ESOPE-Equivalent Pulsing Protocols for Calcium Electroporation: An In Vitro Optimization Study on 2 Cancer Cell Models [PDF]
Technology in Cancer Research and Treatment, 2018 Olga Zeni +2 more
exaly +2 more sources
Applied Sciences, 2020 (1) Background: In the last two decades, anticancer treatment has been extensively developed based on various physical methods, including electroporation (EP).
Julia Rudno-Rudzińska +4 more
doaj +1 more source
Pharmaceutics, 2020 Electroporation—a transient electric-field-induced increase in cell membrane permeability—can be used to facilitate the delivery of anticancer drugs for antitumour electrochemotherapy.
Diana Navickaite +6 more
doaj +1 more source
Sensors, 2022 Membrane permeabilization stimulated by high-voltage electric pulses has been used to deliver cell-impermeable exogenous molecules. The electric field effect on the cells depends on various experimental parameters, such as electric field strength, the ...
Yuki Watanabe +5 more
doaj +1 more source
Calcium electroporation in three cell lines: a comparison of bleomycin and calcium, calcium compounds, and pulsing conditions [PDF]
Biochimica et Biophysica Acta (BBA) - General Subjects, 2014 Electroporation with calcium (calcium electroporation) can induce ATP depletion-associated cellular death. In the clinical setting, the cytotoxic drug bleomycin is currently used with electroporation (electrochemotherapy) for palliative treatment of tumors.
Stine Krog Frandsen +4 more
openaire +3 more sources
Electroporation and Electrochemotherapy in Gynecological and Breast Cancer Treatment
Molecules, 2022 Gynecological carcinomas affect an increasing number of women and are associated with poor prognosis. The gold standard treatment plan is mainly based on surgical resection and subsequent chemotherapy with cisplatin, 5-fluorouracil, anthracyclines, or ...
Zofia Łapińska +3 more
doaj +1 more source
Calcium electroporation for treatment of cutaneous metastases; a randomized double-blinded phase II study, comparing the effect of calcium electroporation with electrochemotherapy [PDF]
Acta Oncologica, 2017 Calcium electroporation is a novel anticancer treatment, which utilizes high voltage pulses to permeabilize cell membranes and expose the cell to supraphysiological doses of calcium. Preclinical studies on calcium electroporation have shown strikingly high tumor response with cell necrosis.
H. Falk +3 more
openaire +3 more sources
Cell Electrosensitization Exists Only in Certain Electroporation Buffers. [PDF]
PLoS ONE, 2016 Electroporation-induced cell sensitization was described as the occurrence of a delayed hypersensitivity to electric pulses caused by pretreating cells with electric pulses.
Janja Dermol +3 more
doaj +1 more source
Calcium electroporation in cutaneous metastases – A non-randomised phase II multicentre clinical trial [PDF]
European Journal of Surgical Oncology, 2023 Cutaneous metastases can cause distressing symptoms and be challenging to treat. Local therapies are essential in management. Calcium electroporation uses calcium and electrical pulses to selectively kill cancer cells. This multicentre study aimed to define response in cutaneous metastases across different cancer types.Patients with tumours ≤3 cm of ...
Mille Vissing +7 more
openaire +4 more sources
Pharmaceutics, 2020 Estrogens (Es) play a significant role in the carcinogenesis and progression of ovarian malignancies. Depending on the concentration, Es may have a protective or toxic effect on cells.
Zofia Łapińska +5 more
doaj +1 more source