Results 151 to 160 of about 912 (176)
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Developmental & Comparative Immunology, 2023
Studies on host immunity evasion by aquatic viruses have largely focused on coding genes. There is accumulating evidence for the important biological functions of non-coding miRNAs in virus-host interactions. The regulatory functions of non-coding miRNAs in fish reovirus-host interactions remain unknown.
Yangyu Li +9 more
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Studies on host immunity evasion by aquatic viruses have largely focused on coding genes. There is accumulating evidence for the important biological functions of non-coding miRNAs in virus-host interactions. The regulatory functions of non-coding miRNAs in fish reovirus-host interactions remain unknown.
Yangyu Li +9 more
openaire +2 more sources
Aquaculture, 2021
Abstract Grass carp reovirus (GCRV) is a causing pathogen of grass carp hemorrhagic disease, whose outbreak often brings out a huge economic loss in aquaculture filed. Cellular lipids play crucial roles in many biological processes, such as virus replication, maturation and transmission. Presently, it remains to elucidate the roles of these lipids in
Xing Zhang +7 more
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Abstract Grass carp reovirus (GCRV) is a causing pathogen of grass carp hemorrhagic disease, whose outbreak often brings out a huge economic loss in aquaculture filed. Cellular lipids play crucial roles in many biological processes, such as virus replication, maturation and transmission. Presently, it remains to elucidate the roles of these lipids in
Xing Zhang +7 more
openaire +1 more source
Fish & Shellfish Immunology, 2016
Triploid hybrid of gold fish (Carassius auratus red var., ♀, 2n = 100) and allotetroploid (♂, 2n = 100) displays much improved disease resistance than its parents. In this paper, one of the type I IFNs of triploid hybrid (3nIFNa) has been cloned and characterized.
Jun, Yan +6 more
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Triploid hybrid of gold fish (Carassius auratus red var., ♀, 2n = 100) and allotetroploid (♂, 2n = 100) displays much improved disease resistance than its parents. In this paper, one of the type I IFNs of triploid hybrid (3nIFNa) has been cloned and characterized.
Jun, Yan +6 more
openaire +2 more sources
Ctenopharyngodon idellus DDX41 initiates IFN I and ISG15 expression in response to GCRV infection
Fish & Shellfish Immunology, 2020As a member of DExD/H-box helicase family, DDX41 (DEAD box polypeptide 41) acts as an intracellular DNA sensor that induces type I IFN expression in mammals. Fish DDX41 shares some similar properties with the mammalian counterparts. In this study, a DDX41 orthologous gene from grass carp (Ctenopharyngodon idellus) (CiDDX41) was cloned and characterized.
Jihuan, Hu +3 more
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Fish & Shellfish Immunology
The complement system, a critical component of innate immunity in fish, plays a pivotal role in the defense against Grass Carp Reovirus (GCRV) infection in grass carp. This study explores the structural characteristics of C1S, a crucial molecule in the classical pathway of the complement system, and its involvement in the response to GCRV infection. We
Yuling Wei +3 more
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The complement system, a critical component of innate immunity in fish, plays a pivotal role in the defense against Grass Carp Reovirus (GCRV) infection in grass carp. This study explores the structural characteristics of C1S, a crucial molecule in the classical pathway of the complement system, and its involvement in the response to GCRV infection. We
Yuling Wei +3 more
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Archives of Virology
Grass carp reovirus is a major aquaculture biosecurity threat, causing acute outbreaks and diagnostic delays in hemorrhagic disease. For early warning of GCRV-II in aquaculture water, this study established a method using iron flocculation to concentrate viruses, with qPCR-based tracking and viral load quantification. Results show the S7 gene serves as
Ying Zhan +4 more
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Grass carp reovirus is a major aquaculture biosecurity threat, causing acute outbreaks and diagnostic delays in hemorrhagic disease. For early warning of GCRV-II in aquaculture water, this study established a method using iron flocculation to concentrate viruses, with qPCR-based tracking and viral load quantification. Results show the S7 gene serves as
Ying Zhan +4 more
openaire +2 more sources
In Vitro and In Vivo Antiviral Activity of Histone Deacetylase Inhibitors Against
ABSTRACT Grass carp haemorrhagic disease (GCHD), a severe viral affliction caused by grass carp reovirus (GCRV), is responsible for significant mortality among grass carp. Characterised by rapid transmission and latent infections, GCHD poses a critical challenge in aquaculture.
Guangyao Hu +6 more
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Fish & Shellfish Immunology, 2017
Sterile triploid hybrids (3n = 150) of gold fish (Carassius auratus red var., ♀, 2n = 100) and allotetroploid (♂, 2n = 100) display obviously improved disease resistance and much enhanced growth rate than their parents, which have been cultured widely in China.
Jun, Yan +6 more
openaire +2 more sources
Sterile triploid hybrids (3n = 150) of gold fish (Carassius auratus red var., ♀, 2n = 100) and allotetroploid (♂, 2n = 100) display obviously improved disease resistance and much enhanced growth rate than their parents, which have been cultured widely in China.
Jun, Yan +6 more
openaire +2 more sources
CiLSM14Aa acts as a cytosolic dsRNA sensor to activate antiviral immunity against GCRV-II
Fish & Shellfish ImmunologyThe innate immune system relies on pattern recognition receptors (PRRs) to detect viral pathogens and initiate antiviral responses. LSM14A, a conserved RNA-binding protein involved in mRNA metabolism, has recently emerged as a cytosolic nucleic acid sensor in vertebrates. However, its role in teleost immunity remains unclear.
Hui Jiang +4 more
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Evaluation of immune efficacy of GCRV vp6 DNA vaccine
Journal of Fishery Sciences of China, 2013Lin LIU +9 more
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