Kaohsiung Journal of Medical Sciences, 2007 This study characterized class 1 integrons in Escherichia coli in Taiwan. The stability and changes in gene cassettes inserted into integrons were also evaluated. The study included 436 clinical strains of E. coli isolated in 2002. Class 1 integrons were
Lin-Li Chang +2 more
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Integron and its role in antimicrobial resistance: A literature review on some bacterial pathogens [PDF]
Iranian Journal of Basic Medical Sciences, 2021 In recent years, different acquired resistance mechanisms, including transposons, bacteriophages, plasmids, and integrons have been identified as involved in the spread of resistance genes in bacteria.
Parisa Sabbagh +3 more
doaj +1 more source
Sequential and counter-selectable cassettes for fission yeast [PDF]
, 2016 BACKGROUND: Fission yeast is one of the most commonly used model organisms for studying genetics. For selection of desirable genotypes, antibiotic resistance cassettes are widely integrated into the genome near genes of interest.
Amelina, H +5 more
core +1 more source
Extensions of MADM (mosaic analysis with double markers) in mice. [PDF]
PLoS ONE, 2012 Mosaic Analysis with Double Markers (MADM) is a method for generating genetically mosaic mice, in which sibling mutant and wild-type cells are labeled with different fluorescent markers. It is a powerful tool that enables analysis of gene function at the
Bosiljka Tasic +8 more
doaj +1 more source
Strain prioritization and genome mining for enediyne natural products [PDF]
, 2016 The enediyne family of natural products has had a profound impact on modern chemistry, biology, and medicine, and yet only 11 enediynes have been structurally characterized to date.
Ben Shen +18 more
core +2 more sources
Combinatorial Screening for Transgenic Yeasts with High Cellulase Activities in Combination with a Tunable Expression System. [PDF]
PLoS ONE, 2015 Combinatorial screening used together with a broad library of gene expression cassettes is expected to produce a powerful tool for the optimization of the simultaneous expression of multiple enzymes.
Yoichiro Ito +4 more
doaj +1 more source
Correctly Identifying the Streptothricin Resistance Gene Cassette [PDF]
Journal of Clinical Microbiology, 2005 If analysis of the gene cassettes located in class 1 or class 2 integrons found in surveys of antibiotic resistance genes is to be useful in tracking the prevalence and movement of resistance genes, the cassettes must be accurately identified.
Sally R, Partridge, Ruth M, Hall
openaire +2 more sources
Recovery and evolutionary analysis of complete integron gene cassette arrays from
BMC Evolutionary Biology, 2006 Background Integrons are genetic elements capable of the acquisition, rearrangement and expression of genes contained in gene cassettes. Gene cassettes generally consist of a promoterless gene associated with a recombination site known as a 59-base ...
Gillings Michael R +7 more
doaj +1 more source
Societal Costs of Late Blight in Potato and Prospects of Durable Resistance Through Cisgenic Modification [PDF]
, 2008 In the European Union almost 6 Mha of potatoes are grown representing a value of close to ¿6,000,000,000. Late blight caused by Phytophthora infestans causes annual losses (costs of control and damage) estimated at more than ¿1,000,000,000.
Boonekamp, P.M. +7 more
core +2 more sources
Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivo. [PDF]
, 2014 Spores of some species of the strictly anaerobic bacteria Clostridium naturally target and partially lyse the hypoxic cores of tumors, which tend to be refractory to conventional therapies. The anti-tumor effect can be augmented by engineering strains to
Dubois, L +10 more
core +4 more sources