Results 1 to 10 of about 1,060,384 (258)

Exposure of Bifidobacterium longum subsp. infantis to Milk Oligosaccharides Increases Adhesion to Epithelial Cells and Induces a Substantial Transcriptional Response [PDF]

, 2013
Devon Kavanaugh is in receipt of a Teagasc Walsh Fellowship. The authors would also like to acknowledge the support of Science Foundation Ireland under Grant No.
Butto, Ludovica F., Clyne, Marguerite, Hickey, Rita M., Joshi, Lokesh, Kane, Marian, Kavanaugh, Devon W., Lane, Jonathan, O'Callaghan, John, Slattery, Helen   +8 more
core   +24 more sources

Optimized gene expression from bacterial chromosome by high-throughput integration and screening

Science Advances, 2020
Pathway gene expression from the chromosome is optimized by a method of random site integrations and high-throughput screening. Chromosomal integration of recombinant genes is desirable compared with expression from plasmids due to increased stability ...
T. Saleski, M. Chung, David N. Carruthers, Azzaya Khasbaatar, K. Kurabayashi, X. Lin   +5 more
semanticscholar   +1 more source

Metabolic regulation of gene expression by histone lactylation

Nature, 2019
The Warburg effect, which originally described increased production of lactate in cancer, is associated with diverse cellular processes such as angiogenesis, hypoxia, polarization of macrophages and activation of T cells.
Di Zhang, Zhanyun Tang, He Huang, He Huang, Guolin Zhou, Chang Cui, Yejing Weng, Wenchao Liu, Sunjoo Kim, Sangkyu Lee, Mathew Perez-Neut, Jun Ding, Daniel M. Czyż, Rong Hu, Z. Ye, Maomao He, Y. G. Zheng, H. Shuman, Lunzhi Dai, Lunzhi Dai, B. Ren, R. Roeder, L. Becker, Yingming Zhao   +23 more
semanticscholar   +1 more source

Regulation of Bacterial Gene Expression by Transcription Attenuation

Microbiology and Molecular Biology Reviews, 2019
A wide variety of mechanisms that control gene expression in bacteria are based on conditional transcription termination. Generally, in these mechanisms, a transcription terminator is located between a promoter and a downstream gene(s), and the ...
C. Turnbough
semanticscholar   +1 more source

The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7 [PDF]

, 2014
Classical studies have focused on the role that individual regulators play in controlling virulence gene expression. An emerging theme, however, is that bacterial metabolism also plays a key role in this process.
Abernathy, Anders, Baumler, Bergman, Boehm, Booth, Campellone, Chevance, Clark, Coburn, Creek, Echave, Elliott, Emmerson, Frankel, Fukuda, Fukuda, Hansen, Hartland, Hayashi, Hu, Hu, Hueck, Iyoda, Kendall, Kuhn, Mahajan, Massé, Minato, Nataro, Naylor, Noris, Paul, Porter, Rietsch, Rietsch, Ritchie, Ritchie, Roe, Roe, Scheltema, Shevchenko, Smith, Soutourina, Sullivan, Sánchez-Sanmarti, Thao, Tobe, Tree, Turner, Vytvytska, Wang, Wang, Weinert, Wolfe, Wolfe, Wolfe, Zhang, Zhao, Zumbrun   +59 more
core   +2 more sources

Genome wide expression profiling reveals suppression of host defence responses during colonisation by Neisseria meningitides but not N. lactamica. [PDF]

, 2011
Both Neisseria meningitidis and the closely related bacterium Neisseria lactamica colonise human nasopharyngeal mucosal surface, but only N. meningitidis invades the bloodstream to cause potentially life-threatening meningitis and septicaemia.
Hibberd, Martin L, Kroll, J Simon, Langford, Paul R, Li, Ming-Shi, Wong, Hazel En En   +4 more
core   +1 more source

Characterisation of the effects of salicylidene acylhydrazide compounds on type three secretion in Escherichia coli O157:H7 [PDF]

, 2009
Recent work has highlighted a number of compounds that target bacterial virulence by affecting gene regulation. In this work, we show that small-molecule inhibitors affect the expression of the type III secretion system (T3SS) of <i>Escherichia ...
Elofsson, M., Gally, D.L., Houghton, I., Layton, A., Mahajan, A., McInally, C., Roe, A.J., Stevens, M.P., Tree, J.J., Wang, D.   +9 more
core   +3 more sources

Interaction of two photoreceptors in the regulation of bacterial photosynthesis genes [PDF]

, 2012
The expression of photosynthesis genes in the facultatively photosynthetic bacterium Rhodobacter sphaeroides is controlled by the oxygen tension and by light quantity. Two photoreceptor proteins, AppA and CryB, have been identified in the past, which are
Frühwirth, Sebastian, Haberzettl, Kerstin, Hasewinkel, Christian, Klug, Gabriele, Metz, Sebastian, Teich, Kristin   +5 more
core   +1 more source

Trans-Acting Small RNAs and Their Effects on Gene Expression in Escherichia coli and Salmonella enterica

EcoSal Plus, 2020
The last few decades have led to an explosion in our understanding of the major roles that small regulatory RNAs (sRNAs) play in regulatory circuits and the responses to stress in many bacterial species. Much of the foundational work was carried out with
Jens Hör, G. Matera, J. Vogel, S. Gottesman, G. Storz   +4 more
semanticscholar   +1 more source

Intestinal gene expression in pigs: effects of reduced feed intake during weaning and potential impact of dietary components [PDF]

, 2011
The weaning transition is characterised by morphological, histological and microbial changes, often leading to weaning-associated disorders. These intestinal changes can partly be ascribed to the lack of luminal nutrition arising from the reduced feed ...
Bauer, E., Metzler-Zebeli, B.U., Mosenthin, R., Verstegen, M.W.A.   +3 more
core   +1 more source