Results 111 to 120 of about 743,593 (306)
Inferring gene expression dynamics via functional regression analysis
Background Temporal gene expression profiles characterize the time-dynamics of expression of specific genes and are increasingly collected in current gene expression experiments.
Leng Xiaoyan +2 more
doaj +1 more source
MicroR159 regulation of most conserved targets in Arabidopsis has negligible phenotypic effects [PDF]
BACKGROUND A current challenge of microRNA (miRNA) research is the identification of biologically relevant miRNA:target gene relationships. In plants, high miRNA:target gene complementarity has enabled accurate target predictions, and slicing of target ...
Allen, Robert S +5 more
core +1 more source
Expression of cytosolic acetyl-CoA synthetase gene is developmentally regulated
Acetyl-CoA synthetase (AceCS) provides acetyl-CoA for different physiological processes, such as fatty acid and cholesterol synthesis, as well as the citric acid cycle. We show here that the cytosolic isoform of this enzyme, AceCS1, is expressed during mouse development. In the embryonic stage E9.5 AceCS1 transcripts localize in the cephalic region. At
Loikkanen, Ildikó +3 more
openaire +2 more sources
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Prey can respond to predation risk through developmental plasticity, generating anti-predator phenotypes. These inducible defenses arise from changes to the stress axis, and neuroendocrine-triggered gene regulation is a likely mechanism influencing such ...
Tucker W. Cambridge +7 more
doaj +1 more source
Diacylglycerol acyltransferases (DGAT) catalyze the final and rate-limiting step of triacylglycerol (TAG) biosynthesis in eukaryotic organisms. DGAT genes have been identified in numerous organisms. Multiple isoforms of DGAT are present in eukaryotes. We
Heping Cao +5 more
doaj +1 more source
Developmental biology of wood formation [PDF]
The wood-forming vascular cambium is responsible for the production of a large part of the biomass on this planet. Yet, there is only limited knowledge on how cell proliferation and differentiation in the cambial meristem are regulated.
Schrader, Jarmo
core
Development of functional ectopic compound eyes in scarabaeid beetles by knockdown of orthodenticle [PDF]
Complex traits like limbs, brains, or eyes form through coordinated integration of diverse cell fates across developmental space and time, yet understanding how complexity and integration emerge from uniform, undifferentiated precursor tissues remains ...
Busey, Hannah A. +3 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Transcript profiling for early stages during embryo development in Scots pine [PDF]
Background: Characterization of the expression and function of genes regulating embryo development in conifers is interesting from an evolutionary point of view.
Abrahamsson, Malin +5 more
core +2 more sources

