Results 21 to 30 of about 208,264 (275)
Logical Gene Ontology Annotations (GOAL): exploring gene ontology annotations with OWL [PDF]
Journal of Biomedical Semantics, 2012 Ontologies such as the Gene Ontology (GO) and their use in annotations make cross species comparisons of genes possible, along with a wide range of other analytical activities. The bio-ontologies community, in particular the Open Biomedical Ontologies (OBO) community, have provided many other ontologies and an increasingly large volume of annotations ...
Jupp, Simon +2 more
openaire +5 more sources
A Gene Wiki for Community Annotation of Gene Function
PLoS Biology, 2008 This manuscript describes the creation of comprehensive gene wiki, seeded with data from public domain sources, which will enable and encourage community annotation of gene function.
Jon W. Huss +7 more
openalex +6 more sources
Using genomic annotations increases statistical power to detect eGenes. [PDF]
, 2016 MotivationExpression quantitative trait loci (eQTLs) are genetic variants that affect gene expression. In eQTL studies, one important task is to find eGenes or genes whose expressions are associated with at least one eQTL. The standard statistical method
Duong, Dat +6 more
core +1 more source
Functional genome Annotation in Bacterial infections: A Review [PDF]
Al Ameen Journal of Medical Sciences, 2021 Functional annotation provides the information of gene about its biological identity and various types of molecular function and biological role like sub-cellular location and its expression.
Sharique Ahmad +3 more
doaj
A large-scale proteogenomics study of apicomplexan pathogens-Toxoplasma gondii and Neospora caninum [PDF]
, 2015 Proteomics data can supplement genome annotation efforts, for example being used to confirm gene models or correct gene annotation errors. Here, we present a large‐scale proteogenomics study of two important apicomplexan pathogens: Toxoplasma gondii and ...
Bernal, A +11 more
core +1 more source
Missing genes in the annotation of prokaryotic genomes [PDF]
BMC Bioinformatics, 2010 Protein-coding gene detection in prokaryotic genomes is considered a much simpler problem than in intron-containing eukaryotic genomes. However there have been reports that prokaryotic gene finder programs have problems with small genes (either over-predicting or under-predicting).
Jeremy Archuleta +5 more
openaire +4 more sources
A curated catalog of canine and equine keratin genes. [PDF]
PLoS ONE, 2017 Keratins represent a large protein family with essential structural and functional roles in epithelial cells of skin, hair follicles, and other organs. During evolution the genes encoding keratins have undergone multiple rounds of duplication and humans ...
Pierre Balmer +9 more
doaj +1 more source
Student biocuration projects as a learning environment [version 2; peer review: 2 approved]
F1000Research, 2022 Background: Bioinformatics is becoming an essential tool for the majority of biological and biomedical researchers. Although bioinformatics data is exploited by academic and industrial researchers, limited focus is on teaching this area to undergraduates,
Ruth C. Lovering +2 more
doaj
BMC Research Notes, 2012 Background Bioinformatics and high-throughput technologies such as microarray studies allow the measure of the expression levels of large numbers of genes simultaneously, thus helping us to understand the molecular mechanisms of various biological ...
Michalopoulos Ioannis +6 more
doaj +1 more source
Impact of gene annotation choice on the quantification of RNA-seq data
BMC Bioinformatics, 2022 Background RNA sequencing is currently the method of choice for genome-wide profiling of gene expression. A popular approach to quantify expression levels of genes from RNA-seq data is to map reads to a reference genome and then count mapped reads to ...
David Chisanga, Yang Liao, Wei Shi
doaj +1 more source