Results 1 to 10 of about 9,994,010 (387)
Gene Regulation and Speciation. [PDF]
Trends in Genetics, 2017 Understanding the genetic architecture of speciation is a major goal in evolutionary biology. Hybrid dysfunction is thought to arise most commonly through negative interactions between alleles at two or more loci. Divergence between interacting regulatory elements that affect gene expression (i.e., regulatory divergence) may be a common route for these
Katya L. Mack, M. Nachman
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The evolution of gene regulation
eLife, 2017 The gene regulation mechanisms necessary for the development of complex multicellular animals have been found in sponges.
V. Hinman, G. Cary
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Regulation of the Erythropoietin Gene [PDF]
, 1989 In man and other mammals the red cell mass is regulated by the hormone erythropoietin (Epo). This glycoprotein is produced in the fetal liver1 and the adult kidney2 in response to hypoxia. The hormone travels to hematopoietic tissues where it stimulates the proliferation and differentiation of erythroid progenitor cells.
Shigehiko Imagawa +2 more
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Gene Regulation and Transcriptomics [PDF]
Current Issues in Molecular Biology, 2021 Borrelia (Borreliella) burgdorferi, along with closely related species, is the etiologic agent of Lyme disease. The spirochete subsists in an enzootic cycle that encompasses acquisition from a vertebrate host to a tick vector and transmission from a tick vector to a vertebrate host.
Samuels, D. Scott +8 more
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Cell & Bioscience, 2022 Background Bile acid (BA) homeostasis is mainly regulated by bile salt excretory pump (BSEP), a hepatocyte transporter that transfers BAs to the bile.
Javier Martínez-García +6 more
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CTCF and cohesin promote focal detachment of DNA from the nuclear lamina
Genome Biology, 2022 Background Lamina-associated domains (LADs) are large genomic regions that are positioned at the nuclear lamina. It has remained largely unclear what drives the positioning and demarcation of LADs.
Tom van Schaik +5 more
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Transcription factors: Bridge between cell signaling and gene regulation
Proteomics, 2021 Transcription factors (TFs) are key regulators of intrinsic cellular processes, such as differentiation and development, and of the cellular response to external perturbation through signaling pathways.
Paula Weidemüller +3 more
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The role of CPEB family proteins in the nervous system function in the norm and pathology
Cell & Bioscience, 2021 Posttranscriptional gene regulation includes mRNA transport, localization, translation, and regulation of mRNA stability. CPEB (cytoplasmic polyadenylation element binding) family proteins bind to specific sites within the 3′-untranslated region and ...
Eugene Kozlov +4 more
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Regulation of the Globin Genes [PDF]
Pediatric Research, 2002 The a- and b-globin gene clusters are subject to several levels of regulation. They are expressed exclusively in the erythroid cells, only during defined periods of development and in a perfectly tuned way, assuring, at any stage of ontogeny, a correct balance in the availability of a- and b-globin chains for hemoglobin assembling. Such a tight control
Cao A, MOI, PAOLO
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Scientific Reports, 2021 Transcriptional coactivator PGC-1α and its splice variant NT-PGC-1α regulate metabolic adaptation by modulating many gene programs. Selective ablation of PGC-1α attenuates diet-induced obesity through enhancing fatty acid oxidation and thermogenesis by ...
Jihyun Kim +6 more
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