Post-transcriptional regulation of gene expression in bacterial pathogens by toxin-antitoxin systems [PDF]
Frontiers in Cellular and Infection Microbiology, 2014 Toxin-antitoxin (TA) systems are small genetic elements ubiquitous in prokaryotic genomes that encode toxic proteins targeting various vital cellular functions.
Ralph eBertram, Christopher F Schuster
doaj +6 more sources
Regulation of Bacterial Gene Expression by Transcription Attenuation [PDF]
Microbiology and Molecular Biology Reviews, 2019 A wide variety of mechanisms that control gene expression in bacteria are based on conditional transcription termination. Generally, in these mechanisms, a transcription terminator is located between a promoter and a downstream gene(s), and the ...
C. Turnbough
semanticscholar +4 more sources
Dissecting specific and global transcriptional regulation of bacterial gene expression
Molecular Systems Biology, 2013 Gene expression is regulated by specific transcriptional circuits but also by the global expression machinery as a function of growth. Simultaneous specific and global regulation thus constitutes an additional—but often neglected—layer of complexity in ...
Luca Gerosa +3 more
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Regulation of bacterial virulence gene expression by cell envelope stress responses [PDF]
Virulence, 2014 The bacterial cytoplasm lies within a multilayered envelope that must be protected from internal and external hazards. This protection is provided by cell envelope stress responses (ESRs), which detect threats and reprogram gene expression to ensure ...
Josué Flores-Kim, A. Darwin
semanticscholar +4 more sources
Post-transcriptional regulation of gene expression in Yersinia species
Frontiers in Cellular and Infection Microbiology, 2012 Proper regulation of gene expression is required by bacterial pathogens to respond to continually changing environmental conditions and the host response during the infectious process.
Chelsea A Schiano, Wyndham W Lathem
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Transcriptional regulation of bacterial virulence gene expression by molecular oxygen and nitric oxide [PDF]
Virulence, 2014 Molecular oxygen (O2) and nitric oxide (NO) are diatomic gases that play major roles in infection. The host innate immune system generates reactive oxygen species and NO as bacteriocidal agents and both require O2 for their production.
Jeffrey Green, M. Rolfe, Laura. J. Smith
semanticscholar +4 more sources
Virulence Regulation in Borrelia burgdorferi [PDF]
MicroorganismsBorrelia burgdorferi, the causative agent of Lyme disease, is the most common vector-borne disease in the United States. Compared with other bacterial pathogens, B. burgdorferi has many unique features.
Sierra George, Zhiming Ouyang
doaj +2 more sources
Diversity and Versatility in Small RNA-Mediated Regulation in Bacterial Pathogens
Frontiers in Microbiology, 2021 Bacterial gene expression is under the control of a large set of molecules acting at multiple levels. In addition to the transcription factors (TFs) already known to be involved in global regulation of gene expression, small regulatory RNAs (sRNAs) are ...
Brice Felden, Yoann Augagneur
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The Role of Bacteriophage-Derived Small RNA Molecules in Bacterial and Phage Interactions [PDF]
VirusesSmall regulatory RNAs (sRNAs) play a critical role in bacterial gene expression, modulating various cellular processes, including stress responses, metabolism, virulence, and many others.
Natalia Lewandowska +5 more
doaj +2 more sources
MicroRNA-762 is upregulated in human corneal epithelial cells in response to tear fluid and Pseudomonas aeruginosa antigens and negatively regulates the expression of host defense genes encoding RNase7 and ST2. [PDF]
, 2013 Mucosal surfaces regulate defenses against infection and excessive inflammation. We previously showed that human tears upregulated epithelial expression of genes encoding RNase7 and ST2, which inhibited Pseudomonas aeruginosa invasion of human corneal ...
Chan, Gary +5 more
core +26 more sources