Results 51 to 60 of about 7,565,225 (388)
A novel evolutionary model for constructing gene coexpression networks with comprehensive features
BMC Bioinformatics, 2019 Background Uncovering the evolutionary principles of gene coexpression network is important for our understanding of the network topological property of new genes.
Yuexi Gu, Jian Zu, Yu Li
doaj +1 more source
Phylogeny Reconstruction Using Duplicate Genes [PDF]
Molecular Biology and Evolution, 2000 In this paper, we propose a new method (uninode coding) for coding duplicate (paralogous) genes to infer species trees. Uninode coding incorporates data from duplicated and unduplicated gene copies in phylogenetic analyses of taxa. Uninode coding utilizes global parsimony through the inclusion of both duplicated and unduplicated gene copies, allows one
M P, Simmons +2 more
openaire +2 more sources
Identifying and removing haplotypic duplication in primary genome assemblies
bioRxiv, 2019 Motivation Rapid development in long read sequencing and scaffolding technologies is accelerating the production of reference-quality assemblies for large eukaryotic genomes.
Dengfeng Guan +5 more
semanticscholar +1 more source
G3: Genes, Genomes, Genetics, 2017 Gene and genome duplication are the major sources of biological innovations in plants and animals. Functional and transcriptional divergence between the copies after gene duplication has been considered the main driver of innovations .
Florian Mattenberger +3 more
doaj +1 more source
Plant Direct, 2020 Polyploidization, or whole‐genome duplication, leads to gene expression changes that drive the evolution of many plants and some animals. However, the role of the dosage effect on gene expression changes following genome duplication remains unclear. Here,
Shouli Feng +6 more
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Structural properties of the reconciliation space and their applications in enumerating nearly-optimal reconciliations between a gene tree and a species tree [PDF]
, 2011 Introduction: A gene tree for a gene family is often discordant with the containing species tree because of its complex evolutionary course during which gene duplication, gene loss and incomplete lineage sorting events might occur.
Louxin Zhang, Taoyang Wu
core +2 more sources
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Detecting functional divergence after gene duplication through evolutionary changes in posttranslational regulatory sequences. [PDF]
PLoS Computational Biology, 2014 Gene duplication is an important evolutionary mechanism that can result in functional divergence in paralogs due to neo-functionalization or sub-functionalization.
Alex N Nguyen Ba +7 more
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Has gene duplication impacted the evolution of Eutherian longevity? [PDF]
, 2016 One of the greatest unresolved questions in aging biology is determining the genetic basis of interspecies longevity variation. Gene duplication is often the key to understanding the origin and evolution of important Eutherian phenotypes.
de Magalhaes, Joao Pedro, Doherty, Aoife
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source