Results 151 to 160 of about 909 (176)
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The structural characteristics and expression characteristics of C1S in response to GCRV infection in grass carp

Fish & Shellfish Immunology
The complement system, a critical component of innate immunity in fish, plays a pivotal role in the defense against Grass Carp Reovirus (GCRV) infection in grass carp. This study explores the structural characteristics of C1S, a crucial molecule in the classical pathway of the complement system, and its involvement in the response to GCRV infection. We
Yuling Wei   +3 more
openaire   +2 more sources

IFNa2 of triploid hybrid of gold fish and allotetraploid is an intracellular antiviral cytokine against SVCV and GCRV

Fish & Shellfish Immunology, 2017
Sterile triploid hybrids (3n = 150) of gold fish (Carassius auratus red var., ♀, 2n = 100) and allotetroploid (♂, 2n = 100) display obviously improved disease resistance and much enhanced growth rate than their parents, which have been cultured widely in China.
Jun, Yan   +6 more
openaire   +2 more sources

In Vitro and In Vivo Antiviral Activity of Histone Deacetylase Inhibitors Against GCRV

Journal of Fish Diseases
ABSTRACT Grass carp haemorrhagic disease (GCHD), a severe viral affliction caused by grass carp reovirus (GCRV), is responsible for significant mortality among grass carp. Characterised by rapid transmission and latent infections, GCHD poses a critical challenge in aquaculture.
Guangyao Hu   +6 more
openaire   +2 more sources

Effects of moroxydine hydrochloride and ribavirin on the cellular growth and immune responses by inhibition of GCRV proliferation

Research in Veterinary Science, 2018
Moroxydine hydrochloride (Mor) and ribavirin (Rib) are known for their multi-antiviral activities against DNA and RNA viruses but little information is available about the pharmacological impact in aquaculture. The present study was undertaken to investigate the response of host cells to antiviral compounds during the anti-GCRV treatment.
Xiao-Bo, Yu   +5 more
openaire   +2 more sources

CiLSM14Aa acts as a cytosolic dsRNA sensor to activate antiviral immunity against GCRV-II

Fish & Shellfish Immunology
The innate immune system relies on pattern recognition receptors (PRRs) to detect viral pathogens and initiate antiviral responses. LSM14A, a conserved RNA-binding protein involved in mRNA metabolism, has recently emerged as a cytosolic nucleic acid sensor in vertebrates. However, its role in teleost immunity remains unclear.
Hui Jiang   +4 more
openaire   +2 more sources

The role of MASP1 in the complement system and expression characteristics in response to GCRV infection in grass carp

Fish & Shellfish Immunology
The grass carp (Ctenopharyngodon idella) constitutes a significant economic resource within the aquaculture sector of our nation, yet it has been chronically afflicted by the Grass Carp Reovirus (GCRV) disease. The complement system, a vital component of fish's innate immunity, plays a crucial role in combating viral infections.
Yuling Wei   +3 more
openaire   +2 more sources

Evaluation of immune efficacy of GCRV vp6 DNA vaccine

Journal of Fishery Sciences of China, 2013
Lin LIU   +9 more
openaire   +1 more source

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