DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Heat Shock Transcription Factors as Central Integrators of Plant Stress Responses: From Thermotolerance to Multi-Stress Resilience. [PDF]
Li Y, Gong K, Wang X, Sun Z, Ding F.
europepmc +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Histone Deacetylase BpHST1 Regulates Plant Architecture and Photosynthesis in Birch. [PDF]
Hou L, Li B, Ge M, Zheng Z.
europepmc +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Physiological and gene expression analysis of Hevea brasiliensis under drought stress. [PDF]
Mohammadi Nodehi M +6 more
europepmc +1 more source
Regulator of G-Protein Signalling Protein AaRgs2 Negatively Regulates Appressorium-Like Formation of Alternaria alternata Induced by Pear Cutin Monomer via the AaRgs2-AaGα1-AaAC Module. [PDF]
Zhang M, Nan Y, Li Y, Bi Y, Prusky DB.
europepmc +1 more source
Rice miRNA-mediated trans-kingdom gene regulation in pathogenic and symbiotic fungal interactions. [PDF]
Jannesar M +5 more
europepmc +1 more source
Genome-wide identification and expression analysis of the Small Ubiquitin-like Modifier (SUMO) gene family in Triticum aestivum L. [PDF]
Kesawat MS +11 more
europepmc +1 more source
SEdb 3.0: a comprehensive super-enhancer database across multiple species. [PDF]
Song S +12 more
europepmc +1 more source

