Results 21 to 30 of about 5,894,586 (297)

The gap gene network [PDF]

open access: yesCellular and Molecular Life Sciences, 2010
Gap genes are involved in segment determination during the early development of the fruit fly Drosophila melanogaster as well as in other insects. This review attempts to synthesize the current knowledge of the gap gene network through a comprehensive survey of the experimental literature.
openaire   +2 more sources

tmnolan/Brassinosteroid-gene-regulatory-networks-at-cellular-resolution: Brassinosteroid gene regulatory networks at cellular resolution in the Arabidopsis root

open access: yes, 2022
This code accompanies the manuscript "Brassinosteroid gene regulatory networks at cellular resolution in the Arabidopsis root"
Hsu-Che-Wei   +2 more
core   +1 more source

LncRNA EPR controls epithelial proliferation by coordinating Cdkn1a transcription and mRNA decay response to TGF-β

open access: yesNature Communications, 2019
Several lncRNAs are regulated by TGF-β. Here the authors report that an intergenic lncRNA —EPR— is a component of the TGF-β signaling pathway and controls epithelial cell proliferation by altering transcription and mRNA decay of Cdkn1a.
Martina Rossi   +14 more
doaj   +1 more source

Fishing Innate Immune System Properties through the Transcriptomic Single-Cell Data of Teleostei

open access: yesBiology, 2023
The innate immune system is the first line of defense in multicellular organisms. Danio rerio is widely considered a promising model for IIS-related research, with the most amount of scRNAseq data available among Teleostei. We summarized the scRNAseq and
Aleksandr V. Bobrovskikh   +2 more
doaj   +1 more source

Growing Bayesian network models of gene networks from seed genes [PDF]

open access: yesBioinformatics, 2005
Abstract Motivation: For the last few years, Bayesian networks (BNs) have received increasing attention from the computational biology community as models of gene networks, though learning them from gene-expression data is problematic. Most gene-expression databases contain measurements for thousands of genes, but the existing algorithms
José M. Peña 0001   +2 more
openaire   +3 more sources

Quantifying the interplay between genetic and epigenetic regulations in stem cell development

open access: yesNew Journal of Physics, 2019
Waddington epigenetic landscape, as a classic metaphor, has been used to explain cellular development and differentiation. However, it remains challenging to quantify the epigenetic landscape.
Yunbin Zhang   +3 more
doaj   +1 more source

Joint conditional Gaussian graphical models with multiple sources of genomic data

open access: yesFrontiers in Genetics, 2013
It is challenging to identify meaningful gene networks because biologicalinteractions are often condition-specific and confounded with externalfactors. It is necessary to integrate multiple sources of genomicdata to facilitate network inference.
Hyonho eChun   +3 more
doaj   +1 more source

Extending gene ontology with gene association networks [PDF]

open access: yesBioinformatics, 2015
Abstract Motivation: Gene ontology (GO) is a widely used resource to describe the attributes for gene products. However, automatic GO maintenance remains to be difficult because of the complex logical reasoning and the need of biological knowledge that are not explicitly represented in the GO.
Jiajie Peng   +4 more
openaire   +3 more sources

A multi‐level approach reveals key physiological and molecular traits in the response of two rice genotypes subjected to water deficit at the reproductive stage

open access: yesPlant-Environment Interactions, 2023
Rice is more vulnerable to drought than maize, wheat, and sorghum because its water requirements remain high throughout the rice life cycle. The effects of drought vary depending on the timing, intensity, and duration of the events, as well as on the ...
Bénédicte Favreau   +11 more
doaj   +1 more source

Nonparametric Bayesian inference for perturbed and orthologous gene regulatory networks [PDF]

open access: yes, 2012
Motivation: The generation of time series transcriptomic datasets collected under multiple experimental conditions has proven to be a powerful approach for disentangling complex biological processes, allowing for the reverse engineering of gene ...
Penfold, Christopher A.   +3 more
core   +1 more source

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