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Post-transcriptional regulation of gene expression in bacterial pathogens by toxin-antitoxin systems [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2014
Toxin-antitoxin (TA) systems are small genetic elements ubiquitous in prokaryotic genomes that encode toxic proteins targeting various vital cellular functions.
Ralph eBertram, Christopher F Schuster
doaj   +5 more sources

Regulation of Bacterial Gene Expression by Transcription Attenuation [PDF]

open access: yesMicrobiology and Molecular Biology Reviews, 2019
A wide variety of mechanisms that control gene expression in bacteria are based on conditional transcription termination. Generally, in these mechanisms, a transcription terminator is located between a promoter and a downstream gene(s), and the ...
C. Turnbough
semanticscholar   +3 more sources

Mode of regulation and the insulation of bacterial gene expression. [PDF]

open access: yesMolecular Cell, 2012
A gene can be said to be insulated from environmental variations if its expression level depends only on its cognate inducers, and not on variations in conditions. We tested the insulation of the lac promoter of E. coli and of synthetic constructs in which the transcription factor CRP acts as either an activator or a repressor, by measuring their input
Vered Sasson   +4 more
semanticscholar   +3 more sources

Regulation of bacterial virulence gene expression by cell envelope stress responses [PDF]

open access: yesVirulence, 2014
The bacterial cytoplasm lies within a multilayered envelope that must be protected from internal and external hazards. This protection is provided by cell envelope stress responses (ESRs), which detect threats and reprogram gene expression to ensure ...
Josué Flores-Kim, A. Darwin
semanticscholar   +3 more sources

Dissecting specific and global transcriptional regulation of bacterial gene expression

open access: yesMolecular Systems Biology, 2013
Gene expression is regulated by specific transcriptional circuits but also by the global expression machinery as a function of growth. Simultaneous specific and global regulation thus constitutes an additional—but often neglected—layer of complexity in ...
Luca Gerosa   +3 more
doaj   +4 more sources

Transcriptional regulation of bacterial virulence gene expression by molecular oxygen and nitric oxide [PDF]

open access: yesVirulence, 2014
Molecular oxygen (O2) and nitric oxide (NO) are diatomic gases that play major roles in infection. The host innate immune system generates reactive oxygen species and NO as bacteriocidal agents and both require O2 for their production.
Jeffrey Green, M. Rolfe, Laura. J. Smith
semanticscholar   +4 more sources

Post-transcriptional regulation of gene expression in Yersinia species

open access: yesFrontiers in Cellular and Infection Microbiology, 2012
Proper regulation of gene expression is required by bacterial pathogens to respond to continually changing environmental conditions and the host response during the infectious process.
Chelsea A Schiano, Wyndham W Lathem
doaj   +2 more sources

Diversity and Versatility in Small RNA-Mediated Regulation in Bacterial Pathogens

open access: yesFrontiers in Microbiology, 2021
Bacterial gene expression is under the control of a large set of molecules acting at multiple levels. In addition to the transcription factors (TFs) already known to be involved in global regulation of gene expression, small regulatory RNAs (sRNAs) are ...
Brice Felden, Yoann Augagneur
doaj   +2 more sources

Oxygen intervention in the regulation of gene expression: the photosynthetic bacterial paradigm

open access: yesCellular and Molecular Life Sciences (CMLS), 2004
The means by which oxygen intervenes in gene expression has been examined in considerable detail in the metabolically versatile bacterium Rhodobacter sphaeroides. Three regulatory systems are now known in this organism, which are used singly and in combination to modulate genes in response to changing oxygen availability.
J. Zeilstra-Ryalls, S. Kaplan
semanticscholar   +3 more sources

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