Results 91 to 100 of about 95,204 (199)

Identification and characterization of class 1 integrons among atypical enteropathogenic Escherichia coli isolated from children under 5 years of age

Iranian Journal of Microbiology, 2014
Background and Objectives: The therapeutic options for diseases caused by Escherichia coli are limited. In this study we investigated the presence of virulence factors among Enteropathogenic Escherichia coli (EPEC) strains and their antibiotic resistance
Farzad Shahcheraghi, Fatemeh Rahmati Ghezelgeh, Saman Nobari, Elham Torabi, Seyed-Fazlollah Mousavi, Mohammad Mehdi Aslani, Fereshteh Shahcheraghi   +6 more
doaj  

Methods for the targeted sequencing and analysis of integrons and their gene cassettes from complex microbial communities. [PDF]

Microb Genom, 2022
Ghaly TM, Penesyan A, Pritchard A, Qi Q, Rajabal V, Tetu SG, Gillings MR.   +6 more
europepmc   +1 more source

Integrons in the Age of Antibiotic Resistance: Evolution, Mechanisms, and Environmental Implications: A Review

Microorganisms
Integrons, which are genetic components commonly found in bacteria, possess the remarkable capacity to capture gene cassettes, incorporate them into their structure, and thereby contribute to an increase in genomic complexity and phenotypic diversity ...
Niyaz Ali, Izhar Ali, Ahmad Ud Din, Kashif Akhtar, Bing He, Ronghui Wen   +5 more
doaj   +1 more source

Introduction of Modified BglBrick System in Lactococcus lactis for Straightforward Assembly of Multiple Gene Cassettes. [PDF]

Front Bioeng Biotechnol, 2021
Plavec TV, Ključevšek T, Berlec A.
europepmc   +1 more source

Robust and stable transcriptional repression in Giardia using CRISPRi. [PDF]

, 2019
Giardia lamblia is a binucleate protistan parasite causing significant diarrheal disease worldwide. An inability to target Cas9 to both nuclei, combined with the lack of nonhomologous end joining and markers for positive selection, has stalled the ...
Booker, J, Dawson, Scott C, Hagen, KD, Jones, K, McInally, SG, Nguyen, K, Nosala, C, Williams, J   +7 more
core   +1 more source

Genetic Determinants of Antibacterial Resistance Among Nosocomial Escherichia coli Klebsiella spp., and Enterobacter spp. Isolates Collected in Russia within 2003-2007

Антибиотики и Химиотерапия, 2020
Nosocomial bacterial Isolates collected within 2003-2004 (n=411) and 2005-2007 (n=422) were highly resistant to cephalosporins III-IV and antibacterials of other groups (aminoglycosides, fluoroquinolons, chloramphenicol, and co-trimoxazole).
S. D. Pryamchuk, N. K. Fursova, I. V. Abaev, YU. N. Kovalev, N. A. Shishkova, E. I. Pecherskikh, O. V. Korobova, E. I. Astashkin, D. M. Pachkunov, A. N. Kruglov, D. V. Ivanov, S. V. Sidorenko, E. A. Svetoch, I. A. Dyatlov   +13 more
doaj  

Generation of a multipurpose Prdm16 mouse allele by targeted gene trapping

Disease Models & Mechanisms, 2017
Gene trap mutagenesis is a powerful tool to create loss-of-function mutations in mice and other model organisms. Modifications of traditional gene trap cassettes, including addition of conditional features in the form of Flip-excision (FlEx) arrays to ...
Alexander Strassman, Frank Schnütgen, Qi Dai, Jennifer C. Jones, Angela C. Gomez, Lenore Pitstick, Nathan E. Holton, Russell Moskal, Erin R. Leslie, Harald von Melchner, David R. Beier, Bryan C. Bjork   +11 more
doaj   +1 more source

Construction of attenuated HIV-1 accessory gene immunization cassettes

Vaccine, 1998
Delivery of genetic expression cassettes into animals can effectively induce both humoral and cellular immunity to the expressed gene product. Previously, we used this strategy to immunize against HIV-1 structural and enzymatic proteins in mice, non-human primates and in humans.
V, Ayyavoo, T, Nagashunmugam, M T, Phung, C, Buckner, S, Kudckodkar, P, Le, P J, Reddy, L, Santiago, M, Patel, L, Tea, D B, Weiner   +10 more
openaire   +2 more sources

Antimicrobial Resistance and Molecular Characterization of Gene Cassettes from Class 1 Integrons in Escherichia coli Strains. [PDF]

Microb Drug Resist, 2022
Li W, Ma J, Sun X, Liu M, Wang H.
europepmc   +1 more source

Cassette deletion in multiple shRNA lentiviral vectors for HIV-1 and its impact on treatment success

Virology Journal, 2009
Background Multiple short hairpin RNA (shRNA) gene therapy strategies are currently being investigated for treating viral diseases such as HIV-1. It is important to use several different shRNAs to prevent the emergence of treatment-resistant strains ...
Shen Sylvie W, Elliott Fiona A, Boyd Maureen P, Millington Michelle L, Arndt Allison J, Jaramillo Angel B, Tran Anna, Yu Yi-Hsin, Mcintyre Glen J, Murray John M, Applegate Tanya L   +10 more
doaj   +1 more source