Results 31 to 40 of about 786,474 (343)
Gene regulatory networks for development [PDF]
Proceedings of the National Academy of Sciences, 2005 The genomic program for development operates primarily by the regulated expression of genes encoding transcription factors and components of cell signaling pathways. This program is executed by cis-regulatory DNAs (e.g., enhancers and silencers) that control gene expression.
Levine, Michael, Davidson, Eric H.
openaire +3 more sources
Literature-based priors for gene regulatory networks [PDF]
, 2009 Motivation: The use of prior knowledge to improve gene regulatory network modelling has often been proposed. In this paper we present the first research on the massive incorporation of prior knowledge from literature for Bayesian network learning of gene
't Hoen, PAC +3 more
core +2 more sources
Model Checking Gene Regulatory Networks [PDF]
, 2015 19 pages, 20 references, 4 ...
Mirco Giacobbe +5 more
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Approximate kernel reconstruction for time-varying networks
BioData Mining, 2019 Background Most existing algorithms for modeling and analyzing molecular networks assume a static or time-invariant network topology. Such view, however, does not render the temporal evolution of the underlying biological process as molecular networks ...
Gregory Ditzler +3 more
doaj +1 more source
Gene autoregulation via intronic microRNAs and its functions [PDF]
, 2012 Background: MicroRNAs, post-transcriptional repressors of gene expression, play a pivotal role in gene regulatory networks. They are involved in core cellular processes and their dysregulation is associated to a broad range of human diseases.
Baroudi, Mariama El +4 more
core +2 more sources
Gene regulatory network subcircuit controlling a dynamic spatial pattern of signaling in the sea urchin embryo [PDF]
, 2008 We dissect the transcriptional regulatory relationships coordinating the dynamic expression patterns of two signaling genes, wnt8 and delta, which are central to specification of the sea urchin embryo endomesoderm.
Alifragis +34 more
core +3 more sources
Understanding Tissue-Specific Gene Regulation
Cell Reports, 2017 Summary: Although all human tissues carry out common processes, tissues are distinguished by gene expression patterns, implying that distinct regulatory programs control tissue specificity.
Abhijeet Rajendra Sonawane +9 more
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Artificial Gene Regulatory Networks—A Review [PDF]
Artificial Life, 2019 In nature, gene regulatory networks are a key mediator between the information stored in the DNA of living organisms (their genotype) and the structural and behavioral expression this finds in their bodies, surviving in the world (their phenotype). They integrate environmental signals, steer development, buffer stochasticity, and allow evolution to ...
Cussat-Blanc, Sylvain +2 more
openaire +4 more sources
Calculating Biological Behaviors of Epigenetic States in Phage lambda Life Cycle [PDF]
, 2004 Gene regulatory network of lambda phage is one the best studied model systems in molecular biology. More 50 years of experimental study has provided a tremendous amount of data at all levels: physics, chemistry, DNA, protein, and function.
Ao, P., Hood, L., Yin, L., Zhu, X. -M.
core +1 more source
Variable levels of drift in tunicate cardiopharyngeal gene regulatory elements
EvoDevo, 2019 Background Mutations in gene regulatory networks often lead to genetic divergence without impacting gene expression or developmental patterning. The rules governing this process of developmental systems drift, including the variable impact of selective ...
William Colgan +25 more
doaj +1 more source