagaroli L, Di Berardino A, Petragnano F, Lustri S, Fasciani I, Rossi M, Baroni MG, Delvecchio M.   +7 more
europepmc   +1 more source