Results 1 to 10 of about 659,884 (159)

Dynamics of immune system gene expression upon bacterial challenge and wounding in a social insect (Bombus terrestris). [PDF]

PLoS ONE, 2011
The innate immune system which helps individuals to combat pathogens comprises a set of genes representing four immune system pathways (Toll, Imd, JNK and JAK/STAT). There is a lack of immune genes in social insects (e.g.
Silvio Erler, Mario Popp, H Michael G Lattorff   +2 more
doaj   +3 more sources

Saccharomyces boulardii CNCM I-745 Stimulates Intracellular Antimicrobial Activity Against Salmonella Typhimurium in Murine Macrophages [PDF]

Microorganisms
Salmonella enterica serovar Typhimurium (ST) is an intracellular pathogen that survives within macrophages and disseminates to systemic organs, thereby evading host immune defenses.
Rodolphe Pontier-Bres, Dorota Czerucka
doaj   +2 more sources

Implications of gene expression heterogeneity in the interplay between acquired resistance and bacterial metabolism

Scientific Reports
Gene expression heterogeneity has an impact on human bacterial pathogens responses, including antimicrobial resistance genes expression. Promoter region variability in resistance genes may include different regulatory boxes involved in metabolic ...
María Romero-Muñoz, Marina R. Pulido, Esther Recacha, Sara Díaz-Díaz, Marina Murillo-Torres, Fernando Docobo-Pérez, José Manuel Rodríguez-Martínez   +6 more
doaj   +2 more sources

Identification of BvgA-Dependent and BvgA-Independent Small RNAs (sRNAs) in Bordetella pertussis Using the Prokaryotic sRNA Prediction Toolkit ANNOgesic

Microbiology Spectrum, 2021
Noncoding small RNAs (sRNAs) are crucial for the posttranscriptional regulation of gene expression in all organisms and are known to be involved in the regulation of bacterial virulence.
Kyung Moon, Minji Sim, Chin-Hsien Tai, Kyungyoon Yoo, Charlotte Merzbacher, Sung-Huan Yu, David D. Kim, Jaehyun Lee, Konrad U. Förstner, Qing Chen, Scott Stibitz, Leslie G. Knipling, Deborah M. Hinton   +12 more
doaj   +1 more source

Conformational change of the Bordetella response regulator BvgA accompanies its activation of the B. pertussis virulence gene fhaB

Computational and Structural Biotechnology Journal, 2022
The BvgAS two-component system regulates virulence gene expression in Bordetella pertussis. Although precise three-dimensional structural information is not available for the response regulator BvgA, its sequence conservation with E.
David Kim, John Tracey, Manuel Becerra Flores, Kanita Chaudhry, Rafae Nasim, Abraham Correa-Medina, Leslie Knipling, Qing Chen, Scott Stibitz, Lisa M.M. Jenkins, Kyung Moon, Tim Cardozo, Deborah M. Hinton   +12 more
doaj   +1 more source

Transcription profiling reveals potential mechanisms of dysbiosis in the oral microbiome of rhesus macaques with chronic untreated SIV infection. [PDF]

, 2013
A majority of individuals infected with human immunodeficiency virus (HIV) have inadequate access to antiretroviral therapy and ultimately develop debilitating oral infections that often correlate with disease progression.
A Uehara, Aftab A. Ansari, Angeline T. Dang, AR Thurman, AT Dang, BA Dale, BL Shacklett, BP Gomes, Bruce J. Paster, C Beaurepaire, C Gervasoni, C Heise, Chin-Shang Li, Christina Murphy, D Preza, DA Reznik, DR Dixon, E Elinav, E Zaura, F Meurens, FE Dewhirst, G Diamond, G Diamond, G Xie, H Wang, H Yang, HT Rupniak, I Viard-Leveugle, J Benes, J Mitchell, JA Aas, JA Aas, JC Leao, JE Hull, JE Meyer, JM Garcia-Lechuz, JT Arotiba, L Feller, M Bando, M Bruewer, M Guadalupe, M Mittal, M Raffatellu, MD George, MD George, MD George, MH Shaw, Michael D. George, MP George, MT Pollanen, Niku Borujerdpur, P Regenhard, R Saini, RM Zakir, Ross Tarara, RS Veazey, S Chotai, S Gennaro, S Sugawara, Satya Dandekar, Sumathi Sankaran-Walters, Susan Ocon, T Chen, TG Shrihari, W Hartzell, Z Smit-McBride   +65 more
core   +13 more sources

Status quo of tet regulation in bacteria

Microbial Biotechnology, 2022
Summary The tetracycline repressor (TetR) belongs to the most popular, versatile and efficient transcriptional regulators used in bacterial genetics. In the tetracycline (Tc) resistance determinant tet(B) of transposon Tn10, tetR regulates the expression
Ralph Bertram, Bernd Neumann, Christopher F. Schuster   +2 more
doaj   +1 more source

Algorithm for the Reconstruction of Mathematical Frame Models of Bacterial Transcription Regulation

Mathematics, 2022
Transcription regulation plays an important role in bacterial activity. The operon concept coined by François Jacob and Jacques Monod has had a considerable effect on investigations into gene expression regulation, including modeling.
Tatiana N. Lakhova, Fedor V. Kazantsev, Aleksey M. Mukhin, Nikolay A. Kolchanov, Yury G. Matushkin, Sergey A. Lashin   +5 more
doaj   +1 more source

An Adaptable and Modular Set of Laboratory Exercises Connecting Genotype to Phenotype in Sporulating Bacillus subtilis

Journal of Microbiology & Biology Education, 2021
Practical lab exercises that help students draw connections between genotype and phenotype, and make and test predictions about the identity of mutants, are invaluable in college-level cell biology, genetics, and microbiology courses. While many bacteria
Anna L. McLoon, Amy H. Camp, Lilah Rahn-Lee   +2 more
doaj   +1 more source

The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7 [PDF]

, 2014
Classical studies have focused on the role that individual regulators play in controlling virulence gene expression. An emerging theme, however, is that bacterial metabolism also plays a key role in this process.
Abernathy, Anders, Baumler, Bergman, Boehm, Booth, Campellone, Chevance, Clark, Coburn, Creek, Echave, Elliott, Emmerson, Frankel, Fukuda, Fukuda, Hansen, Hartland, Hayashi, Hu, Hu, Hueck, Iyoda, Kendall, Kuhn, Mahajan, Massé, Minato, Nataro, Naylor, Noris, Paul, Porter, Rietsch, Rietsch, Ritchie, Ritchie, Roe, Roe, Scheltema, Shevchenko, Smith, Soutourina, Sullivan, Sánchez-Sanmarti, Thao, Tobe, Tree, Turner, Vytvytska, Wang, Wang, Weinert, Wolfe, Wolfe, Wolfe, Zhang, Zhao, Zumbrun   +59 more
core   +2 more sources