Results 21 to 30 of about 16,607 (189)
Novel insights into the RTK-dependent metastatic phenotype of KRAS-mutant lung adenocarcinoma
Molecular & Cellular Oncology, 2021 In a recent study, our group identified RAC guanine nucleotide exchange factors (RAC-GEFs) driving motility signaling in KRAS mutant lung adenocarcinoma cells.
Mariana Cooke
doaj +1 more source
Nefrología Latinoamericana, 2023 Objetivo: Determinar los factores clínicos, histopatológicos y sociodemográficos relacionados con el patrón morfológico de glomeruloesclerosis focal y segmentaria (GEFS). Método: Estudio observacional descriptivo de corte transversal.
Isaac D. Navarro-Páez +5 more
doaj +1 more source
Verification of Ensemble Track Forecasts of Tropical Cyclones During 2014
Tropical Cyclone Research and Review, 2015 : The track forecasts of five ensemble prediction systems (JMA-WEPS, CMA-GEFS, ECMWF-EPS, NCEP-GEFS and MSC-CENS, respectively) in 2014 are evaluated in this paper. First, on the assumption of bivariate normal distribution, a probability ellipse based on
Xiping Zhang +3 more
doaj +1 more source
Immature Oocytes in “Apparent Empty Follicle Syndrome”: A Case Report
Case Reports in Medicine, 2010 Empty follicle syndrome (EFS) is a condition in which no oocytes are obtained after an apparently successful ovarian stimulation. Genuine EFS (GEFS) is differentiated from false EFS by an optimal level of human chorionic gonadotropin on the day of oocyte
Teraporn Vutyavanich +2 more
doaj +1 more source
Emerging Roles of Ephexins in Physiology and Disease
Cells, 2019 Dbl (B-cell lymphoma)-related guanine nucleotide exchange factors (GEFs), the largest family of GEFs, are directly responsible for the activation of Rho family GTPases and essential for a number of cellular events such as proliferation, differentiation ...
Kwanhyeong Kim, Sang-Ah Lee, Daeho Park
doaj +1 more source
Targeting Rac and Cdc42 GEFs in Metastatic Cancer
Frontiers in Cell and Developmental Biology, 2020 The Rho family GTPases Rho, Rac, and Cdc42 have emerged as key players in cancer metastasis, due to their essential roles in regulating cell division and actin cytoskeletal rearrangements; and thus, cell growth, migration/invasion, polarity, and adhesion.
Maria del Mar Maldonado +3 more
doaj +1 more source
Angewandte Chemie, EarlyView.Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma +5 more
wiley +2 more sources
Clinical Study and Molecular Genetic Analyses of Malaysian GEFS+ Patients [PDF]
, 2010 Generalized epilepsy with febrile seizure plus (GEFS+) is a familial epilepsy syndrome characterized by phenotypic and genetic heterogeneity. Neuronal voltage gated sodium channel α-1 subunit gene, SCN1A is the most clinically relevant and ...
Salmi Abdul Razak +3 more
core +1 more source
pNARA v1.0 system (GEFS-Aerosols and JEDI)
, 2023 This includes the source code of GEFS-Aerosols and JEDI used to conduct the aerosol reanalysis product for the prototype NOAA Aerosol Reanalysis version 1.0 (pNARA v1.0)
Pagowski, Mariusz +4 more
core +1 more source
Development of the CCPP-based GEFS-aerosols component in the Unified Forecast System for subseasonal prediction (UFS-Chem v1.0) [PDF]
Geoscientific Model DevelopmentThe Global Ensemble Forecast System (GEFS) version 12 has been operational at the National Centers for Environmental Prediction since September 2020, with GEFS-Aerosols serving as its global aerosol forecasting member. In 2023, GEFS-Aerosols was upgraded
L. Zhang +31 more
doaj +1 more source