Results 1 to 10 of about 402,356 (116)

Dynamics of immune system gene expression upon bacterial challenge and wounding in a social insect (Bombus terrestris). [PDF]

PLoS ONE, 2011
The innate immune system which helps individuals to combat pathogens comprises a set of genes representing four immune system pathways (Toll, Imd, JNK and JAK/STAT). There is a lack of immune genes in social insects (e.g.
Silvio Erler, Mario Popp, H Michael G Lattorff   +2 more
doaj   +3 more sources

Escherichia coli hns and methylglyoxal link gut microbial metabolism to host neuronal gene regulation in Parkinson’s disease [PDF]

Gut Microbes
Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by dopaminergic neuron loss in the substantia nigra (SN). Although the gut microbiota has been implicated in PD pathogenesis, how defined bacterial genes and their ...
Min-Gi Shin, Soo Jung Park, Woorim Kang, Yiseul Bae, Suyeon Kim, Dayeong Yoo, Seoyeon Yoon, Sang Myun Park, Eun-Soo Kwon, Jaerak Chang, Jung Han Yoon, Don Gueu Park, Eun Jeong Lee   +12 more
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Implications of gene expression heterogeneity in the interplay between acquired resistance and bacterial metabolism

Scientific Reports
Gene expression heterogeneity has an impact on human bacterial pathogens responses, including antimicrobial resistance genes expression. Promoter region variability in resistance genes may include different regulatory boxes involved in metabolic ...
María Romero-Muñoz, Marina R. Pulido, Esther Recacha, Sara Díaz-Díaz, Marina Murillo-Torres, Fernando Docobo-Pérez, José Manuel Rodríguez-Martínez   +6 more
doaj   +2 more sources

Chloramphenicol-mobilized Bacillus subtilis transiently expresses resistance to multiple antibiotics, including the glycopeptides phleomycin and bleomycin [PDF]

Journal of Bacteriology
Antibiotic resistance presents an urgent global crisis, exacerbated by antibiotic overuse. Understanding the regulation of resistance genes within bacterial populations can inform strategies to prevent the spread of antibiotic resistance, and reveal how ...
Amelia Brave, Sandra LaBonte, Yongjin Liu, Morgan Powers, Evan De Ford, Paul D. Straight   +5 more
doaj   +2 more sources

Identification of BvgA-Dependent and BvgA-Independent Small RNAs (sRNAs) in Bordetella pertussis Using the Prokaryotic sRNA Prediction Toolkit ANNOgesic

Microbiology Spectrum, 2021
Noncoding small RNAs (sRNAs) are crucial for the posttranscriptional regulation of gene expression in all organisms and are known to be involved in the regulation of bacterial virulence.
Kyung Moon, Minji Sim, Chin-Hsien Tai, Kyungyoon Yoo, Charlotte Merzbacher, Sung-Huan Yu, David D. Kim, Jaehyun Lee, Konrad U. Förstner, Qing Chen, Scott Stibitz, Leslie G. Knipling, Deborah M. Hinton   +12 more
doaj   +1 more source

Conformational change of the Bordetella response regulator BvgA accompanies its activation of the B. pertussis virulence gene fhaB

Computational and Structural Biotechnology Journal, 2022
The BvgAS two-component system regulates virulence gene expression in Bordetella pertussis. Although precise three-dimensional structural information is not available for the response regulator BvgA, its sequence conservation with E.
David Kim, John Tracey, Manuel Becerra Flores, Kanita Chaudhry, Rafae Nasim, Abraham Correa-Medina, Leslie Knipling, Qing Chen, Scott Stibitz, Lisa M.M. Jenkins, Kyung Moon, Tim Cardozo, Deborah M. Hinton   +12 more
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Status quo of tet regulation in bacteria

Microbial Biotechnology, 2022
Summary The tetracycline repressor (TetR) belongs to the most popular, versatile and efficient transcriptional regulators used in bacterial genetics. In the tetracycline (Tc) resistance determinant tet(B) of transposon Tn10, tetR regulates the expression
Ralph Bertram, Bernd Neumann, Christopher F. Schuster   +2 more
doaj   +1 more source

Algorithm for the Reconstruction of Mathematical Frame Models of Bacterial Transcription Regulation

Mathematics, 2022
Transcription regulation plays an important role in bacterial activity. The operon concept coined by François Jacob and Jacques Monod has had a considerable effect on investigations into gene expression regulation, including modeling.
Tatiana N. Lakhova, Fedor V. Kazantsev, Aleksey M. Mukhin, Nikolay A. Kolchanov, Yury G. Matushkin, Sergey A. Lashin   +5 more
doaj   +1 more source

An Adaptable and Modular Set of Laboratory Exercises Connecting Genotype to Phenotype in Sporulating Bacillus subtilis

Journal of Microbiology & Biology Education, 2021
Practical lab exercises that help students draw connections between genotype and phenotype, and make and test predictions about the identity of mutants, are invaluable in college-level cell biology, genetics, and microbiology courses. While many bacteria
Anna L. McLoon, Amy H. Camp, Lilah Rahn-Lee   +2 more
doaj   +1 more source

Epigenetic silencing of host cell defense genes enhances intracellular survival of the rickettsial pathogen Anaplasma phagocytophilum. [PDF]

PLoS Pathogens, 2009
Intracellular bacteria have evolved mechanisms that promote survival within hostile host environments, often resulting in functional dysregulation and disease.
Jose C Garcia-Garcia, Nicole C Barat, Sarah J Trembley, J Stephen Dumler   +3 more
doaj   +1 more source