Parallel reorganization of protein function in the spindle checkpoint pathway through evolutionary paths in the fitness landscape that appear neutral in laboratory experiments. [PDF]
PLoS Genetics, 2017 Regulatory networks often increase in complexity during evolution through gene duplication and divergence of component proteins. Two models that explain this increase in complexity are: 1) adaptive changes after gene duplication, such as resolution of ...
Alex N Nguyen Ba +5 more
doaj +1 more source
Gene duplication and an accelerated evolutionary rate in 11S globulin genes are associated with higher protein synthesis in dicots as compared to monocots [PDF]
, 2012 Background: Seed storage proteins are a major source of dietary protein, and the content of such proteins determines both the quantity and quality of crop yield.
Dunwell, Jim +3 more
core +2 more sources
Frontiers in Pediatrics, 2021 Background: Very few reports are available on human XX ovotesticular disorder of sex development involving SOX3 gene duplication. Here we aim to present a rare case of SOX3 gene duplication in a person from the Chinese population who exhibits XX ...
Jianlong Zhuang +9 more
doaj +1 more source
Complexity Insights of the Minimum Duplication Problem [PDF]
, 2014 International audienceThe Minimum Duplication problem is a well-known problem in phylogenetics and comparative genomics. Given a set of gene trees, the Minimum Duplication problem asks for a species tree that induces the minimum number of gene ...
Blin, Guillaume +4 more
core +3 more sources
The multiple gene duplication problem revisited [PDF]
, 2008 Motivation: Deciphering the location of gene duplications and multiple gene duplication episodes on the Tree of Life is fundamental to understanding the way gene families and genomes evolve.
Blanc +15 more
core +4 more sources
Mitochondrial targeting adaptation of the hominoid-specific glutamate dehydrogenase driven by positive Darwinian selection [PDF]
, 2008 Many new gene copies emerged by gene duplication in hominoids, but little is known with respect to their functional evolution. Glutamate dehydrogenase (GLUD) is an enzyme central to the glutamate and energy metabolism of the cell.
A Courseaux +40 more
core +3 more sources
Altered patterns of gene duplication and differential gene gain and loss in fungal pathogens
BMC Genomics, 2008 Background Duplication, followed by fixation or random loss of novel genes, contributes to genome evolution. Particular outcomes of duplication events are possibly associated with pathogenic life histories in fungi.
Carbone Ignazio +4 more
doaj +1 more source
Tandem duplications lead to novel expression patterns through exon shuffling in Drosophila yakuba. [PDF]
PLoS Genetics, 2017 One common hypothesis to explain the impacts of tandem duplications is that whole gene duplications commonly produce additive changes in gene expression due to copy number changes.
Rebekah L Rogers +2 more
doaj +1 more source
Almost all human genes resulted from ancient duplication [PDF]
, 2006 Results of protein sequence comparison at open criterion show a very large number of relationships that have, up to now, gone unreported. The relationships suggest many ancient events of gene duplication. It is well known that gene duplication has been a
Castresana +3 more
core +2 more sources
Efficient Exploration of the Space of Reconciled Gene Trees [PDF]
, 2013 Gene trees record the combination of gene level events, such as duplication, transfer and loss, and species level events, such as speciation and extinction.
Boussau, Bastien +4 more
core +5 more sources