Results 191 to 200 of about 7,371,567 (249)
Gene amplification in cultured cells.
Journal of Biological Chemistry, 1988 openaire +3 more sources
Alternative Model for Gene Amplification [PDF]
Nature New Biology, 1971 The number of nucleoli increases shortly after the conversion of germ cells into oogonia or spermatogonia in Xenopus laevis. This event demands a modification of the theory of gene amplification. A new explanation is proposed which involves non-chromosomal genes restricted to the germ-line.
J. Morray +2 more
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Regulation and mechanisms of gene amplification
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 1995Amplification in rodent cells usually involves bridge-breakage-fusion (bbf) cycles initiated either by endto-end fusion of sister chromatids, or by chromosome breakage. In contrast, in human cells, resistance to the antimetabolite A-(phosphonacetyl)-L-aspartate (PALA) can be mediated by several different mechanisms that lead to ...
Yutaka Deguchi +8 more
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Fluorometric Detection of MicroRNA Using Isothermal Gene Amplification and Graphene Oxide.
Analytical Chemistry, 2016We have developed a facile fluorometric system for the detection of microRNA (miRNA), using rolling circle amplification (RCA), graphene oxide (GO), and fluorescently labeled peptide nucleic acid (F-PNA).
Chaesun Hong +4 more
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EPSPS gene amplification in glyphosate-resistant Bromus diandrus.
Pest Management Science, 2016BACKGROUND Glyphosate is the most widely used herbicide in the world and has been intensively used to control B. diandrus, a problematic weed of crops and pastures in southern Australia.
Jenna M. Malone +4 more
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Trends in Genetics, 2006
Gene amplification is a copy number increase of a restricted region of a chromosome arm. It is prevalent in some tumors and is associated with overexpression of the amplified gene(s). Amplified DNA can be organized as extrachromosomal elements, as repeated units at a single locus or scattered throughout the genome.
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Gene amplification is a copy number increase of a restricted region of a chromosome arm. It is prevalent in some tumors and is associated with overexpression of the amplified gene(s). Amplified DNA can be organized as extrachromosomal elements, as repeated units at a single locus or scattered throughout the genome.
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GENE AMPLIFICATION IN LEISHMANIA
Annual Review of Microbiology, 1991INTRODUCTION . . . . . . . . . . . . .. . .... . . .... . . . . . . . . . . . . . . . . . . . . . .. . ... . . . .. . . . .. . . .. . . .. .. . .. . . . . . . . . . . 417 A Leishmania Primer 4 1 8 The Leishmania Genome and Circular DNAs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Induction of Gene Amplification by Arsenic
Science, 1988Arsenic is a well-established carcinogen in humans, but there is little evidence for its carcinogenicity in animals and it is inactive as an initiator or tumor promoter in two-stage models of carcinogenicity in mice. Two arsenic salts (sodium arsenite and sodium arsenate) induced a high frequency of methotrexate-resistant 3T6 cells, which were shown to
Patricia W. Lamb +4 more
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Science, 1987
The HER-2/neu oncogene is a member of the erbB-like oncogene family, and is related to, but distinct from, the epidermal growth factor receptor. This gene has been shown to be amplified in human breast cancer cell lines. In the current study, alterations
D. Slamon +5 more
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The HER-2/neu oncogene is a member of the erbB-like oncogene family, and is related to, but distinct from, the epidermal growth factor receptor. This gene has been shown to be amplified in human breast cancer cell lines. In the current study, alterations
D. Slamon +5 more
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Gene Amplification and Insecticide Resistance
Annual Review of Entomology, 1991Recapitulation des travaux portant sur le mecanisme de resistance des insectes face aux substances toxiques, base sur l'amplification des genes de resistance.
Alan L. Devonshire, Linda M. Field
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