Results 81 to 90 of about 250,469 (267)

Editorial: Bioinformatics of Genome Regulation, Volume II

Frontiers in Genetics, 2021
Yuriy L. Orlov, Yuriy L. Orlov, Anastasia A. Anashkina, Anastasia A. Anashkina, Tatiana V. Tatarinova, Ancha V. Baranova, Ancha V. Baranova   +6 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Take control of expression: effector-mediated modulation of the host transcriptional machinery

Frontiers in Plant Science
Interactions between plants and microbes that colonize them typically result in significant alterations of the host’s gene expression. Such transcriptional changes include modulation of immune responses, as well as orchestrating metabolic and ...
Weiliang Zuo, Muye Xiao, Gunther Doehlemann   +2 more
doaj   +1 more source

Global Methylomic and Transcriptomic Analyses Reveal the Broad Participation of DNA Methylation in Daily Gene Expression Regulation of Populus trichocarpa

Frontiers in Plant Science, 2019
Changes in DNA methylation patterns in different tissues, at various developmental stages, and under environmental stimuli have been investigated in plants.
Lixiong Liang, Lixiong Liang, Yingying Chang, Yingying Chang, Junqian Lu, Junqian Lu, Xiaojuan Wu, Xiaojuan Wu, Qi Liu, Qi Liu, Weixi Zhang, Weixi Zhang, Xiaohua Su, Xiaohua Su, Bingyu Zhang, Bingyu Zhang   +15 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Identification of Co-Expression Modules of Cotton Plant Height-Related Genes Based on Weighted Gene Co-Expression Network Analysis

Agronomy
Plant height (PH) is a vital agronomic trait that significantly affects cotton yield and facilitates mechanized harvesting. Gaining insights into the genetic regulatory mechanisms governing plant height is fundamental to advancing cotton breeding.
Qian Huang, Li Liu, Hang Li, Xuwen Wang, Aijun Si, Liangrong He, Yu Yu   +6 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Positive Regulation of the Hrp Type III Secretion System in Pseudomonas syringae pv. phaseolicola

Molecular Plant-Microbe Interactions, 2010
Disease in compatible hosts and induction of the hypersensitive response in resistant plants by most plant-pathogenic bacteria require a functional type III secretion system (T3SS).
Inmaculada Ortiz-Martín, Richard Thwaites, Alberto P. Macho, John W. Mansfield, Carmen R. Beuzón   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

EjGASA6 promotes flowering and root elongation by enhancing gibberellin biosynthesis

Journal of Integrative Agriculture
The Gibberellic Acid-stimulated Arabidopsis (GASA) gene family is involved in the regulation of gene expression and plant growth, development, and stress responses.
Qian Chen, Shunyuan Yong, Fan Xu, Hao Fu, Jiangbo Dang, Qiao He, Danlong Jing, Di Wu, Guolu Liang, Qigao Guo   +9 more
doaj   +1 more source