Results 261 to 270 of about 8,339,405 (403)

CRISPR-directed exon skipping; friend or foe (opportunity or warning sign)?

Molecular Therapy: Nucleic Acids
Kelly H. Banas, Eric B. Kmiec
doaj   +1 more source

Editorial: Gene editing to achieve Zero Hunger. [PDF]

Front Genome Ed
Ahmad S, Rana IA, Folta KM, Lorenzo CD, Khan SH.   +4 more
europepmc   +1 more source

Editing a gibberellin receptor gene improves yield and nitrogen fixation in soybean [PDF]

J Tang, Shuhan Yang, S.-P. Li, Xiuli Yue, Ting Jin, Xinyu Yang, Kai Zhang, Qianqian Yang, T K Liu, Shancen Zhao, Junyi Gai, Yan Li   +11 more
openalex   +1 more source

sgRNA Sequence Motifs Blocking Efficient CRISPR/Cas9-Mediated Gene Editing [PDF]

, 2019
Robin Graf, Xun Li, Van Trung Chu, Klaus Rajewsky   +3 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Gene Editing and AI: Revolutionizing Biotechnology for a Sustainable Future. [PDF]

Iran J Biotechnol
europepmc   +1 more source

Making the impossible possible: Baby KJ and the road map to personalized gene-editing care. [PDF]

Clin Transl Med
Almendro V, Kassim SH.
europepmc   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Callus and endosperm green fluorescence reporter-assisted selection system in maize CRISPR/Cas9 gene editing. [PDF]

BMC Plant Biol
Ge L, Li W, Dou Y, Ma Y, Sun M, Chen X, Feng X, Li Y, Yu Q.   +8 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source