A novel cassette method for probe evaluation in the designed biochips [PDF]
PLoS ONE, 2014 A critical step in biochip design is the selection of probes with identical hybridisation characteristics. In this article we describe a novel method for evaluating DNA hybridisation probes, allowing the fine-tuning of biochips, that uses cassettes with ...
Al-humam, Abdulmohsen A. +7 more
core +25 more sources
Biochar and Manure Applications Differentially Altered the Class 1 Integrons, Antimicrobial Resistance, and Gene Cassettes Diversity in Paddy Soils. [PDF]
Front Microbiol, 2022 Integrons are genetic components that are critically involved in bacterial evolution and antimicrobial resistance by assisting in the propagation and expression of gene cassettes.
Ali N +7 more
europepmc +2 more sources
Horizontal transfer and evolution of wall teichoic acid gene cassettes in Bacillus subtilis. [PDF]
F1000Res, 2021 Background: Wall teichoic acid (WTA) genes are essential for production of cell walls in gram-positive bacteria and necessary for survival and variability in the cassette has led to recent antibiotic resistance acquisition in pathogenic bacteria ...
Sutton G +6 more
europepmc +2 more sources
The function of integron-associated gene cassettes in Vibrio species: The tip of the iceberg [PDF]
Frontiers in Microbiology, 2013 The integron is a genetic element that incorporates mobile genes termed gene cassettes into a reserved genetic site via site-specific recombination. It is best known for its role in antibiotic resistance with one type of integron, the class 1 integron, a
Labbate, M, Rapa, RA
core +3 more sources
Deletion of Integron-Associated Gene Cassettes Impact on the Surface Properties of Vibrio rotiferianus DAT722 [PDF]
PLoS ONE, 2013 Background: The integron is a genetic recombination system that catalyses the acquisition of genes on mobilisable elements called gene cassettes. In Vibrio species, multiple acquired gene cassettes form a cassette array that can comprise 1-3% of the ...
Djordjevic, SP +4 more
core +3 more sources
Trade-off between canonical and unusual recombination sites promotes diversity and stability of gene cassette arrays of mobile integrons. [PDF]
Sci RepMobile integrons are the most efficient mechanism of Gram-negative bacteria to resist antimicrobial changing pressures in the nosocomial niche. Integron’s integrases mediate site-specific recombination of distinct DNA structures such as attI, attC and ...
Gonzales Machuca A +5 more
europepmc +2 more sources
Highly efficient expression of DNA-peptide conjugates in growth-arrested cells. [PDF]
Nat CommunEfficient nuclear delivery of DNA remains a major challenge in non-viral gene therapy. While nuclear localization signal (NLS) peptides have been explored for enhancing nuclear translocation of DNA, their efficacy has been limited by DNA-peptide ...
Mohamedshah ZY +4 more
europepmc +2 more sources
Ecotoxicology and Environmental Safety, 2022 Rapid spread of antibiotic resistance genes (ARGs) in pathogens is threatening human health. Integrons allow bacteria to integrate and express foreign genes, facilitating horizontal transfer of ARGs in environments.
Cai-Xia Zhao +4 more
doaj +1 more source
Frontiers in Environmental Science, 2022 Antimicrobial resistance (AMR) is a serious public health concern. Many countries have implemented AMR surveillance programs for humans and animals, but a scheme for monitoring AMR in the environment has not yet been established. Class 1 integrons, which
Ikuro Kasuga +4 more
doaj +1 more source
Plants, 2022 Transgenic technology can transfer favorable traits regardless of reproductive isolation and is an important method in plant synthetic biology and genetic improvement.
Guannan Qin +8 more
doaj +1 more source