Results 61 to 70 of about 437,526 (312)

Genome-Wide Methylation and Gene Expression Changes in Newborn Rats following Maternal Protein Restriction and Reversal by Folic Acid. [PDF]

, 2013
A large body of evidence from human and animal studies demonstrates that the maternal diet during pregnancy can programme physiological and metabolic functions in the developing fetus, effectively determining susceptibility to later disease.
Irina G. Bogdarina (504027), Adrian J L Clark, Stupka, Elia, Langley-Evans Simon, Bogdarina, Irina, Stupka Elia, Altobelli, G, Gioia Altobelli (504026), Elia Stupka, Bogdarina, IG, Altobelli Gioia, Langley-Evans, Simon C., Simon Langley-Evans (367053), Langley-Evans, S, Gioia Altobelli, Bogdarina Irina G., Elia Stupka (23015), Clark, AJ, Clark Adrian J. L., Clark, Adrian J.C., Altobelli, Gioia, Simon Langley-Evans, Adrian J. L. Clark (367055), Irina G Bogdarina, Stupka, E   +24 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Zebrafish rest regulates developmental gene expression but not neurogenesis [PDF]

Development, 2012
The transcriptional repressor Rest (Nrsf) recruits chromatin-modifying complexes to RE1 ‘silencer elements’, which are associated with hundreds of neural genes. However, the requirement for Rest-mediated transcriptional regulation of embryonic development and cell fate is poorly understood. Conflicting views of the role of Rest in controlling cell fate
Fatma O, Kok, Andrew, Taibi, Sarah J, Wanner, Xiayang, Xie, Cara E, Moravec, Crystal E, Love, Victoria E, Prince, Jeff S, Mumm, Howard I, Sirotkin   +8 more
openaire   +2 more sources

Differential Gene Expression and Protein Abundance Evince Ontogenetic Bias toward Castes in a Primitively Eusocial Wasp

, 2010
Polistes paper wasps are models for understanding conditions that may have characterized the origin of worker and queen castes and, therefore, the origin of paper wasp sociality.
Hunt, James H, Toth, Amy L, Thomas C Newman, Amdam, Gro V, Wolschin, Florian, Henshaw Michael T., Michael T Henshaw, Wolschin Florian, Amy L Toth, Toth Amy L., James H Hunt, Amdam Gro V., Gro V Amdam, Hunt James H., Newman Thomas C., Henshaw, Michael T, Newman, Thomas C, Florian Wolschin   +17 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Distinguishing epigenetic marks of developmental and imprinting regulation

Epigenetics & Chromatin, 2010
Background The field of epigenetics is developing rapidly, however we are only beginning to comprehend the complexity of its influence on gene regulation.
McEwen Kirsten R, Ferguson-Smith Anne C
doaj   +1 more source

GSTCD and INTS12 Regulation and Expression in the Human Lung [PDF]

, 2013
Genome-Wide Association Study (GWAS) meta-analyses have identified a strong association signal for lung function, which maps to a region on 4q24 containing two oppositely transcribed genes: glutathione S-transferase, C-terminal domain containing (GSTCD ...
Swan, Caroline, Erik Melén (276082), Ma'en Obeidat, Hao Ke, S. Miller (3494552), Nelson, CP, I. Sayers (3494558), Henry, Amanda P., Probert, Kelly, C. Swan (7390268), Sayers, Ian, Miller Suzanne, K. Probert (7667498), Hodge, E, Maxime Lamontagne (116448), Ma’en Obeidat (460144), Ushey Kevin, Hao, Ke, Dirkje S Postma, Kevin Ushey (181019), Tobin, MD, Wain, LV, Amanda P. Henry (460148), Dirkje S. Postma (101740), Y. Bossé (7628753), Lamontagne, M, Miller, Suzanne, Obeidat Ma’en, Wain, Louise V., Melén Erik, María Soler Artigas (7603997), Caroline Swan (37264), Ceri E. Stewart (460151), Obeidat, Ma'en, Stewart, CE, E. Melén (3494549), Soler Artigas, María, Bossé, Y, Caroline Swan, Kelly Probert (460146), Nelson, Carl P., Nelson Carl P., Stewart Ceri E., Postma, Dirkje S., Lamontagne Maxime, Probert, K, Ceri E Stewart, Hao, K, Carl P Nelson, Hall Ian P., Erik Melén, Ke Hao, Postma Dirkje S., Artigas, Maria Soler, K. Hao (7628756), Billington Charlotte K., Kevin Ushey, Charlotte K. Billington (460147), D. S. Postma (3809164), M. Obeidat (7628729), María Soler Artigas (110124), Louise V. Wain (7588511), Martin D Tobin, Carl P. Nelson (460150), Ushey, Kevin, Ian Sayers, C. P. Nelson (7591670), Tobin Martin D., Ian P. Hall (110307), Hodge, Emily, Ian P Hall, Maxime Lamontagne, Louise V Wain, C. K. Billington (7667501), Emily Hodge (460149), Ke Hao (50181), Wain Louise V., Bossé Yohan, Sayers, I, Ushey, K, Hall, IP, Louise V. Wain (110260), Amanda P Henry, Emily Hodge, Artigas, MS, C. E. Stewart (7627559), Melen, Erik, E. Hodge (7643807), Billington, Charlotte K., Suzanne Miller, Obeidat, Ma�en, Henry Amanda P., Soler Artigas, Mar�a, Hodge Emily, Probert Kelly, Obeidat, M, Lamontagne, Maxime, Billington, CK, K. Ushey (7667507), Boss�, Yohan, Melén, E, A. P. Henry (7667504), Sayers Ian, Swan, C, Kelly Probert, Stewart, Ceri E., Obeidat, Ma’en, Ian Sayers (37266), Martin D. Tobin (7581161), Artigas María Soler, Henry, AP, Postma, DS, Yohan Bossé (69571), Hall, Ian P., Tobin, Martin D., Suzanne Miller (460145), Yohan Bossé, M. Lamontagne (7667510), Swan Caroline, Martin D. Tobin (110311), Mel�n, Erik, Miller, S, Charlotte K Billington, María Soler Artigas, Bosse, Yohan, I. P. Hall (7628774)   +125 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Spatiotemporal expression patterns of cytosolic AtHSP90-2 in Arabidopsis seedlings

Plant Signaling & Behavior, 2023
Heat shock protein AtHSP90–2 is one of the three constitutive cytosolic HSP90s of Arabidopsis thaliana, which are highly homologous and show mild expression activation in response to stressful impacts.
Liudmyla Kozeko, Elizabeth Kordyum
doaj   +1 more source

Gene Expression Modifications by Temperature-Toxicants Interactions in Caenorhabditis elegans

, 2011
Although organophosphorus pesticides (OP) share a common mode of action, there is increased awareness that they elicit a diverse range of gene expression responses.
Vinuela Rodriguez, A., Kammenga Jan E., Joost A. G. Riksen, Riksen Joost A. G., Ana Viñuela, L Basten Snoek, Viñuela Ana, Jan E. Kammenga, Joost A G Riksen, Kammenga, J.E., Snoek, L.B., L. Basten Snoek, Jan E Kammenga, Snoek L. Basten, Riksen, J.A.G.   +14 more
core   +1 more source