Grass carp reovirus VP56 and VP35 induce formation of viral inclusion bodies for replication. [PDF]
Zhang C, Wu H, Feng H, Zhang YA, Tu J.
europepmc +1 more source
Unveiling the impact of non-coding RNAs on virus-induced cellular autophagy: roles and research advances. [PDF]
Yu M, Yi Y, Yang H, Zhang Y.
europepmc +1 more source
A deep dive into ferritin nanoparticle advancements: experimental and computational perspectives. [PDF]
Rezaei E, Azimzadeh Irani M.
europepmc +1 more source
A zebrafish NLRX1 isoform downregulates fish IFN responses by targeting the adaptor STING. [PDF]
Zhao X +8 more
europepmc +1 more source
Oral Vaccination of Grass Carp (Ctenopharyngodon idella) with Baculovirus-Expressed Grass Carp Reovirus (GCRV) Proteins Induces Protective Immunity against GCRV Infection [PDF]
The grass carp reovirus (GCRV) causes severe hemorrhagic disease with high mortality and leads to serious economic losses in the grass carp (Ctenopharyngodon idella) industry in China. Oral vaccine has been proven to be an effective method to provide protection against fish viruses.
Lingbing Zeng +2 more
exaly +4 more sources
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Autophagy signaling pathway is a therapeutic target to inhibit GCRV replication
Aquaculture, 2022Abstract Autophagy is an evolutionarily conserved process that is thought to be essential for maintaining physiological homeostasis. However, the role of autophagy in host immune defense against viruses was poorly understood in fish. In this study, we found that although GCRV infection induced autophagy, increasing autophagy level by rapamycin ...
Pengfei Chu, Libo He
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RNA-seq profiles from grass carp tissues after reovirus (GCRV) infection based on singular and modular enrichment analyses [PDF]
Hemorrhagic disease of the grass carp, Ctenopharyngodon idella, is a fatal disease in fingerlings and yearlings caused by a reovirus, GCRV. RNA-seq data from four diseased grass carp tissues (gill, intestine, liver and spleen) were obtained at 2 h before
Mijuan Shi, Zuoyan Zhu, Lanjie Liao
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Functions of MDA5 and its domains in response to GCRV or bacterial PAMPs
Fish and Shellfish Immunology, 2015Melanoma differentiation-associated gene 5 (MDA5) is a member of retinoic acid-inducible gene I (RIG-I)-like receptor (RLR) family which can initiate type I IFN expression in response to RNA virus infection. In this study, we constructed six mutants of Ctenopharyngodon idella MDA5 (CiMAD5) overexpression plasmids and generated stable transfected C ...
Lijun Chen, Jianguo Su, Youliang Rao
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