Results 41 to 50 of about 566,833 (345)

EAnnot: A genome annotation tool using experimental evidence [PDF]

open access: yes, 2004
The sequence of any genome becomes most useful for biological experimentation when a complete and accurate gene set is available. Gene prediction programs offer an efficient way to generate an automated gene set.
Berkowicz, Nicolas   +8 more
core   +3 more sources

CANT-HYD: A Curated Database of Phylogeny-Derived Hidden Markov Models for Annotation of Marker Genes Involved in Hydrocarbon Degradation

open access: yesFrontiers in Microbiology, 2022
Many pathways for hydrocarbon degradation have been discovered, yet there are no dedicated tools to identify and predict the hydrocarbon degradation potential of microbial genomes and metagenomes.
Varada Khot   +11 more
doaj   +1 more source

Discovery of a Novel Intron in US10/US11/US12 of HSV-1 Strain 17

open access: yesViruses, 2023
Herpes Simplex Virus type 1 (HSV-1) infects humans and causes a variety of clinical manifestations. Many HSV-1 genomes have been sequenced with high-throughput sequencing technologies and the annotation of these genome sequences heavily relies on the ...
Weizhong Chang   +4 more
doaj   +1 more source

EuCAP, a Eukaryotic Community Annotation Package, and its application to the rice genome

open access: yesBMC Genomics, 2007
Background Despite the improvements of tools for automated annotation of genome sequences, manual curation at the structural and functional level can provide an increased level of refinement to genome annotation.
Hamilton John P   +4 more
doaj   +1 more source

Non‐homology‐based prediction of gene functions in maize (Zea mays ssp. mays)

open access: yesThe Plant Genome, 2020
Advances in genome sequencing and annotation have eased the difficulty of identifying new gene sequences. Predicting the functions of these newly identified genes remains challenging.
Xiuru Dai   +6 more
doaj   +1 more source

On gene ontology and function annotation [PDF]

open access: yesBioinformation, 2006
The effort of function annotation does not merely involve associating a gene with some structured vocabulary that describes action. Rather the details of the actions, the components of the actions, the larger context of the actions are important issues that are of direct relevance, because they help understand the biological system to which the gene ...
openaire   +3 more sources

Gene Ontology Meta Annotator for Plants (GOMAP) [PDF]

open access: yesPlant Methods, 2019
AbstractAnnotating gene structures and functions to genome assemblies is necessary to make assembly resources useful for biological inference. Gene Ontology (GO) term assignment is the most used functional annotation system, and new methods for GO assignment have improved the quality of GO-based function predictions.
Wimalanathan, Kokulapalan   +1 more
openaire   +6 more sources

A novel Modulator of Ring Stage Translation (MRST) gene alters artemisinin sensitivity in Plasmodium falciparum

open access: yesmSphere, 2023
The implementation of artemisinin (ART) combination therapies (ACTs) has greatly decreased deaths caused by Plasmodium falciparum malaria, but increasing ACT resistance in Southeast Asia and Africa could reverse this progress. Parasite population genetic
Caroline Simmons   +11 more
doaj   +1 more source

GoGene: gene annotation in the fast lane [PDF]

open access: yesNucleic Acids Research, 2009
High-throughput screens such as microarrays and RNAi screens produce huge amounts of data. They typically result in hundreds of genes, which are often further explored and clustered via enriched GeneOntology terms. The strength of such analyses is that they build on high-quality manual annotations provided with the GeneOntology.
Michael Schroeder   +4 more
openaire   +3 more sources

Annotation extension through protein family annotation coherence metrics

open access: yesFrontiers in Genetics, 2013
Protein functional annotation consists in associating proteins with textual descriptors elucidating their biological roles. The bulk of annotation is done via automated procedures that ultimately rely on annotation transfer.
Hugo Paulo Bastos   +2 more
doaj   +1 more source

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