Results 21 to 30 of about 7,510,778 (382)
Nucleic Acids Res., 2022 DAVID is a popular bioinformatics resource system including a web server and web service for functional annotation and enrichment analyses of gene lists. It consists of a comprehensive knowledgebase and a set of functional analysis tools. Here, we report
Brad T. Sherman +7 more
semanticscholar +1 more source
Capturing heart valve development with Gene Ontology
Frontiers in Genetics, 2023 Introduction: The normal development of all heart valves requires highly coordinated signaling pathways and downstream mediators. While genomic variants can be responsible for congenital valve disease, environmental factors can also play a role. Later in
Saadullah H. Ahmed +4 more
doaj +1 more source
GOing Forward With the Cardiac Conduction System Using Gene Ontology
Frontiers in Genetics, 2022 The cardiac conduction system (CCS) comprises critical components responsible for the initiation, propagation, and coordination of the action potential. Aberrant CCS development can cause conduction abnormalities, including sick sinus syndrome, accessory
Kan Yan Chloe Li +3 more
doaj +1 more source
Insights into Online microRNA Bioinformatics Tools
Non-Coding RNA, 2023 MicroRNAs (miRNAs) are members of the small non-coding RNA family regulating gene expression at the post-transcriptional level. MiRNAs have been found to have critical roles in various biological and pathological processes.
Diana Luna Buitrago +2 more
doaj +1 more source
Annotation of plasmid genes [PDF]
Plasmid, 2017 Good annotation of plasmid genomes is essential to maximise the value of the rapidly increasing volume of plasmid sequences. This short review highlights some of the current issues and suggests some ways forward. Where a well-studied related plasmid system exists we recommend that new annotation adheres to the convention already established for that ...
Thomas, Christopher M +5 more
openaire +2 more sources
AMIGene: Annotation of MIcrobial Genes [PDF]
Nucleic Acids Research, 2003 AMIGene (Annotation of MIcrobial Genes) is an application for automatically identifying the most likely coding sequences (CDSs) in a large contig or a complete bacterial genome sequence. The first step in AMIGene is dedicated to the construction of Markov models that fit the input genomic data (i.e.
Nuel, Gregory +4 more
openaire +3 more sources
bioRxiv, 2021 Even though automated functional annotation of genes represents a fundamental step in most genomic and metagenomic workflows, it remains challenging at large scales.
C. Cantalapiedra +4 more
semanticscholar +1 more source
Logical Gene Ontology Annotations (GOAL): exploring gene ontology annotations with OWL [PDF]
Journal of Biomedical Semantics, 2012 Ontologies such as the Gene Ontology (GO) and their use in annotations make cross species comparisons of genes possible, along with a wide range of other analytical activities. The bio-ontologies community, in particular the Open Biomedical Ontologies (OBO) community, have provided many other ontologies and an increasingly large volume of annotations ...
Jupp, Simon +2 more
openaire +4 more sources
BMC Genomics, 2021 Background Functional genome annotation is the process of labelling functional genomic regions with descriptive information. Manual curation can produce higher quality genome annotations than fully automated methods.
Matthew R. Lueder +6 more
doaj +1 more source
PINOT: an intuitive resource for integrating protein-protein interactions
Cell Communication and Signaling, 2020 Background The past decade has seen the rise of omics data for the understanding of biological systems in health and disease. This wealth of information includes protein-protein interaction (PPI) data derived from both low- and high-throughput assays ...
James E. Tomkins +7 more
doaj +1 more source