Results 41 to 50 of about 652,107 (224)
NCLX Inhibition plus Ca<sup>2+</sup> Delivery Potentiates Electroporation and Antitumor Immunity in Pancreatic Ductal Adenocarcinoma. [PDF]
Adv Sci (Weinh)Electroporation combined with NCLX inhibition and Ca2+ delivery induces mitochondrial Ca2+ overload in PDAC cells, triggering pyroptosis, DAMP release, and antitumor immune activation. Simultaneously, suppression of tumor‐derived SPP1 weakens SPP1–CD44 signaling and remodels macrophages toward an antitumor phenotype, thereby enhancing CD8+ T‐cell ...
Zhao C +7 more
europepmc +2 more sources
Sensors, 2022 Membrane permeabilization stimulated by high-voltage electric pulses has been used to deliver cell-impermeable exogenous molecules. The electric field effect on the cells depends on various experimental parameters, such as electric field strength, the ...
Yuki Watanabe +5 more
doaj +1 more source
Electroporation and Electrochemotherapy in Gynecological and Breast Cancer Treatment
Molecules, 2022 Gynecological carcinomas affect an increasing number of women and are associated with poor prognosis. The gold standard treatment plan is mainly based on surgical resection and subsequent chemotherapy with cisplatin, 5-fluorouracil, anthracyclines, or ...
Zofia Łapińska +3 more
doaj +1 more source
Cell Electrosensitization Exists Only in Certain Electroporation Buffers. [PDF]
PLoS ONE, 2016 Electroporation-induced cell sensitization was described as the occurrence of a delayed hypersensitivity to electric pulses caused by pretreating cells with electric pulses.
Janja Dermol +3 more
doaj +1 more source
Membrane electroporation and direct gene transfer [PDF]
, 1992 Neumann E. Membrane electroporation and direct gene transfer. Bioelectrochemistry and Bioenergetics. 1992;28(1-2):247-267.The direct transfer of genetic material into cells by electroporation can be described in physicochemical terms as an ...
Eberhard Neumann, Neumann, Eberhard
core +1 more source
, 2023 Calcium electroporation as an adjunct therapy for pembrolizumab-resistant bladder cancer: a case ...
Lars Munch Larsen (16533235) +6 more
core +1 more source
Calcium electroporation in cutaneous metastases – A non-randomised phase II multicentre clinical trial [PDF]
European Journal of Surgical Oncology, 2023 Cutaneous metastases can cause distressing symptoms and be challenging to treat. Local therapies are essential in management. Calcium electroporation uses calcium and electrical pulses to selectively kill cancer cells. This multicentre study aimed to define response in cutaneous metastases across different cancer types.Patients with tumours ≤3 cm of ...
Mille Vissing +7 more
openaire +4 more sources
Pharmaceutics, 2020 Estrogens (Es) play a significant role in the carcinogenesis and progression of ovarian malignancies. Depending on the concentration, Es may have a protective or toxic effect on cells.
Zofia Łapińska +5 more
doaj +1 more source
Viability of H69 and SW780 cells after calcium electroporation.
, 2015 Viability, assessed using MTS assay, of H69, a human small cell lung cancer cell line (A); and SW780, a human bladder cancer cell line (B) 24 hours after treatment with calcium electroporation.
Emilie Louise Hansen (719076) +5 more
core +1 more source
U937 cell response to calcium electroporation.
, 2015 U937, a human leukaemia cell line. (A) Cellular quinacrine fluorescence intensity of U937 15 min after calcium electroporation. The extracellular quinacrine concentration was 10 μM during loading and electroporation.
Emilie Louise Hansen (719076) +5 more
core +1 more source