Results 81 to 90 of about 6,790,032 (188)
The Quality of Ornamental Japanese Carp (Cyprinus Carpio Var. Koi) After Electroporation as a Gene Material Transfer Method [PDF]
, 2016 Spermatozoa are male gametes that have an advantage in acting as gene transfer media (SMGT), because in transferring genetic material, sperm uses relatively natural vectors.
Kilawati, Y. (Yuni) +2 more
core +2 more sources
Muscle &Nerve, Volume 72, Issue 1, Page 139-148, July 2025.ABSTRACT Introduction/Aims We previously demonstrated that leucine supplementation significantly reduces histone deacetylase 4 (HDAC4) expression induced by hindlimb immobilization, thereby attenuating the increase in HDAC4 protein levels and nuclear accumulation.
Paula K. N. Alves +6 more
wiley +1 more source
Education on electrical phenomena involved in electroporation-based therapies and treatments: a blended learning approach [PDF]
, 2016 BACKGROUND: Electroporation-based applications require multidisciplinary expertise and collaboration of experts with different professional backgrounds in engineering and science.
Damijan Miklavčič +2 more
core +1 more source
Dexamethasone Promotes Autophagy Dependent Ferroptosis of Placental Trophoblast Cells Through GRα
Journal of Cellular and Molecular Medicine, Volume 29, Issue 13, July 2025.ABSTRACT Dexamethasone (DEX) has been extensively employed for the treatment of pregnancy disorders related to preterm birth. However, the precise mechanism by which prenatal DEX exposure affects foetal development remains unclear. This study delves into investigating the influence of DEX and ferroptosis inhibitors on the activity and ferroptosis level
Junlei Lu +4 more
wiley +1 more source
Canstatin gene electrotransfer combined with radiotherapy: preclinical trials for cancer treatment [PDF]
Gene Therapy, 2008 Given as a prophylactic treatment, a single muscle electrogene transfer of plasmid coding canstatin fused to human serum albumin (CanHSA), slowed down the development of two xenografted human carcinomas from mammary (MDA-MB-231) and prostate origin (PC-3) in nude mice and delayed lung metastatic spreading of B16F10 melanoma cells in syngenic mice.
Magnon, C. +5 more
openaire +3 more sources
Modelling single cell electroporation with bipolar pulse parameters and dynamic pore radii [PDF]
, 2010 We develop a model of single spherical cell electroporation and simulate spatial and temporal aspects of the transmembrane potential and pore radii as an effect of any form of applied electric field.
Cree, Michael J. +3 more
core +2 more sources
Current Protocols, Volume 5, Issue 6, June 2025.Abstract Plant autophagy is a catabolic process where cellular components such as protein aggregates and dysfunctional organelles are degraded and recycled to maintain homeostasis and facilitate stress resilience. Autophagy relies on a double‐membrane vesicle called the autophagosome, which delivers cellular cargo to the vacuole for degradation.
William Agbemafle +2 more
wiley +1 more source
Defective Processing of Cytoplasmic and Chloroplast Ribosomal RNA in the Absence of Arabidopsis DXO1
Plant, Cell &Environment, Volume 48, Issue 6, Page 4227-4244, June 2025.ABSTRACT Decapping 5′‐3′ exoribonucleases from the DXO/Rai1 family are highly conserved among eukaryotes and exhibit diverse enzymatic activities depending on the organism. The biochemical and structural properties of the plant DXO1 differ from the yeast and animal counterparts, which is reflected in the in vivo functions of this enzyme.
Monika Zakrzewska‐Placzek +5 more
wiley +1 more source
Biphasic Gene Electrotransfer Enhances Gene Delivery In Vitro
, 2020 The application of short, pulsed electric fields to eukaryotic cells and tissues has been shown to permeabilize cells. This phenomenon has been used for clinical applications for irreversible electroporation of cancer cells or for molecule delivery for drug or gene therapies.
openaire +2 more sources
Tissue damage modeling in gene electrotransfer: The role of pH
Bioelectrochemistry, 2014 Optimal gene electrotransfer (GET) requires a compromise between maximum transgene expression and minimal tissue damage. GET in skeletal muscle can be improved by pretreatment with hyaluronidase which contributes to maximize transgene uptake and expression.
Olaiz N +7 more
openaire +5 more sources