Results 1 to 10 of about 504,861 (113)

Shaping bacterial gene expression by physiological and proteome allocation constraints

open access: yesNature Reviews Microbiology, 2022
Networks of molecular regulators are often the primary objects of focus in the study of gene regulation, with the machinery of protein synthesis tacitly relegated to the background.
Terence Hwa   +2 more
exaly   +2 more sources

Post-transcriptional regulation of gene expression in bacterial pathogens by toxin-antitoxin systems

open access: yesFrontiers in Cellular and Infection Microbiology, 2014
Toxin-antitoxin (TA) systems are small genetic elements ubiquitous in prokaryotic genomes that encode toxic proteins targeting various vital cellular functions.
Ralph eBertram, Christopher F Schuster
doaj   +2 more sources

Dynamics of immune system gene expression upon bacterial challenge and wounding in a social insect (Bombus terrestris). [PDF]

open access: yesPLoS ONE, 2011
The innate immune system which helps individuals to combat pathogens comprises a set of genes representing four immune system pathways (Toll, Imd, JNK and JAK/STAT). There is a lack of immune genes in social insects (e.g.
Silvio Erler   +2 more
doaj   +3 more sources

Diversity and Versatility in Small RNA-Mediated Regulation in Bacterial Pathogens

open access: yesFrontiers in Microbiology, 2021
Bacterial gene expression is under the control of a large set of molecules acting at multiple levels. In addition to the transcription factors (TFs) already known to be involved in global regulation of gene expression, small regulatory RNAs (sRNAs) are ...
Brice Felden, Yoann Augagneur
doaj   +2 more sources

Implications of gene expression heterogeneity in the interplay between acquired resistance and bacterial metabolism

open access: yesScientific Reports
Gene expression heterogeneity has an impact on human bacterial pathogens responses, including antimicrobial resistance genes expression. Promoter region variability in resistance genes may include different regulatory boxes involved in metabolic ...
María Romero-Muñoz   +6 more
doaj   +2 more sources

Identification of BvgA-Dependent and BvgA-Independent Small RNAs (sRNAs) in Bordetella pertussis Using the Prokaryotic sRNA Prediction Toolkit ANNOgesic

open access: yesMicrobiology Spectrum, 2021
Noncoding small RNAs (sRNAs) are crucial for the posttranscriptional regulation of gene expression in all organisms and are known to be involved in the regulation of bacterial virulence.
Kyung Moon   +12 more
doaj   +1 more source

Conformational change of the Bordetella response regulator BvgA accompanies its activation of the B. pertussis virulence gene fhaB

open access: yesComputational and Structural Biotechnology Journal, 2022
The BvgAS two-component system regulates virulence gene expression in Bordetella pertussis. Although precise three-dimensional structural information is not available for the response regulator BvgA, its sequence conservation with E.
David Kim   +12 more
doaj   +1 more source

Status quo of tet regulation in bacteria

open access: yesMicrobial Biotechnology, 2022
Summary The tetracycline repressor (TetR) belongs to the most popular, versatile and efficient transcriptional regulators used in bacterial genetics. In the tetracycline (Tc) resistance determinant tet(B) of transposon Tn10, tetR regulates the expression
Ralph Bertram   +2 more
doaj   +1 more source

Optimized gene expression from bacterial chromosome by high-throughput integration and screening

open access: yesScience Advances, 2020
Pathway gene expression from the chromosome is optimized by a method of random site integrations and high-throughput screening. Chromosomal integration of recombinant genes is desirable compared with expression from plasmids due to increased stability ...
T. Saleski   +5 more
semanticscholar   +1 more source

Algorithm for the Reconstruction of Mathematical Frame Models of Bacterial Transcription Regulation

open access: yesMathematics, 2022
Transcription regulation plays an important role in bacterial activity. The operon concept coined by François Jacob and Jacques Monod has had a considerable effect on investigations into gene expression regulation, including modeling.
Tatiana N. Lakhova   +5 more
doaj   +1 more source

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