Calcium Electroporation of Equine Sarcoids [PDF]
Animals, 2020 Sarcoids are common equine skin tumors where the risk of recurrence after treatment is high, and better treatment options are warranted. Calcium electroporation is a novel anti-cancer treatment where lethally high calcium concentrations are introduced ...
Julie Gehl, Trine Tramm
exaly +10 more sources
Effect of Calcium Electroporation in Combination With Metformin in Vivo and Correlation Between Viability and Intracellular ATP Level After Calcium Electroporation in Vitro [PDF]
PLoS ONE, 2017 BACKGROUND:Calcium electroporation is a new experimental anti-cancer treatment where calcium is internalized into cells by application of short, high voltage pulses.
Julie Gehl, Stine Krog Frandsen
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Endoscopic calcium electroporation for colorectal cancer: a phase I study [PDF]
Endoscopy International Open, 2023 Background and study aims Colorectal cancer is one of the most common malignancies, with approximately 20 % of patients having metastatic disease. Local symptoms from the tumor remain a common issue and affect quality of life.
Broholm Broholm +15 more
doaj +8 more sources
Calcium Electroporation Induces Tumor Eradication, Long-Lasting Immunity and Cytokine Responses in the CT26 Colon Cancer Mouse Model [PDF]
OncoImmunology, 2017 Electroporation is used in cancer treatment because of its ability to increase local cytotoxicity of e.g. bleomycin (electrochemotherapy) and calcium (calcium electroporation).
Patrick F Forde +2 more
exaly +4 more sources
An Explorative Study on Calcium Electroporation for Low-risk Basal Cell Carcinoma [PDF]
Acta Dermato-VenereologicaIn electrochemotherapy, permeabilization of the cell membrane by electric pulses increases the anti-tumour effect of chemotherapeutics. In calcium electroporation, chemotherapy is replaced by calcium chloride with obvious benefits.
Stine R. Wiegell +8 more
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Study protocol designed to investigate tumour response to calcium electroporation in cancers affecting the skin: a non-randomised phase II clinical trial [PDF]
BMJ Open, 2021 Introduction Skin malignancy is a distressing problem for many patients, and clinical management is challenging. This article describes the protocol for the Calcium Electroporation Response Study (CaEP-R) designed to investigate tumour response to ...
Julie Gehl +10 more
doaj +4 more sources
Calcium Electroporation for Management of Cutaneous Metastases in HER2-Positive Breast Cancer: A Case Report [PDF]
Case Reports in Dermatology, 2022 We report a case of successful treatment of cutaneous metastases in HER2-positive breast cancer with calcium electroporation (CaEP), in addition to trastuzumab, over a period of 5 years.
Katrine Borres Jensen +3 more
doaj +2 more sources
The effectiveness of calcium electroporation combined with gene electrotransfer of a plasmid encoding IL-12 is tumor type-dependent [PDF]
Frontiers in Immunology, 2023 IntroductionIn calcium electroporation (CaEP), electroporation enables the cellular uptake of supraphysiological concentrations of Ca2+, causing the induction of cell death. The effectiveness of CaEP has already been evaluated in clinical trials; however,
Barbara Lisec +8 more
doaj +2 more sources
Pioneering Endoscopic Calcium-Electroporation in Gastric Cancer: A Case Series of an Emerging Therapeutic Approach [PDF]
DiseasesBackground/Objectives: Gastric cancer often presents at advanced stages with complications such as iron-deficiency anemia (IDA) due to chronic bleeding, representing a significant global health burden.
Giuliano Francesco Bonura +9 more
doaj +2 more sources
Combination of irreversible and calcium electroporation to overcome heterogeneity-associated incomplete ablation in the pancreas [PDF]
Scientific ReportsIrreversible electroporation (IRE) can be considered as an alternative therapy for pancreatic tumors. However, a previous study revealed that the difference in electrical conductivity between the liver parenchyma and vessels was reported to result in ...
Min-Jung Ko, Hun-Young Yoon
doaj +2 more sources