Results 61 to 70 of about 37,648 (242)

Expression levels and diagnostic value of serum GDNF, CEA and CA199 in patients with colorectal carcinoma [PDF]

Journal of Medical Biochemistry
Background: To investigate the expression levels and diagnostic value of glial cell line-derived neurotrophic factor (GDNF), carcinoembryonic antigen (CEA) and carbohydrate antigen199 (CA199) in patients with colorectal carcinoma (CRC).
Jue Wang, Lulu Liu, Yan Zheng, Gu Sai
doaj   +1 more source

TGF-β1 Increases GDNF Production by Upregulating the Expression of GDNF and Furin in Human Granulosa-Lutein Cells

Cells, 2020
Glial cell line-derived neurotrophic factor (GDNF) is expressed at a high level in the human ovary and GDNF signaling is involved in the direct control of follicular activation and oocyte maturation. Transforming growth factor-β1 (TGF-β1) plays
Jingwen Yin, Hsun-Ming Chang, Yuyin Yi, Yuanqing Yao, Peter C.K. Leung   +4 more
doaj   +1 more source

Changing muscle function with sustained glial derived neurotrophic factor treatment of rabbit extraocular muscle. [PDF]

PLoS ONE, 2018
Recent microarray and RNAseq experiments provided evidence that glial derived neurotrophic factor (GDNF) levels were decreased in extraocular muscles from human strabismic subjects compared to age-matched controls.
Krysta R Fitzpatrick, Anja Cucak, Linda K McLoon   +2 more
doaj   +1 more source

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

Concentration of GDNF in sonicated tissues after focused ultrasound-induced BBB disruption post-injection with GDNF (800 µg/kg) through the tail vein.

, 2013
(A) Control group (unsonicated group). (B) MB and GDNF group (GDNF group).
Yun Chen (377354), Chengyu Sun (291981), Hairong Zheng (291979), Li Liu (75607), Feng Wang (44414), Youli Cai (291978), Jie Shi (130059), Fei Yan (128878), Shukun Lu (291982), Yu Shi (117923), Lin Lu (5759), Chao Zou (291980), Xin Liu (43569)   +12 more
core   +1 more source

Exploring the diversity of biological processes regulated by glial cell line-derived neurotrophic factor, a pleiotropic molecule with therapeutic potential

Frontiers in Physiology
Glial cell line–derived neurotrophic factor (GDNF) is a potent trophic factor essential for neuronal survival and function. Encoded by the GDNF gene, its mature protein arises from specific post-translational modifications and is secreted through ...
Cristina Porcari, Cristina Porcari, Stefano Cattaneo, Lucia Crippa, Michele Simonato, Michele Simonato, Barbara Bettegazzi, Barbara Bettegazzi   +7 more
doaj   +1 more source

Extracellular Vesicles‐Based Biological Macromolecule Delivery Systems: Biogenesis, Characterization, and Emerging Clinical Applications

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu, Zeynep Betül Sarı, Muhammed Emin Sarı, Erdi Can Aytar   +3 more
wiley   +1 more source

Development of the urogenital system is regulated via the 3 ' UTR of GDNF [PDF]

, 2019
Mechanisms controlling ureter lenght and the position of the kidney are poorly understood. Glial cellline derived neurotrophic factor (GDNF) induced RET signaling is critical for ureteric bud outgrowth, but the function of endogenous GDNF in further ...
Gui, Y, Kumar, A, Li, Hao, Sipilä, Petra, Ola, Roxana, Li, H, Sipila, P, Kumar, Anmol, Jakobson, Madis, Kuure, S, Andressoo, Jaan-Olle, Gui, Yujuan, Sariola, H, Kuure, Satu, Jakobson, M, Ola, R, Sariola, Hannu, Andressoo, J-O, Yujuan Gui, Roxana Ola, Satu Kuure, Hao Li, Anmol Kumar, Petra Sipilä, Hannu Sariola, Jaan-Olle Andressoo, Madis Jakobson   +26 more
core   +1 more source

The effect of combined training (core stability, resistance and balance) on serum BDNF and GDNF levels in individuals with multiple sclerosis [PDF]

Journal of Exercise & Organ Cross Talk
Multiple sclerosis (MS) is a chronic neurological disease associated with neurodegeneration and impaired neurotrophic support. Neuromuscular training, through integrated activation of the nervous and muscular systems, may positively influence these ...
Ahmad Shahid Razi, Khosro Jalali Dehkordi, Asaad Adnan Aziz, Farzaneh Taghian, Ahmad Chitsaz   +4 more
doaj   +1 more source

Kidney development in the absence of Gdnf and Spry1 requires Fgf10. [PDF]

PLoS Genetics, 2010
GDNF signaling through the Ret receptor tyrosine kinase (RTK) is required for ureteric bud (UB) branching morphogenesis during kidney development in mice and humans.
Odyssé Michos, Cristina Cebrian, Deborah Hyink, Uta Grieshammer, Linda Williams, Vivette D'Agati, Jonathan D Licht, Gail R Martin, Frank Costantini   +8 more
doaj   +1 more source