Results 191 to 200 of about 8,013,600 (393)

Deep learning to automatically evaluate HER2 gene amplification status from fluorescence in situ hybridization images. [PDF]

Sci Rep, 2023
Xue T, Chang H, Ren M, Wang H, Yang Y, Wang B, Lv L, Tang L, Fu C, Fang Q, He C, Zhu X, Zhou X, Bai Q.   +13 more
europepmc   +1 more source

Antifolate-resistant Chinese hamster cells. Evidence for dihydrofolate reductase gene amplification among independently derived sublines overproducing different dihydrofolate reductases.

, 1980
Peter W. Melera, John A. Lewis, June L. Biedler, Catherine Hession   +3 more
openalex   +1 more source

Human tumor cell lines with EGF receptor gene amplification in the absence of aberrant sized mRNAs [PDF]

, 1985
C. Richter King, Matthias H. Kraus, Lewis T. Williams, Glenn Merlino, Ira Pastan, Stuart A. Aaronson   +5 more
openalex   +1 more source

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

SARS-CoV-2 Nucleocapsid Protein Mutations Found in Switzerland Disrupt N-Gene Amplification in Commonly Used Multiplex RT-PCR Assay. [PDF]

Pathogens, 2023
Hilti D, Wehrli F, Roditscheff A, Risch M, Risch L, Egli A, Bodmer T, Wohlwend N.   +7 more
europepmc   +1 more source

Amplification and modification of dihydrofolate reductase in Escherichia coli. Nucleotide sequence of fol genes from mutationally altered plasmids.

, 1982
Andrew R. Smith, Julian I. Rood, Phillip I. Bird, Margaret K. Sneddon, Joseph M. Calvo, John F. Morrison   +5 more
openalex   +1 more source

Overcoming interference to retroviral superinfection results in amplified expression and transmission of cloned genes. [PDF]

, 1988
Richard K. Bestwick, Susan L. Kozak, David Kabat   +2 more
openalex   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

MET gene amplification is a mechanism of resistance to entrectinib in ROS1+ NSCLC. [PDF]

Thorac Cancer, 2022
Tyler LC, Le AT, Chen N, Nijmeh H, Bao L, Wilson TR, Chen D, Simmons B, Turner KM, Perusse D, Kasibhatla S, Christiansen J, Dudek AZ, Doebele RC.   +13 more
europepmc   +1 more source

The PVT gene frequently amplifies with MYC in tumor cells. [PDF]

, 1989
Emma Shtivelman, J. Michael Bishop
openalex   +1 more source