Analysis of the Size of the Carcinoembryonic Antigen (CEA) Gene Family [PDF]
Five members of the human CEA gene family [human pregnancy-specific β1-glycoprotein (PSβG), hsCGM1, 2, 3 and 4] have been isolated and identified through sequencing the exons containing their N-terminal domains.
Beauchemin+30 more
core +1 more source
Distinguish between Duplication of Essential Genes and Duplication of Dispensable Genes [PDF]
AbstractWhen a dispensable gene is duplicated (ancestral dispensability), genetic buffering and duplicate compensation together maintain the gene dispensability, whereas duplicate compensation is the only mechanism when an essential gene is duplicated (ancestral essentiality).
openaire +2 more sources
Comparative Genomics Reveals Gene Duplication and Evolution in 26 Aurantioideae Species
Gene duplication, as a prevalent phenomenon in the tree of life, provides a potential substrate for evolution. However, its role in the Aurantioideae remains unclear.
Jiaxuan Liu+5 more
doaj +1 more source
The Evolutionary Relationship between Alternative Splicing and Gene Duplication
The protein diversity that exists today has resulted from various evolutionary processes. It is well known that gene duplication (GD) along with the accumulation of mutations are responsible, among other factors, for an increase in the number of ...
Luis P. Iñiguez, G. Hernández
semanticscholar +1 more source
Genome duplication and gene loss affect the evolution of heat shock transcription factor genes in legumes. [PDF]
Whole-genome duplication events (polyploidy events) and gene loss events have played important roles in the evolution of legumes. Here we show that the vast majority of Hsf gene duplications resulted from whole genome duplication events rather than ...
Yongxiang Lin+6 more
doaj +1 more source
Going nuclear: gene family evolution and vertebrate phylogeny reconciled [PDF]
Gene duplications have been common throughout vertebrate evolution, introducing paralogy and so complicating phylogenctic inference from nuclear genes.
James A. Cotton+6 more
core +4 more sources
Recurrent De Novo NAHR Reciprocal Duplications in the ATAD3 Gene Cluster Cause a Neurogenetic Trait with Perturbed Cholesterol and Mitochondrial Metabolism. [PDF]
Recent studies have identified both recessive and dominant forms of mitochondrial disease that result from ATAD3A variants. The recessive form includes subjects with biallelic deletions mediated by non-allelic homologous recombination.
Armstrong, C+28 more
core +3 more sources
Gene Duplication and Protein Evolution in Tick-Host Interactions
Ticks modulate their hosts' defense responses by secreting a biopharmacopiea of hundreds to thousands of proteins and bioactive chemicals into the feeding site (tick-host interface).
B. Mans+3 more
semanticscholar +1 more source
Gene duplication and the birthday problem [PDF]
Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/62607/1/296176a0 ...
openaire +4 more sources
A novel evolutionary model for constructing gene coexpression networks with comprehensive features
Background Uncovering the evolutionary principles of gene coexpression network is important for our understanding of the network topological property of new genes.
Yuexi Gu, Jian Zu, Yu Li
doaj +1 more source