Nascent RNA sequencing reveals mechanisms of gene regulation in the human malaria parasite Plasmodium falciparum. [PDF]
, 2017 Gene expression in Plasmodium falciparum is tightly regulated to ensure successful propagation of the parasite throughout its complex life cycle. The earliest transcriptomics studies in P.
Batugedara, Gayani +5 more
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Hypoxia and Inflammation in Cancer, Focus on HIF and NF-κB
Biomedicines, 2017 Cancer is often characterised by the presence of hypoxia and inflammation. Paramount to the mechanisms controlling cellular responses under such stress stimuli, are the transcription factor families of Hypoxia Inducible Factor (HIF) and Nuclear Factor of
Laura D’Ignazio +2 more
doaj +1 more source
Regulation of Tobamovirus Gene Expression
, 1990 This chapter discusses tobacco mosaic virus (TMV) strains U1, OM, L, CGMMV, 0, and Cc. The production of each TMV protein is regulated differently, both in amounts and times of production. The chapter discusses some of the strategies that tobamoviruses uses to control gene expression: (1) different subgenomic RNA promoter/leader sequences control ...
William O. Dawson, Kirsi Lehto
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Patterns of subnet usage reveal distinct scales of regulation in the transcriptional regulatory network of Escherichia coli [PDF]
, 2010 The set of regulatory interactions between genes, mediated by transcription factors, forms a species' transcriptional regulatory network (TRN). By comparing this network with measured gene expression data one can identify functional properties of the TRN
A Travers +31 more
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Proteomic analysis of the response to cell cycle arrests in human myeloid leukemia cells
eLife, 2015 Previously, we analyzed protein abundance changes across a ‘minimally perturbed’ cell cycle by using centrifugal elutriation to differentially enrich distinct cell cycle phases in human NB4 cells (Ly et al., 2014).
Tony Ly, Aki Endo, Angus I Lamond
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Regulation of Murine Class I Genes by Interferons is Controlled by Regions Located Both 5' and 3' to the Transcription Initiation Site [PDF]
, 1987 Interferons regulate the expression of a large number of mammalian genes, including the major histocompatibility antigen genes. To investigate the mechanisms involved in interferon action, we have analyzed the ability of murine H-2Ld and H-2Dd DNA ...
Hood, Leroy +2 more
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TcZC3HTTP, a regulatory element that contributes to Trypanosoma cruzi cell proliferation
Microbiology SpectrumPost-transcriptional regulation of gene expression is a critical process for adapting to and surviving Trypanosoma cruzi, a parasite with a complex life cycle.
Bruno Accioly Alves Romagnoli +5 more
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Molecular Basis of the Function of Transcriptional Enhancers
Cells, 2020 Transcriptional enhancers are major genomic elements that control gene activity in eukaryotes. Recent studies provided deeper insight into the temporal and spatial organization of transcription in the nucleus, the role of non-coding RNAs in the process ...
Airat N. Ibragimov +2 more
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Gene Expression Regulation by Upstream Open Reading Frames and Human Disease
PLoS Genetics, 2013 Upstream open reading frames (uORFs) are major gene expression regulatory elements. In many eukaryotic mRNAs, one or more uORFs precede the initiation codon of the main coding region.
C. Barbosa, I. Peixeiro, L. Romão
semanticscholar +1 more source
Decrease in gyrase A protein expression in _E. coli_ cells inhibited by antisense ribozymes [PDF]
, 2008 RNase P complexed with external guide sequence (EGS) represents a novel nucleic-acid-based gene interference approach to modulate gene expression. Nucleic acid-based gene interference technologies represent promising strategies for specific inhibition of
Malathi Raghunathan +1 more
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