Automated design of bacterial genome sequences [PDF]
, 2013 Background: Organisms have evolved ways of regulating transcription to better adapt to varying environments. Could the current functional genomics data and models support the possibility of engineering a genome with completely rearranged gene ...
Carrera, Javier, Jaramillo, Alfonso
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Mechanism of Gene Regulation by a
mBio, 2016 The virulence of many bacterial pathogens, including the important human pathogen Staphylococcus aureus, depends on the secretion of frequently large amounts of toxins. Toxin production involves the need for the bacteria to make physiological adjustments
Hwang-Soo Joo +8 more
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Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. II. Effect of Bovine Viral Diarrhea Virus on the Endometrial Response to Lipopolysaccharide [PDF]
, 2015 Infection with noncytopathic bovine viral diarrhea virus (ncpBVDV) is associated with uterine disease and infertility. This study investigated the influence of ncpBVDV on immune functions of the bovine endometrium by testing the response to bacterial ...
Abudureyimu, A +6 more
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Bacterial riboswitches and RNA thermometers: Nature and contributions to pathogenesis
Non-coding RNA Research, 2018 Bacterial pathogens are always challenged by fluctuations of chemical and physical parameters that pose serious threats to cellular integrity and metabolic status.
Jameel M. Abduljalil
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Transcriptional control of the H-NS antagonists LeuO and RcsB-BglJ in Escherichia coli [PDF]
, 2012 The bacterial nucleoid-associated protein (NAP) H-NS is involved in the organization and compaction of the bacterial chromatin and acts as a global respressor, mainly of genes that have been acquired by horizontal gene transfer and that are related to ...
Stratmann, Thomas
core
Transcriptional regulation of bacterial virulence gene expression by molecular oxygen and nitric oxide [PDF]
Virulence, 2014 Molecular oxygen (O2) and nitric oxide (NO) are diatomic gases that play major roles in infection. The host innate immune system generates reactive oxygen species and NO as bacteriocidal agents and both require O2 for their production. Furthermore, the ability to adapt to changes in O2 availability is crucial for many bacterial pathogens, as many ...
Matthew D. Rolfe +2 more
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From ingestion to colonization: the influence of the host environment on regulation of the LEE encoded type III secretion system in enterohaemorrhagic Escherichia coli [PDF]
, 2015 Enterohaemorrhagic Escherichia coli (EHEC) binds to host tissue and intimately attaches to intestinal cells using a dedicated type III secretion system (T3SS). This complex multi-protein organelle is encoded within a large pathogenicity island called the
Connolly, J.P., Finlay, B.B., Roe, A.J.
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Diversity and Versatility in Small RNA-Mediated Regulation in Bacterial Pathogens
Frontiers in Microbiology, 2021 Bacterial gene expression is under the control of a large set of molecules acting at multiple levels. In addition to the transcription factors (TFs) already known to be involved in global regulation of gene expression, small regulatory RNAs (sRNAs) are ...
Brice Felden, Yoann Augagneur
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Expression regulation of bacterial lipase genes: a review
Frontiers in MicrobiologyMicrobial lipases constitute the primary source of commercialized and industrial lipases, and they are extensively utilized across numerous industrial sectors. Compared to fungal lipases, bacterial lipases catalyze a broader spectrum of reactions with higher activity, enhanced stability, and improved stress resistance.
Dai-ming Zha, Yun-jun Yan
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The bacterial signal molecule, ppGpp, regulates Salmonella virulence gene expression [PDF]
Molecular Microbiology, 2004 SummaryNumerous, overlapping global regulatory systems mediate the environmental signalling controlling the virulence of Salmonella typhimurium. With both extra‐ and intracellular lifestyles, unravelling the mechanisms involved in regulating Salmonella pathogenesis has been complex.
Karsten Tedin, Javier Pizarro-Cerdá
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