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Can Introns Stabilize Gene Duplication? [PDF]
Biology, 2022 Gene duplication is considered one of the most important events that determine the evolution of genomes. However, the neo-duplication condition of a given gene is particularly unstable due to recombination events. Several mechanisms have been proposed to
Gioacchino Micheli, Giorgio Camilloni
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Case report: A family of atypical hemolytic uremic syndrome involving a CFH::CFHR1 fusion gene and CFHR3-1-4-2 gene duplication [PDF]
Frontiers in ImmunologyMutations in the complement factor H (CFH) gene are associated with complement dysregulation and the development of atypical hemolytic uremic syndrome (aHUS).
Yuko Tasaki +10 more
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BMC Bioinformatics, 2022 Background Research on gene duplication is abundant and comes from a wide range of approaches, from high-throughput analyses and experimental evolution to bioinformatics and theoretical models.
Yuridia S. Posadas-García +1 more
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Frontiers in Cell and Developmental Biology, 2022 The process of gene duplication followed by gene loss or evolution of new functions has been studied extensively, yet the role gene duplication plays in the function and evolution of fertilization proteins is underappreciated.
Alberto M. Rivera, Willie J. Swanson
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Patterns of gene evolution following duplications and speciations in vertebrates [PDF]
PeerJ, 2020 Background Eukaryotic genes typically form independent evolutionary lineages through either speciation or gene duplication events. Generally, gene copies resulting from speciation events (orthologs) are expected to maintain similarity over time with ...
Kyle T. David +2 more
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BMC Genomics, 2023 Background In the evolutionary study of gene families, exploring the duplication mechanisms of gene families helps researchers understand their evolutionary history.
Huilong Chen +2 more
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Phylogenomics: gene duplication, unrecognized paralogy and outgroup choice. [PDF]
PLoS ONE, 2009 Comparative genomics has revealed the ubiquity of gene and genome duplication and subsequent gene loss. In the case of gene duplication and subsequent loss, gene trees can differ from species trees, thus frequent gene duplication poses a challenge for ...
Scott William Roy
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Duplicate Genes Contribute to Variability in Abiotic Stress Resistance in Allopolyploid Wheat
Plants, 2023 Gene duplication is a universal biological phenomenon that drives genomic variation and diversity, plays a crucial role in plant evolution, and contributes to innovations in genetic engineering and crop development.
Linying Du, Zhenbing Ma, Hude Mao
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Promoter evolution of mammalian gene duplicates
BMC Biology, 2023 Background Gene duplication is thought to be a central process in evolution to gain new functions. The factors that dictate gene retention following duplication as well paralog gene divergence in sequence, expression and function have been extensively ...
Evgeny Fraimovitch, Tzachi Hagai
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Acquisition of new function through gene duplication in the metallocarboxypeptidase family
Scientific Reports, 2023 Gene duplication is a key first step in the process of expanding the functionality of a multigene family. In order to better understand the process of gene duplication and its role in the formation of new enzymes, we investigated recent duplication ...
Daniel Fajardo +2 more
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