Results 181 to 190 of about 100,614 (290)

Predictive factors of the treatment outcome in patients with advanced biliary tract cancer receiving gemcitabine plus cisplatin as first-line chemotherapy [PDF]

, 2018
Yuko Suzuki, Motoyasu Kan, Gen Kimura, Kumiko Umemoto, Kazuo Watanabe, Mitsuhito Sasaki, Hideaki Takahashi, Yusuke Hashimoto, Hiroshi Imaoka, Izumi Ohno, Shuichi Mitsunaga, Masafumi Ikeda   +11 more
openalex   +1 more source

Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery

MedComm – Oncology, Volume 5, Issue 1, March 2026.
This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem, Atif Ali, Wajid Ali, Yuying Cheng, Zhibin Yan, Chaoyi Xia, Chenguang Liu, Caiyun Fu, Yiren Hu, Xi Wang   +9 more
wiley   +1 more source

Expanding the payload scope in antibody-drug conjugates by delivery of hydroxy-containing drugs through self-immolative phosphoramidates. [PDF]

Nat Commun
Ochtrop P, Jagtap AP, Felber JG, Vogt S, Herterich S, Mai I, Cyprys P, Schmitt S, Payer S, Kitowski A, Wunder S, Machui P, Brandmeier J, Leonardi N, Poliak E, Hackenberger CPR, Marcq O, Schumacher D, Helma J, Vogl AM, Kasper MA.   +20 more
europepmc   +1 more source

Engineered a Gemcitabine Nano‐Prodrug Targeting Desmoplastic Pancreatic Tumor with Dual Enhancement of Penetration Dynamics [PDF]

Qida Hu, Fu Zhang, Bowen Li, Piaopiao Jin, Junming Huang, Zhuo Yao, Xinyu Zhao, Shiyi Shao, Meng Wang, Ping Yuan, Tingbo Liang   +10 more
openalex   +1 more source

Plasma proteomic profiling and molecular clustering reveal immune‐defined prognostic subtypes in lung adenocarcinoma

International Journal of Cancer, Volume 158, Issue 4, Page 858-865, 15 February 2026.
What's new? Lung adenocarcinoma shows considerable heterogeneity in disease progression and therapeutic response. Here, the authors analyzed tumor samples through proteomic profiling and applied network‐based clustering. They identified two distinct patient groups with different demographic, clinical, and molecular characteristics.
Ujjwal Neogi, Anoop T. Ambikan, Kati Turkowski, Marc A. Schneider, Vanessa M. Beutgen, Johannes Graumann, Hauke Winter, Marek Bartkuhn, Werner Seeger, Soni S. Pullamsetti, Rajkumar Savai   +10 more
wiley   +1 more source

Integrated multi-omics elucidates <i>PRNP</i> knockdown-mediated chemosensitization to gemcitabine in pancreatic ductal adenocarcinoma. [PDF]

Front Immunol
Qi B, Wu Y, Wang N, Duan L, Wei Y, Zhang X, Chen J.   +6 more
europepmc   +1 more source

Potential Targets and Biomarkers of Radionuclide Therapy in Breast Cancer

Cancer Innovation, Volume 5, Issue 1, February 2026.
Potential biomarkers for the development of targeted radionuclide therapy that can be employed in the treatment of breast cancer have been summarised in the review. They include receptor markers of ER, PR and HER2, as well as other markers of Trop2, PD‐1, EGFR, GRPR and PSMA.
Yujing Tan, Cheng Zeng, Jiani Wang, Fei Ma   +3 more
wiley   +1 more source

Gemcitabine + Cisplatin + S-1 Treatment for Advanced Cholangiocarcinoma: Cost-Effective, with Better Progression-Free Survival Versus Standard Treatment with Gemcitabine + Cisplatin + Durvalumab. [PDF]

Cancers (Basel)
Morita Y, Sugimoto R, Kurokawa M, Tanaka Y, Senju T, Ichimaru T, Lee L, Niina Y, Hisano T, Furukawa M, Sugimachi K, Tanaka M.   +11 more
europepmc   +1 more source

Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Emerging studies indicate that microbes are present in tumor cells and immune cells. Intratumoral microbiota (ITM) constitute an important component of the tumor immune microenvironment (TIME) and have an important impact on tumor progression and treatment. Objective Through the general elaboration of ITM represented by bacteria and
Fengxue Li, Lili Qiao, Xinquan Liang, Yingying Zhang, Ning Liang, Jian Xie, Guodong Deng, Yuying Hao, Pingping Hu, Xue Wu, Fangjie Ding, Can Feng, Yiming Mu, Jiandong Zhang   +13 more
wiley   +1 more source

A Case of Pathological Complete Response after "Conversion Surgery" for Initially Unresectable Locally Advanced Intrahepatic Cholangiocarcinoma. [PDF]

Surg Case Rep
Shirakawa Y, Yoh T, Ito T, Ogiso S, Ishii T, Fujimoto M, Haga H, Hatano E.   +7 more
europepmc   +1 more source