Results 61 to 70 of about 1,009,200 (260)
Switchable genome editing via genetic code expansion [PDF]
, 2018 Multiple applications of genome editing by CRISPR-Cas9 necessitate stringent regulation and Cas9 variants have accordingly been generated whose activity responds to small ligands, temperature or light.
Asami, Maki +5 more
core +2 more sources
Artificial and Natural Genetic Information Processing [PDF]
, 2017 Conventional methods of genetic engineering and more recent genome editing techniques focus on identifying genetic target sequences for manipulation.
Witzany, Guenther
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Heat increases the editing efficiency of human papillomavirus E2 gene by inducing upregulation of APOBEC3A and 3G [PDF]
, 2017 Apolipoprotein B mRNA-editing catalytic polypeptide (APOBEC) 3 proteins have been identified as potent viral DNA mutators and have broad antiviral activity.
Chen, Hongduo +9 more
core +1 more source
GARNet gene editing workshop [PDF]
New Phytologist, 2018 [No Abstract]
Geraint Parry, C. Jill Harrison
openaire +5 more sources
Functional rescue of dystrophin deficiency in mice caused by frameshift mutations using Campylobacter jejuni Cas9 [PDF]
, 2018 Duchenne muscular dystrophy (DMD) is a fatal, X-linked muscle wasting disease caused by mutations in the DMD gene. In 51% of DMD cases, a reading frame is disrupted because of deletion of several exons.
Cappellari, O +9 more
core +1 more source
Promise and challenges of gene editing [PDF]
Science, 2017 Crop Development With traditional plant breeding approaches, it can take a decade or more to develop a new crop. In a Perspective, Scheben and Edwards highlight recent efforts to use the gene editing technology CRISPR-Cas9 for faster plant breeding. This technology can yield an improved experimental crop in just one generation, but the genetic sequence
openaire +3 more sources
Viruses, 2023 Rapid progress in gene editing based on clustered regularly interspaced short palindromic repeats/CRISPR-associated protein (CRISPR/Cas) has revolutionized functional genomic studies and genetic disease correction.
Dmitriy Mazurov +2 more
doaj +1 more source
Gene Editing for the Treatment of Hypercholesterolemia
Current Atherosclerosis ReportsAbstract Purpose of Review Here, we summarize the key findings from preclinical studies that tested the concept that editing of hepatic genes can lower plasma low-density lipoprotein (LDL)-cholesterol levels to subsequently reduce atherosclerotic cardiovascular disease risk. Recent Findings
Hoekstra, M., Eck, M. van
openaire +3 more sources
Gene editing in veterinary pathophysiology [PDF]
Veterinary Quarterly, 2016 Dear reader,Veterinary Quarterly is an international journal publishing research in the field of animal diseases including their pathophysiology.
openaire +3 more sources
Promoter keyholes enable specific and persistent multi-gene expression programs in primary T cells without genome modification [PDF]
, 2020 Non-invasive epigenome editing is a promising strategy for engineering gene expression programs, yet potency, specificity, and persistence remain challenging.
Acosta, Reyes +25 more
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