Results 11 to 20 of about 10,955,304 (331)

FusionGDB: fusion gene annotation DataBase. [PDF]

Nucleic Acids Res, 2019
Gene fusion is one of the hallmarks of cancer genome via chromosomal rearrangement initiated by DNA double-strand breakage. To date, many fusion genes (FGs) have been established as important biomarkers and therapeutic targets in multiple cancer types ...
Kim P, Zhou X.
europepmc   +5 more sources

A gene wiki for community annotation of gene function. [PDF]

PLoS Biology, 2008
This manuscript describes the creation of comprehensive gene wiki, seeded with data from public domain sources, which will enable and encourage community annotation of gene function.
Jon W Huss, Camilo Orozco, James Goodale, Chunlei Wu, Serge Batalov, Tim J Vickers, Faramarz Valafar, Andrew I Su   +7 more
doaj   +6 more sources

The Ensembl gene annotation system [PDF]

Database, 2016
The Ensembl gene annotation system has been used to annotate over 70 different vertebrate species across a wide range of genome projects. Furthermore, it generates the automatic alignment-based annotation for the human and mouse GENCODE gene sets.
B. Aken, S. Ayling, D. Barrell, Laura Clarke, V. Curwen, Susan Fairley, Julio Fernandez Banet, Konstantinos Billis, Carlos García Girón, Thibaut Hourlier, K. Howe, A. Kähäri, F. Kokocinski, Fergal J. Martin, Daniel N. Murphy, Rishi Nag, Magali Ruffier, M. Schuster, Y. Tang, J. Vogel, S. White, A. Zadissa, P. Flicek, S. Searle   +23 more
semanticscholar   +5 more sources

Gene Annotation Easy Viewer (GAEV): Integrating KEGG’s Gene Function Annotations and Associated Molecular Pathways [version 3; peer review: 1 approved, 2 approved with reservations]

F1000Research, 2019
We developed a Gene Annotation Easy Viewer (GAEV) that integrates the gene annotation data from the KEGG (Kyoto Encyclopedia of Genes and Genomes) Automatic Annotation Server.
Trung Huynh, Sen Xu
doaj   +2 more sources

The state of play in higher eukaryote gene annotation

Nature Reviews Genetics, 2016
A genome sequence is worthless if it cannot be deciphered; therefore, efforts to describe — or 'annotate' — genes began as soon as DNA sequences became available.
Jennifer Harrow, Jonathan M Mudge
exaly   +2 more sources

Hayai-Annotation: A functional gene prediction tool that integrates orthologs and gene ontology for network analysis in plant species

Computational and Structural Biotechnology Journal
Hayai-Annotation, an annotation tool powered by the R-shinydashboard browser interface, implements a workflow that integrates sequence alignment using DIAMOND against UniProtKB Plants and ortholog inference using OrthoLoger. We here propose a pipeline to
Andrea Ghelfi, Sachiko Isobe
doaj   +3 more sources

Consistent annotation of gene expression arrays [PDF]

BMC Genomics, 2010
Background Gene expression arrays are valuable and widely used tools for biomedical research. Today's commercial arrays attempt to measure the expression level of all of the genes in the genome.
Proctor Glenn, Johnson Nathan, Ballester Benoît, Flicek Paul   +3 more
doaj   +4 more sources

Gene characterization index: assessing the depth of gene annotation.

PLoS ONE, 2008
BackgroundWe introduce the Gene Characterization Index, a bioinformatics method for scoring the extent to which a protein-encoding gene is functionally described. Inherently a reflection of human perception, the Gene Characterization Index is applied for
Danielle Kemmer, Raf M Podowski, Dimas Yusuf, Jochen Brumm, Warren Cheung, Claes Wahlestedt, Boris Lenhard, Wyeth W Wasserman   +7 more
doaj   +3 more sources

Long-read transcriptomics of a diverse human cohort reveals ancestry bias in gene annotation [PDF]

Nature Communications
Marta Melé, Winona Oliveros, Roderic Guigó i Serra   +2 more
exaly   +2 more sources

Incorporating Gene Annotation into Genomic Prediction of Complex Phenotypes

Genetics, 2017
Zhe Zhang, Ning Gao, Xiaolong Yuan
exaly   +2 more sources