Results 81 to 90 of about 4,599 (157)

Tumor Radiosensitization by Gene Electrotransfer-Mediated Double Targeting of Tumor Vasculature. [PDF]

Int J Mol Sci, 2023
Savarin M, Znidar K, Sersa G, Komel T, Cemazar M, Kamensek U.   +5 more
europepmc   +1 more source

What We Learned about the Feasibility of Gene Electrotransfer for Vaccination on a Model of COVID-19 Vaccine. [PDF]

Pharmaceutics, 2023
Kamensek U, Cemazar M, Kranjc Brezar S, Jesenko T, Kos S, Znidar K, Markelc B, Modic Z, Komel T, Gorse T, Rebersek E, Jakopic H, Sersa G.   +12 more
europepmc   +1 more source

Design, Development, and Testing of a Device for Gene Electrotransfer to Skin Cells In Vivo. [PDF]

Pharmaceutics, 2022
Cvetkoska A, Dermol-Černe J, Miklavčič D, Kranjc Brezar S, Markelc B, Serša G, Reberšek M.   +6 more
europepmc   +1 more source

20th Anniversary of the Department of Experimental Oncology at the Institute of Oncology Ljubljana

Onkologija
The twentieth anniversary of the Department of Experimental Oncology marks an important milestone in the history of research activities at the Institute of Oncology Ljubljana.
Gregor Serša , Ajda Medved , Jaka Vrevc Žlajpah , Maja Čemažar   +3 more
doaj   +1 more source

Gene Electrotransfer Efficiency in 2D and 3D Cancer Cell Models Using Different Electroporation Protocols: A Comparative Study. [PDF]

Pharmaceutics, 2023
de Caro A, Bellard E, Kolosnjaj-Tabi J, Golzio M, Rols MP.   +4 more
europepmc   +1 more source

The effectiveness of calcium electroporation combined with gene electrotransfer of a plasmid encoding IL-12 is tumor type-dependent. [PDF]

Front Immunol, 2023
Lisec B, Markelc B, Ursic Valentinuzzi K, Sersa G, Cemazar M.   +4 more
europepmc   +1 more source

Electrochemotherapy Plus IL-2+IL-12 Gene Electrotransfer in Spontaneous Inoperable Stage III-IV Canine Oral Malignant Melanoma. [PDF]

Vaccines (Basel), 2023
Tellado M, De Robertis M, Montagna D, Giovannini D, Salgado S, Michinski S, Signori E, Maglietti F.   +7 more
europepmc   +1 more source

DNA Electrotransfer: An Effective Tool for Gene Therapy

, 2013
Originally developed for monogenic diseases, and therefore associated with the compensa‐ tion of genes whose alteration is responsible for diseases, the concept of gene therapy has rapidly expanded to the use of DNA as a new type of drug. Therefore, gene therapy leads to indications which are far beyond the case of genetic diseases, since a DNA drug ...
Aurore Burgain-Chain, Daniel Scherm
openaire   +2 more sources

Efficient gene transfer by pulse parameters for electrochemotherapy of cells in vitro and in muscle and melanoma tumors in mice

Radiology and Oncology
In recent years, various gene therapy strategies have been developed for cancer treatment. One of these strategies is electroporation-based delivery of therapeutic transgenes - gene electrotransfer (GET). Electrochemotherapy and GET have been combined in
Omerzel Masa, Markelc Bostjan, Brezar Simona Kranjc, Sersa Gregor, Cemazar Maja   +4 more
doaj   +1 more source

Pulsed Electric Fields Induce STING Palmitoylation and Polymerization Independently of Plasmid DNA Electrotransfer

Pharmaceutics
Gene therapy approaches may target skeletal muscle due to its high protein-expressing nature and vascularization. Intramuscular plasmid DNA (pDNA) delivery via pulsed electric fields (PEFs) can be termed electroporation or electrotransfer.
Amanda Sales Conniff, Julie Singh, Richard Heller, Loree C. Heller   +3 more
doaj   +1 more source