Results 1 to 10 of about 620,853 (205)

The Role of Bacteriophage-Derived Small RNA Molecules in Bacterial and Phage Interactions [PDF]

open access: yesViruses
Small regulatory RNAs (sRNAs) play a critical role in bacterial gene expression, modulating various cellular processes, including stress responses, metabolism, virulence, and many others.
Natalia Lewandowska   +5 more
doaj   +2 more sources

Dissecting specific and global transcriptional regulation of bacterial gene expression

open access: yesMolecular Systems Biology, 2013
Gene expression is regulated by specific transcriptional circuits but also by the global expression machinery as a function of growth. Simultaneous specific and global regulation thus constitutes an additional—but often neglected—layer of complexity in ...
Luca Gerosa   +3 more
doaj   +5 more sources

Post-transcriptional regulation of gene expression in bacterial pathogens by toxin-antitoxin systems [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2014
Toxin-antitoxin (TA) systems are small genetic elements ubiquitous in prokaryotic genomes that encode toxic proteins targeting various vital cellular functions.
Ralph eBertram, Christopher F Schuster
doaj   +5 more sources

Identification of BvgA-Dependent and BvgA-Independent Small RNAs (sRNAs) in Bordetella pertussis Using the Prokaryotic sRNA Prediction Toolkit ANNOgesic

open access: yesMicrobiology Spectrum, 2021
Noncoding small RNAs (sRNAs) are crucial for the posttranscriptional regulation of gene expression in all organisms and are known to be involved in the regulation of bacterial virulence.
Kyung Moon   +12 more
doaj   +1 more source

Status quo of tet regulation in bacteria

open access: yesMicrobial Biotechnology, 2022
Summary The tetracycline repressor (TetR) belongs to the most popular, versatile and efficient transcriptional regulators used in bacterial genetics. In the tetracycline (Tc) resistance determinant tet(B) of transposon Tn10, tetR regulates the expression
Ralph Bertram   +2 more
doaj   +1 more source

Mode of Regulation and the Insulation of Bacterial Gene Expression [PDF]

open access: yesMolecular Cell, 2012
A gene can be said to be insulated from environmental variations if its expression level depends only on its cognate inducers, and not on variations in conditions. We tested the insulation of the lac promoter of E. coli and of synthetic constructs in which the transcription factor CRP acts as either an activator or a repressor, by measuring their input
Vered Sasson   +4 more
openaire   +3 more sources

Algorithm for the Reconstruction of Mathematical Frame Models of Bacterial Transcription Regulation

open access: yesMathematics, 2022
Transcription regulation plays an important role in bacterial activity. The operon concept coined by François Jacob and Jacques Monod has had a considerable effect on investigations into gene expression regulation, including modeling.
Tatiana N. Lakhova   +5 more
doaj   +1 more source

An Adaptable and Modular Set of Laboratory Exercises Connecting Genotype to Phenotype in Sporulating Bacillus subtilis

open access: yesJournal of Microbiology & Biology Education, 2021
Practical lab exercises that help students draw connections between genotype and phenotype, and make and test predictions about the identity of mutants, are invaluable in college-level cell biology, genetics, and microbiology courses. While many bacteria
Anna L. McLoon   +2 more
doaj   +1 more source

Epigenetic silencing of host cell defense genes enhances intracellular survival of the rickettsial pathogen Anaplasma phagocytophilum. [PDF]

open access: yesPLoS Pathogens, 2009
Intracellular bacteria have evolved mechanisms that promote survival within hostile host environments, often resulting in functional dysregulation and disease.
Jose C Garcia-Garcia   +3 more
doaj   +1 more source

Relationship between the Chromosome Structural Dynamics and Gene Expression—A Chicken and Egg Dilemma?

open access: yesMicroorganisms, 2022
Prokaryotic transcription was extensively studied over the last half-century. A great deal of data has been accumulated regarding the control of gene expression by transcription factors regulating their target genes by binding at specific DNA sites ...
Diana Le Berre   +3 more
doaj   +1 more source

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