Results 101 to 110 of about 2,519,482 (174)

20th Anniversary of the Department of Experimental Oncology at the Institute of Oncology Ljubljana

Onkologija
The twentieth anniversary of the Department of Experimental Oncology marks an important milestone in the history of research activities at the Institute of Oncology Ljubljana.
Gregor Serša , Ajda Medved , Jaka Vrevc Žlajpah , Maja Čemažar   +3 more
doaj   +1 more source

Optimisation of intradermal DNA electrotransfer for immunisation

, 2007
The development of DNA vaccines requires appropriate delivery technologies. Electrotransfer is one of the most efficient methods of non-viral gene transfer. In the present study, intradermal DNA electrotransfer was first optimised.
Staes, Edith, Bureau, Michel Francis, Vandermeulen, Gaëlle, Vanderhaeghen, Marie-Lise, Scherman, Daniel, Préat, Véronique   +5 more
core   +1 more source

The effectiveness of calcium electroporation combined with gene electrotransfer of a plasmid encoding IL-12 is tumor type-dependent. [PDF]

Front Immunol, 2023
Lisec B, Markelc B, Ursic Valentinuzzi K, Sersa G, Cemazar M.   +4 more
europepmc   +1 more source

Gene electrotransfer using porous membranes

, 2022
Genska elektrotransfekcija je ena izmed glavnih nevirusnih metod za dostavo plazmidne DNK v notranjost bioloških celic. Ta metoda temelji na pojavu elektroporacije, pri katerem se ob izpostavitvi celic pulzirajočemu električnemu polju začasno poveča ...
Vindiš, Tina
core  

DNA Electrotransfer: An Effective Tool for Gene Therapy

, 2013
Originally developed for monogenic diseases, and therefore associated with the compensa‐ tion of genes whose alteration is responsible for diseases, the concept of gene therapy has rapidly expanded to the use of DNA as a new type of drug. Therefore, gene therapy leads to indications which are far beyond the case of genetic diseases, since a DNA drug ...
Aurore Burgain-Chain, Daniel Scherm
openaire   +2 more sources

Efficient gene transfer by pulse parameters for electrochemotherapy of cells in vitro and in muscle and melanoma tumors in mice

Radiology and Oncology
In recent years, various gene therapy strategies have been developed for cancer treatment. One of these strategies is electroporation-based delivery of therapeutic transgenes - gene electrotransfer (GET). Electrochemotherapy and GET have been combined in
Omerzel Masa, Markelc Bostjan, Brezar Simona Kranjc, Sersa Gregor, Cemazar Maja   +4 more
doaj   +1 more source

Electrochemotherapy Plus IL-2+IL-12 Gene Electrotransfer in Spontaneous Inoperable Stage III-IV Canine Oral Malignant Melanoma. [PDF]

Vaccines (Basel), 2023
Tellado M, De Robertis M, Montagna D, Giovannini D, Salgado S, Michinski S, Signori E, Maglietti F.   +7 more
europepmc   +1 more source

Pulsed Electric Fields Induce STING Palmitoylation and Polymerization Independently of Plasmid DNA Electrotransfer

Pharmaceutics
Gene therapy approaches may target skeletal muscle due to its high protein-expressing nature and vascularization. Intramuscular plasmid DNA (pDNA) delivery via pulsed electric fields (PEFs) can be termed electroporation or electrotransfer.
Amanda Sales Conniff, Julie Singh, Richard Heller, Loree C. Heller   +3 more
doaj   +1 more source

Optical imaging of luminescence for quantification of gene electrotransfer in mouse muscle and knee-3

, 2011
Copyright information:Taken from "Optical imaging of luminescence for quantification of gene electrotransfer in mouse muscle and knee"BMC Biotechnology 2006;6():16-16.Published online 8 Mar 2006PMCID:PMC1431530.Copyright © 2006 Bloquel et al; licensee ...
J Seguin (56009), MF Bureau (56011), C Bloquel (56006), C Trollet (56007), E Pradines (56008), D Scherman (56010)   +5 more
core   +1 more source

A virus based vaccine combined with IL12 gene therapy eradicates aggressive melanoma

Scientific Reports
Our study introduces a novel bacteriophage-based vaccine strategy and evaluates its antitumor efficacy, both as a standalone therapy and in combination with gene electrotransfer (GET) of interleukin-12 (IL-12) plasmids. Using phage display technology, we
Nuša Brišar, Katja Šuster, Simona Kranjc Brezar, Andrej Cör   +3 more
doaj   +1 more source