Results 31 to 40 of about 5,894,586 (297)

Synchrony in Gene Regulatory Networks

open access: yesPhysica D: Nonlinear phenomena, 2021
We consider two mathematical dynamical models of gene regulatory networks (GRNs) and obtain results on robust synchronization on these dynamical models based on the existing theoretical results in the coupled cell network formalism. We also explore the concepts of quotient networks and network lifting in the context of GRNs which are related to the ...
Aguiar, Manuela A. D.   +2 more
openaire   +2 more sources

Plasma cortisol-linked gene networks in hepatic and adipose tissues implicate corticosteroid-binding globulin in modulating tissue glucocorticoid action and cardiovascular risk

open access: yesFrontiers in Endocrinology, 2023
Genome-wide association meta-analysis (GWAMA) by the Cortisol Network (CORNET) consortium identified genetic variants spanning the SERPINA6/SERPINA1 locus on chromosome 14 associated with morning plasma cortisol, cardiovascular disease (CVD), and ...
Sean Bankier   +18 more
doaj   +1 more source

Using large-scale perturbations in gene network reconstruction [PDF]

open access: yes, 2005
Background: Recent analysis of the yeast gene network shows that most genes have few inputs, indicating that enumerative gene reconstruction methods are both useful and computationally feasible.
Andrew Pomiankowski   +8 more
core   +1 more source

Gene Regulation: Gene Control Network in Development [PDF]

open access: yesAnnual Review of Biophysics and Biomolecular Structure, 2007
Controlling the differential expression of many thousands of genes is the most fundamental task of a developing organism. It requires an enormous computational device that has the capacity to process in parallel a vast number of regulatory inputs in the various cells of the embryo and come out with regulatory outputs that are tissue specific.
Ben-Tabou de-Leon, Samadar   +1 more
openaire   +3 more sources

Deciphering tissue-specific protein regulation for insights into cardiometabolic disease

open access: yesMolecular Metabolism
Understanding tissue-specific mechanisms of protein regulation gives crucial insights into cardiometabolic disease and informs drug discovery. Most proteomic studies have primarily concentrated on plasma, overlooking tissue-specific effects.
April E. Hartley   +11 more
doaj   +1 more source

Evolution under fluctuating environments explains observed robustness in metabolic networks [PDF]

open access: yes, 2010
Copyright: © 2010 Soyer, Pfeiffer. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and ...
Pfeiffer, Thomas   +6 more
core   +1 more source

mSphere of Influence: Comprehensive Genetic Analysis

open access: yesmSphere, 2020
Jason M. Peters works in the fields of antibiotic resistance and biofuel production. In this mSphere of Influence article, he reflects on how the paper “A global genetic interaction network maps a wiring diagram of cellular function” by Costanzo et al ...
Jason M. Peters
doaj   +1 more source

Artificial intelligence in diabetology

open access: yesСахарный диабет, 2021
This review presents the applications of artificial intelligence for the study of the mechanisms of diabetes development and generation of new technologies of its prevention, monitoring and treatment.
V. V. Klimontov   +2 more
doaj   +1 more source

Reliable transfer of transcriptional gene regulatory networks between taxonomically related organisms [PDF]

open access: yes, 2009
Baumbach J, Rahmann S, Tauch A. Reliable transfer of transcriptional gene regulatory networks between taxonomically related organisms. BMC Systems Biology.
Sven Rahmann   +5 more
core   +1 more source

Determining the Properties of Gene Regulatory Networks from Expression Data

open access: yes, 2009
Recent advances in gene sequencing technology are now shedding light on the complex interplay between genes that elicit phenotypic behavior characteristic of any given organism.
Shehadeh, Lina   +4 more
core   +2 more sources

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