Results 81 to 90 of about 267,816 (318)

Splayed : a chromatin remodeler regulating tissue specific gene silencing and developmental timing [PDF]

, 2014
A number of mechanisms that contribute to epigenetic regulation of gene expression have been described in plants. The concert actions of these mechanisms contribute to proper patterning of gene expression within organs and tissues, therefore insuring ...
Fal, Kateryna
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Using systems biology approaches to elucidate gene regulatory networks controlling the plant defence response [PDF]

Transcriptional regulation controlling pathogen-responsive gene expression in Arabidopsis is believed to underlie the plant defence response, which confers partial immunity of Arabidopsis to infection by Botrytis cinerea.
Kiddle, Steven J.
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Genome-Wide Identification, Functional Analysis and Expression Profiling of the Aux/IAA Gene Family in Tomato [PDF]

, 2012
Auxin is a central hormone that exerts pleiotropic effects on plant growth including the development of roots, shoots, flowers and fruit. The perception and signaling of the plant hormone auxin rely on the cooperative action of several components,among
Regad, Farid, Bassa, Carole, Delalande, Corinne, Mila, Isabelle, Zouine, Mohamed, Bouzayen, Mondher   +5 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

The genetically programmed rhythmic alteration of diurnal gene expression in the aged Arabidopsis leaves

Frontiers in Plant Science
The circadian clock regulates the daily pattern of temporal gene expression. In Arabidopsis, aging is associated with a shortening of the endogenous period of circadian rhythms under circadian conditions.
Sukjoon Jung, Sukjoon Jung, Hyunmin Kim, Juhyeon Lee, Myeong Hoon Kang, Jungyeon Kim, Jong Kyoung Kim, Jong Kyoung Kim, Pyung Ok Lim, Hong Gil Nam, Hong Gil Nam, Hong Gil Nam   +11 more
doaj   +1 more source

Integrative analyses of genetic variation in enzyme activities of primary carbohydrate metabolism reveal distinct modes of regulation in Arabidopsis thaliana

, 2008
Background Plant primary carbohydrate metabolism is complex and flexible, and is regulated at many levels. Changes of transcript levels do not always lead to changes in enzyme activities, and these do not always affect metabolite levels and fluxes.
Fu, Jingyuan, Vreugdenhil, Dick, Fu, Jingyuan; id_orcid, Keurentjes, Joost Jb, Keurentjes, J. J. B., Steinhauser, Marie-Caroline, Koornneef, Maarten, Koornneef, M., Steinhauser, M. C., Steinhauser, M., Steinhauser, C., Keurentjes, Joost J. B., Keurentjes, J., Gibon, Y., Keurentjes, J.J.B., Sulpice, R., Gibon, Yves, Stitt, M., Steinhauser, M.C., Sulpice, Ronan, Vreugdenhil, D., Fu, J. Y., Fu, J., Stitt, Mark   +23 more
core   +1 more source