Gac two-component system in Pseudomonas syringae pv. tabaci is required for virulence but not for hypersensitive reaction [PDF]
, 2008 Pseudomonas syringae pv. tabaci 6605 causes wildfire disease on host tobacco plants. To investigate the regulatory mechanism of the expression of virulence, Gac two-Component system-defective mutants, Delta gacA and Delta gacS, and a double mutant, Delta
A Bultreys +38 more
core +1 more source
Orthologous transcription factors in bacteria have different functions and regulate different genes. [PDF]
PLoS Computational Biology, 2007 Transcription factors (TFs) form large paralogous gene families and have complex evolutionary histories. Here, we ask whether putative orthologs of TFs, from bidirectional best BLAST hits (BBHs), are evolutionary orthologs with conserved functions.
Morgan N Price +2 more
doaj +1 more source
Regulation of asymmetries in the kinetics and protein numbers of bacterial gene expression
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2019 Genetic circuits change the status quo of cellular processes when their protein numbers cross thresholds. We investigate the regulation of RNA and protein threshold crossing propensities in Escherichia coli. From in vivo single RNA time-lapse microscopy data from multiple promoters, mutants, induction schemes and media, we study the asymmetry and ...
Sofia Startceva +3 more
openaire +5 more sources
Phytohormone-mediated interkingdom signaling shapes the outcome of rice-Xanthomonas oryzae pv. oryzae interactions [PDF]
, 2015 Background: Small-molecule hormones are well known to play key roles in the plant immune signaling network that is activated upon pathogen perception. In contrast, little is known about whether phytohormones also directly influence microbial virulence ...
De Vleesschauwer, David +7 more
core +2 more sources
Nucleoid-Associated Protein HU: A Lilliputian in Gene Regulation of Bacterial Virulence
Frontiers in Cellular and Infection Microbiology, 2019 Nucleoid-associated proteins belong to a group of small but abundant proteins in bacterial cells. These transcription regulators are responsible for many important cellular processes and also are involved in pathogenesis of bacteria.
Pavla Stojkova, P. Spidlova, J. Stulík
semanticscholar +1 more source
In vivo analysis of staphylococcus aureus-infected mice reveals differential temporal and spatial expression patterns of fhuD2 [PDF]
, 2017 Staphylococcus aureus is an opportunistic human pathogen and a major cause of invasive infections such as bacteremia, endocarditis, pneumonia and wound infections.
Bacconi, Marta +7 more
core +1 more source
Do small RNAs unlock the below ground microbiome-plant interaction mystery?
Frontiers in Molecular Biosciences, 2022 Over the past few decades, regulatory RNAs, such as small RNAs (sRNAs), have received increasing attention in the context of host-microbe interactions due to their diverse roles in controlling various biological processes in eukaryotes.
Roshan Regmi +8 more
doaj +1 more source
A transcriptional regulatory mechanism finely tunes the firing of type VI secretion system in response to bacterial enemies [PDF]
, 2017 The ability to detect and measure danger from an environmental signal is paramount for bacteria to respond accordingly, deploying strategies that halt or counteract potential cellular injury and maximize survival chances. Type VI secretion systems (T6SSs)
Feldman, Mario F +2 more
core +2 more sources
miRNA/phasiRNA mediated regulation of plant defense response against P. syringae [PDF]
, 2018 Gene silencing is a mechanism of regulation of gene expression where the small RNAs (sRNAs) are key components for giving specificity to the system. In plants, two main types of noncoding small RNA molecules have been found: microRNAs (miRNAs) and small ...
Del Espino Pérez, Ángel +7 more
core
ClgR regulation of chaperone and protease systems is essential for Mycobacterium tuberculosis parasitism of the macrophage [PDF]
, 2010 Chaperone and protease systems play essential roles in cellular homeostasis and have vital functions in controlling the abundance of specific cellular proteins involved in processes such as transcription, replication, metabolism and virulence.
Butler, R.E. +7 more
core +3 more sources