Results 81 to 90 of about 651,815 (307)

TetR Regulated in vivo Repression Technology to Identify Conditional Gene Silencing in Genetically Engineerable Bacteria Using Vibrio cholerae Murine Infections as Model System

Bio-Protocol, 2020
Investigation of bacterial gene regulation upon environmental changes is still a challenging task. For example, Vibrio cholerae, a pathogen of the human gastrointestinal tract, faces diverse transient conditions in different compartments upon oral ...
Franz Zingl, Fabian Mitterer, Himadri Thapa, Stefan Schild   +3 more
doaj   +1 more source

Characterization of water and wildlife strains as a subgroup of Campylobacter jejuni using DNA microarrays.

, 2013
Campylobacter jejuni is the leading cause of human bacterial gastroenteritis worldwide, but source attribution of the organism is difficult. Previously, DNA microarrays were used to investigate isolate source, which suggested a non-livestock source of ...
Altschul, Brandl, Champion, Dingle, Dingle, Dorrell, Ethelberg, Francisco, French, Gundogdu, Harris, Hepworth, Hepworth, Hinchliffe, Howard, Huelsenbeck, Jensen, Jorgensen, Joshua, Kalendar, Karenlampi, Katoh, Katoh, Kemp, Kim, Kim, King, Kwan, Kwan, Manning, McCarthy, Mellmann, Miller, Moen, Murphy, Ogden, On, Park, Pearson, Petersen, Ronquist, Rosef, Rosef, Sails, Sanad, Schonberg-Norio, Skirrow, Skirrow, Stabler, Staden, Staden, Taboada, Taboada, Tam, Tam, Wilson   +55 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Transcriptomic Biomarkers to Discriminate Bacterial from Nonbacterial Infection in Adults Hospitalized with Respiratory Illness

Scientific Reports, 2017
Lower respiratory tract infection (LRTI) commonly causes hospitalization in adults. Because bacterial diagnostic tests are not accurate, antibiotics are frequently prescribed. Peripheral blood gene expression to identify subjects with bacterial infection
Soumyaroop Bhattacharya, Alex F. Rosenberg, Derick R. Peterson, Katherine Grzesik, Andrea M. Baran, John M. Ashton, Steven R. Gill, Anthony M. Corbett, Jeanne Holden-Wiltse, David J. Topham, Edward E. Walsh, Thomas J. Mariani, Ann R. Falsey   +12 more
doaj   +1 more source

The Stringent Response Promotes Antibiotic Resistance Dissemination by Regulating Integron Integrase Expression in Biofilms

mBio, 2016
Class 1 integrons are genetic systems that enable bacteria to capture and express gene cassettes. These integrons, when isolated in clinical contexts, most often carry antibiotic resistance gene cassettes.
Emilie Strugeon, Valentin Tilloy, Marie-Cécile Ploy, Sandra Da Re   +3 more
doaj   +1 more source

Expression regulation of bacterial lipase genes: a review

Frontiers in Microbiology
Microbial lipases constitute the primary source of commercialized and industrial lipases, and they are extensively utilized across numerous industrial sectors. Compared to fungal lipases, bacterial lipases catalyze a broader spectrum of reactions with higher activity, enhanced stability, and improved stress resistance.
Dai-ming Zha, Yun-jun Yan
openaire   +2 more sources

Expression systems for industrial Gram-positive bacteria with low guanine and cytosine content [PDF]

, 1997
Recent years have seen an increase in the development of gene expression systems for industrial Gram-positive bacteria with low guanine and cytosine content that belong to the genera Bacillus, Clostridium, Lactococcus, Lactobacillus, Staphylococcus and ...
Kleerebezem, Michiel,, Kuipers, Oscar P.,, Vos, Willem M. de,   +2 more
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Modulating bacterial nanocellulose crystallinity through post-transcriptional repression in Komagataeibacter xylinus

Carbohydrate Polymer Technologies and Applications
Bacterial nanocellulose (BC) is a versatile biomaterial, with its microstructural features fundamentally influencing its properties and functionality across various applications.
Rahul Mangayil, Essi Sarlin, Tom Ellis, Ville Santala   +3 more
doaj   +1 more source