Results 171 to 180 of about 13,346 (214)

GD2-CAR-Engineered Microglia Exhibit Antitumor Effects in Organoids and Animal Models of Retinoblastoma. [PDF]

Invest Ophthalmol Vis Sci
Xu J, Gao Y, Wang J, Lyv M, Zhang Z, Cheng Y, Jin ZB.   +6 more
europepmc   +1 more source

Target antigen-displaying extracellular vesicles boost CAR T cell efficacy in cell and mouse models of neuroblastoma. [PDF]

Sci Transl Med
Giudice AM, Matlaga S, Roth SL, Pascual-Pasto G, Schürch PM, Rouin G, McIntyre B, Grothusen GP, Cresswell-Clay E, Shraim R, Groff D, Zecchino V, Lombardi S, Martinez D, Spruce LA, Brown EM, Fazelinia H, Henrickson SE, Nance J, Reynolds CP, Bosse KR.   +20 more
europepmc   +1 more source

Targeting Sphingolipids in Breast Cancer: From Tumor Biology to Therapeutic Strategies. [PDF]

Oncol Res
Kim MH, Huh B, Park JW, Park WJ.
europepmc   +1 more source

X-optogenetic inhibition of VTA GABA neurons for wireless deep-brain stimulation and suppression of scratching behavior in freely moving mice. [PDF]

Mater Today Bio
Lan B, Liu H, Xu J, Zhang Y, Li D, Gao P, Zhang W, Wang W, Li G, Lu H.   +9 more
europepmc   +1 more source

Exploring the long-term use of ambroxol in Gaucher disease type 2: insights from two pediatric cases. [PDF]

Front Neurol
Aries C, Köhn A, Täuber K, Rudolph C, Böttcher T, Bauer P, Fischer S, Muschol N.   +7 more
europepmc   +1 more source

Myeloid derived suppressor cells in neuroblastoma: mechanisms of immune evasion and therapeutic opportunities. [PDF]

Front Immunol
Choo HS, Yu T, Pham T, Singh N, Joshi S.
europepmc   +1 more source

BACH2 dosage establishes the hierarchy of stemness and fine-tunes antitumor immunity in CAR T cells. [PDF]

Nat Immunol
Hu T, Zhu Z, Luo Y, Wizzard S, Hoar J, Shinde SS, Yihunie K, Yao C, Wu T.   +8 more
europepmc   +1 more source

Expression of Disialoganglioside (GD2) in Neuroblastic Tumors: A Prognostic Value for Patients Treated With Anti-GD2 Immunotherapy

Pediatric and Developmental Pathology, 2017
Neuroblastoma, a malignant neoplasm of the sympathetic nervous system, is one of the most aggressive pediatric cancers. Patients with stage IV high-risk neuroblastoma receive an intensive multimodal therapy ending with an immunotherapy based on a chimeric monoclonal antibody ch14.18.
Tatjana, Terzic, Martine, Cordeau, Sabine, Herblot, Pierre, Teira, Sonia, Cournoyer, Mona, Beaunoyer, Michel, Peuchmaur, Michel, Duval, Herve, Sartelet   +8 more
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Disialoganglioside GD2 as a therapeutic target for human diseases

Expert Opinion on Therapeutic Targets, 2015
Ganglioside GD2 is found in vertebrates and invertebrates, overexpressed among pediatric and adult solid tumors, including neuroblastoma, glioma, retinoblastoma, Ewing's family of tumors, rhabdomyosarcoma, osteosarcoma, leiomyosarcoma, liposarcoma, fibrosarcoma, small cell lung cancer and melanoma.
Maya Suzuki
exaly   +3 more sources