Results 61 to 70 of about 95,204 (199)
BMC Infectious Diseases, 2021 Background Productions of metallo-β-lactamases enzymes are the most common mechanism of antibiotic resistance to all beta-lactam classes (except monobactams) in Acinetobacter baumannii.
Mahnaz Nikibakhsh +4 more
doaj +1 more source
Large-Scale Gene Disruption Using the UAU1 Cassette [PDF]
, 2009 Candida albicans is a major fungal systemic pathogen in humans. Genetic manipulation of C. albicans is unwieldy. We report here a strategy that is useful and successful for large-scale genetic manipulation of C. albicans genes of interest: use of the UAU1 cassette on a Tn7 transposon. Streamlined yet admittedly flawed disruption techniques, such as the
Clarissa J, Nobile, Aaron P, Mitchell
openaire +2 more sources
Characterization of the novel In1059 harbouring VIM gene cassette [PDF]
Antimicrobial Resistance & Infection Control, 2017 VIM-type enzyme encodes the most widely acquired metallo-β-lactamases in Gram- negative bacteria. To obtain current epidemiological data for integrons from enterobacteriae in hospital, the study characterizes the genetic structure in In1059 by comparison with In846 integrons harbouring VIM gene and other class 1 integrons including In37, In62, In843 ...
Dongguo Wang +6 more
openaire +3 more sources
Broad-spectrum β-lactamases among Enterobacteriaceae of animal origin: molecular aspects, mobility and impact on public health [PDF]
, 2010 Broad-spectrum β-lactamase genes (coding for extended-spectrum β-lactamases (ESBLs) and AmpC β-lactamases) have been frequently demonstrated in the microbiota of food-producing animals. This may pose a human health hazard since these genes may be present
Butaye, Patrick +7 more
core +1 more source
Plants, People, PlanetSocietal Impact Statement Plants and bacteria interact in complex ways that are crucial to the health and productivity of native vegetation and croplands. While the range of characterised plant‐beneficial bacterial traits continues to grow, key questions
Vaheesan Rajabal +7 more
doaj +1 more source
New Microbes and New Infections, 2015 A total of 189 Acinetobacter baumannii isolates were collected in 2011 from a teaching hospital in Chongqing, China. Susceptibility data showed strains carrying integrons were significantly more resistant to all tested antibiotics that strains lacking ...
C. Huang +6 more
doaj +1 more source
Multigenic lentiviral vectors for combined and tissue-specific expression of miRNA- and protein-based antiangiogenic factors. [PDF]
, 2015 Lentivirus-based gene delivery vectors carrying multiple gene cassettes are powerful tools in gene transfer studies and gene therapy, allowing coexpression of multiple therapeutic factors and, if desired, fluorescent reporters.
Aagaard, L. +8 more
core +3 more sources
Gene Cassette PCR: Sequence-Independent Recovery of Entire Genes from Environmental DNA [PDF]
Applied and Environmental Microbiology, 2001 ABSTRACT The vast majority of bacteria in the environment have yet to be cultured. Consequently, a major proportion of both genetic diversity within known gene families and an unknown number of novel gene families reside in these uncultured organisms. Isolation of these genes is limited by lack of sequence information.
H W, Stokes +6 more
openaire +2 more sources
Methods and compositions for regulating gene expression in plant cells [PDF]
, 2010 Novel chimeric plant promoter sequences are provided, together with plant gene expression cassettes comprising such sequences. In certain preferred embodiments, the chimeric plant promoters comprise the BoxII cis element and/or derivatives thereof.
Beachy, Roger N. +2 more
core +1 more source
Gene transfer in the GI tract and oral cavity [PDF]
, 2000 Gene transfer is important in spreading antibiotic resistance and other traits such as virulence factors. In this review the molecular mechanisms of gene transfer are outlined and the biological consequences of bacterial gene transfer in the GI tract and
Mullany, P
core +1 more source